SKI

SKI proto-oncogene
OMIM: 164780, ClinGen, DECIPHER

14 panels

Panel Reviews Mode of inheritance Details
14 panels

Green SKI in Aortopathy_Connective Tissue Disorders


Level 2: Cardiovascular disorders
Version 1.86

2 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Victorian Clinical Genetics Services
Phenotypes
  • Shprintzen-Goldberg syndrome, MIM#182212

Green SKI in Arthrogryposis


Level 2: Neurology and neurodevelopmental disorders
Version 0.416

0 reviews Unknown
Sources
  • Victorian Clinical Genetics Services
  • Expert Review Green

Green SKI in Bleeding and Platelet Disorders


Level 2: Haematological disorders
Version 1.52

2 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Expert Review Green
  • Victorian Clinical Genetics Services
Phenotypes
  • Shprintzen-Goldberg syndrome, MIM# 182212

Green SKI in Craniosynostosis


Level 2: Dysmorphic and congenital abnormality syndromes
Version 1.68

2 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Literature
Phenotypes
  • Shprintzen-Goldberg syndrome, MIM# 182212

Green SKI in Hydrocephalus_Ventriculomegaly


Level 2: Neurology and neurodevelopmental disorders
Version 0.127

0 reviews Unknown
Sources
  • Victorian Clinical Genetics Services
  • Expert Review Green

Green SKI in Mendeliome


Version 1.2302

2 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Victorian Clinical Genetics Services
Phenotypes
  • Shprintzen-Goldberg syndrome, MIM#182212

Green SKI in Callosome


Level 2: Neurology and neurodevelopmental disorders
Version 0.540

0 reviews Unknown
Sources
  • Victorian Clinical Genetics Services
  • Expert Review Green

Green SKI in Intellectual disability syndromic and non-syndromic


Level 2: Neurology and neurodevelopmental disorders
Version 1.63

2 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Genetic Health Queensland
Phenotypes
  • Shprintzen-Goldberg syndrome, MIM# 182212
  • Neurodevelopmental disorder, MONDO:0700092, SKI-related

Green SKI in Skeletal dysplasia

Level 3: Skeletal dysplasias
Level 2: Skeletal disorders
Version 0.302

2 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Expert Review Green
  • Expert list
  • Radboud University Medical Center, Nijmegen
  • NHS GMS
  • Victorian Clinical Genetics Services
Phenotypes
  • Shprintzen-Goldberg syndrome 182212

Green SKI in Additional findings_Paediatric


Level 2: Screening
Version 0.278

0 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • BabySeq Category A gene
  • Expert Review Green
Phenotypes
  • Shprintzen-Goldberg syndrome

Green SKI in Clefting disorders

Level 3: Dysmorphic disorders
Level 2: Dysmorphic and congenital abnormality syndromes
Version 0.260

0 reviews MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Green
Phenotypes
  • SHPRINTZEN-GOLDBERG CRANIOSYNOSTOSIS SYNDROME
  • SGS

Green SKI in Fetal anomalies


Version 1.313

2 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Genomics England PanelApp
Phenotypes
  • Shprintzen-Goldberg syndrome, MIM#182212

Red SKI in BabyScreen+ newborn screening


Level 2: Screening
Version 1.116

1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Red
  • BabySeq Category A gene
Phenotypes
  • Shprintzen-Goldberg syndrome, MIM#182212

Green SKI in Transplant Co-Morbidity Superpanel


Level 2: Screening
Version 0.18

0 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Victorian Clinical Genetics Services
Phenotypes
  • Shprintzen-Goldberg syndrome, MIM# 182212