PanelApp (staging)
  1. Genes and Genomic Entities
  2. MET

MET

MET proto-oncogene, receptor tyrosine kinase
OMIM: 164860, ClinGen, DECIPHER

9 panels

Panel Reviews Mode of inheritance Details
9 panels

Amber MET in Arthrogryposis


Level 2: Neurology and neurodevelopmental disorders
Version 0.416

2 reviews MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Amber
  • Literature
Phenotypes
  • ?Arthrogryposis, distal, type 11 (MIM#620019), AD

Red MET in Autism


Level 2: Neurology and neurodevelopmental disorders
Version 0.205

1 review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Sources
  • Expert Review Red
  • Expert list
  • Victorian Clinical Genetics Services
Phenotypes
  • ?Deafness, autosomal recessive 97, OMIM #616705
  • {Osteofibrous dysplasia, susceptibility to}, OMIM #607278

Green MET in Mendeliome


Version 1.2302

1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Victorian Clinical Genetics Services
Phenotypes
  • Arthrogryposis, distal, type 11 (MIM#620019), AD
  • Renal cell carcinoma, papillary, 1, familial and somatic, MIM# 605074
  • Papillary renal cell carcinoma MONDO:0017884

Red MET in Deafness_IsolatedAndComplex


Level 2: Hearing and ear disorders
Version 1.210

1 review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Red
  • Expert list
Phenotypes
  • Deafness, autosomal recessive 97, MIM# 616705

Red MET in Intellectual disability syndromic and non-syndromic


Level 2: Neurology and neurodevelopmental disorders
Version 1.63

1 review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Sources
  • Expert Review Red
  • Expert list
Phenotypes
  • ?Deafness, autosomal recessive 97, OMIM #616705
  • {Osteofibrous dysplasia, susceptibility to}, OMIM #607278

Red MET in Lymphoedema_syndromic

Level 3: Lymphatic Disorders
Level 2: Cardiovascular disorders
Version 0.12

Component of the following Super Panels:

  • Vascular Malformations SuperPanel

    		•  0 reviews BOTH monoallelic and biallelic, autosomal or pseudoautosomal
    Sources
    • Expert list

    Amber MET in Vascular Malformations_Somatic


    Level 2: Cardiovascular disorders
    Version 1.14

    Component of the following Super Panels:

  • Vascular Malformations SuperPanel

    		•  1 review Other
    Sources
    • Expert Review Amber
    • Literature
    Phenotypes
    • lymphovenous malformation
    • overgrowth

    Green MET in Incidentalome_PREGEN_DRAFT


    Version 0.43

    		0 reviews Unknown
    Sources
    • NSW Health Pathology
    • Expert Review Green

    Green MET in Kidney Cancer


    Level 2: Cancer Predisposition
    Version 1.1

    		1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • Expert Review
    • Expert list
    Phenotypes
    • Renal carcinoma, MONDO:0005206
    • Papillary renal cell carcinoma, MONDO:0017884
    • Renal cell carcinoma, papillary, 1, familial, MIM#605074