PanelApp (staging)
  1. Genes and Genomic Entities
  2. SDHC

SDHC

succinate dehydrogenase complex subunit C
OMIM: 602413, ClinGen, DECIPHER

12 panels

Panel Reviews Mode of inheritance Details
12 panels

Green SDHC in Incidentalome


Version 0.318

1 review Unknown
Sources
  • Expert Review Green
  • Melbourne Genomics Health Alliance
  • Victorian Clinical Genetics Services
  • Expert Review Green

Green SDHC in Cancer Predisposition_Paediatric


Level 2: Cancer
Version 0.131

1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Victorian Clinical Genetics Services
Phenotypes
  • Paragangliomas 3, MIM# 605373

Red SDHC in Mitochondrial disease


Level 2: Metabolic disorders
Version 0.969

Component of the following Super Panels:

  • Metabolic Disorders Superpanel
  • Progressive Neurological Conditions

    		•  0 reviews Unknown
    Sources
    • Expert Review Red
    Phenotypes
    • Mitochondrial disease MONDO:0044970

    Green SDHC in Additional findings_Adult


    Level 2: Screening
    Version 0.169

    		1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • Melbourne Genomics Health Alliance
    Phenotypes
    • Paragangliomas 3, MIM# 605373

    Amber SDHC in Additional findings_Paediatric


    Level 2: Screening
    Version 0.278

    		0 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Amber
    • BabySeq Category B gene
    Phenotypes
    • Hereditary Paraganglioma-Pheochromocytoma Syndromes

    Green SDHC in Incidentalome_PREGEN_DRAFT


    Version 0.43

    		1 review Unknown
    Sources
    • NSW Health Pathology
    • Expert Review Green

    Amber SDHC in BabyScreen+ newborn screening


    Level 2: Screening
    Version 1.116

    		0 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • BabySeq Category B gene
    • Expert Review Amber
    Phenotypes
    • Hereditary Paraganglioma-Pheochromocytoma Syndromes

    Green SDHC in Transplant Co-Morbidity Superpanel


    Level 2: Screening
    Version 0.18

    		0 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • Melbourne Genomics Health Alliance
    Phenotypes
    • Paragangliomas 3, MIM# 605373

    Green SDHC in Pituitary Tumour


    Level 2: Cancer Predisposition
    Version 1.1

    		1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • Expert Review
    • Expert list
    Phenotypes
    • Pituitary tumor, MONDO:0017611
    • Pituitary gland adenoma, MONDO:0006373
    • Hereditary pheochromocytoma-paraganglioma, MONDO:0017366
    • Pheochromocytoma/paraganglioma syndrome 3, MIM#605373

    Green SDHC in Paraganglioma_phaeochromocytoma


    Level 2: Cancer Predisposition
    Version 1.1

    		1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • Expert Review
    • Expert list
    Phenotypes
    • Paragangliomas 3, MONDO:0011544
    • Pheochromocytoma, MONDO:0008233
    • Hereditary pheochromocytoma-paraganglioma, MONDO:0017366
    • Pheochromocytoma/paraganglioma syndrome 3, MIM#605373

    Green SDHC in Kidney Cancer


    Level 2: Cancer Predisposition
    Version 1.1

    		1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • Expert Review
    • Expert list
    Phenotypes
    • Renal carcinoma, MONDO:0005206
    • Hereditary pheochromocytoma-paraganglioma, MONDO:0017366
    • Pheochromocytoma/paraganglioma syndrome 3, MIM#605373

    Green SDHC in Gastrointestinal Stromal Tumour


    Level 2: Cancer Predisposition
    Version 1.0

    		1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • Expert Review
    • Expert list
    Phenotypes
    • Gastrointestinal stromal tumor, MONDO:0011719
    • Hereditary pheochromocytoma-paraganglioma, MONDO:0017366
    • Pheochromocytoma/paraganglioma syndrome 3, MIM#605373