PanelApp (staging)
  1. Genes and Genomic Entities
  2. TMPRSS6

TMPRSS6

transmembrane protease, serine 6
OMIM: 609862, ClinGen, DECIPHER

3 panels

Panel Reviews Mode of inheritance Details
3 panels

Green TMPRSS6 in Mendeliome


Version 1.2302

1 review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Victorian Clinical Genetics Services
Phenotypes
  • Iron-refractory iron deficiency anaemia MIM# 206200
  • Iron malabsorption
  • hypochromic microcytic anaemia

Green TMPRSS6 in Red cell disorders


Level 2: Haematological disorders
Version 1.29

1 review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Yorkshire and North East GLH
  • NHS GMS
  • Wessex and West Midlands GLH
  • North West GLH
Phenotypes
  • Iron-refractory iron deficiency anaemia MIM# 206200
  • Iron malabsorption
  • hypochromic microcytic anaemia

Green TMPRSS6 in Metal Metabolism Disorders


Level 2: Metabolic disorders
Version 0.45

Component of the following Super Panels:

  • Metabolic Disorders Superpanel
  • Progressive Neurological Conditions

    		•  1 review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • NHS Genomic Medicine Service
    • Expert Review Green
    • Genomics England PanelApp
    Phenotypes
    • IRIDA
    • 206200 Iron-refractory iron deficiency anemia
    • 206200 IRON-REFRACTORY IRON DEFICIENCY ANEMIA