SMAD6

SMAD family member 6
OMIM: 602931, ClinGen, DECIPHER

8 panels

Panel Reviews Mode of inheritance Details
8 panels

Amber SMAD6 in Aortopathy_Connective Tissue Disorders


Level 2: Cardiovascular disorders
Version 1.86

2 reviews MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Amber
  • Literature
Phenotypes
  • Aortic valve disease 2 MIM# 614823

Green SMAD6 in Congenital Heart Defect


Level 2: Cardiovascular disorders
Version 0.430

0 reviews Unknown
Sources
  • Victorian Clinical Genetics Services
  • Expert Review Green

Green SMAD6 in Craniosynostosis


Level 2: Dysmorphic and congenital abnormality syndromes
Version 1.68

2 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Literature
Phenotypes
  • {Craniosynostosis 7, susceptibility to}, MIM# 617439

Green SMAD6 in Mendeliome


Version 1.2302

1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Victorian Clinical Genetics Services
Phenotypes
  • {Radioulnar synostosis, nonsyndromic} 179300
  • {Craniosynostosis 7, susceptibility to} 617439
  • Aortic valve disease 2 MIM# 614823

Green SMAD6 in Skeletal dysplasia

Level 3: Skeletal dysplasias
Level 2: Skeletal disorders
Version 0.302

2 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Expert Review
Phenotypes
  • {Radioulnar synostosis, nonsyndromic} 179300

Red SMAD6 in Additional findings_Paediatric


Level 2: Screening
Version 0.278

0 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Red
  • BabySeq Category C gene
Phenotypes
  • Cardiovascular malformation, congenital

Green SMAD6 in Fetal anomalies


Version 1.313

1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Expert list
  • Literature
Phenotypes
  • Aortic valve disease 2 - MIM#614823
  • {Craniosynostosis 7, susceptibility to} - MIM#617439
  • {Radioulnar synostosis, nonsyndromic} - #179300

Red SMAD6 in BabyScreen+ newborn screening


Level 2: Screening
Version 1.116

0 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • BabySeq Category C gene
  • Expert Review Red
Phenotypes
  • Cardiovascular malformation, congenital