PanelApp (staging)
  1. Genes and Genomic Entities
  2. KRT10

KRT10

keratin 10
OMIM: 148080, ClinGen, DECIPHER

7 panels

Panel Reviews Mode of inheritance Details
7 panels

Green KRT10 in Epidermolysis bullosa


Level 2: Dermatological disorders
Version 1.20

1 review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Literature
Phenotypes
  • Epidermolytic hyperkeratosis (MIM#113800)
  • Ichthyosis with confetti (MIM#609165)
  • Ichthyosis, cyclic, with epidermolytic hyperkeratosis (MIM#607602)

Green KRT10 in Ichthyosis


Level 2: Dermatological disorders
Version 1.11

1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Victorian Clinical Genetics Services
Phenotypes
  • Ichthyosis, cyclic, with epidermolytic hyperkeratosis, MIM# 607602
  • Ichthyosis with confetti, MIM# 609165

Green KRT10 in Mendeliome


Version 1.2302

1 review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Victorian Clinical Genetics Services
Phenotypes
  • Epidermolytic hyperkeratosis, MIM#113800
  • Ichthyosis with confetti, MIM#609165
  • Ichthyosis, cyclic, with epidermolytic hyperkeratosis, MIM#607602

Green KRT10 in Palmoplantar Keratoderma and Erythrokeratoderma


Level 2: Dermatological disorders
Version 0.132

0 reviews Unknown
Sources
  • Victorian Clinical Genetics Services
  • Expert Review Green

Green KRT10 in Mackenzie's Mission_Reproductive Carrier Screening


Level 2: Screening
Version 0.109

0 reviews BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Mackenzie's Mission
Phenotypes
  • Epidermolytic hyperkeratosis, 113800 (3), Autosomal recessive

Green KRT10 in Mosaic skin disorders


Level 2: Dermatological disorders
Version 1.12

Component of the following Super Panels:

  • Vascular Malformations SuperPanel

    		•  2 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • Genomics England PanelApp
    • NHS GMS
    Phenotypes
    • Epidermolytic hyperkeratosis
    • Pachyonychia congenita
    • Ichythosis with confetti
    • Palmoplantar keratoderma

    Green KRT10 in Prepair 1000+


    Level 2: Screening
    Version 1.1566

    		1 review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Mackenzie's Mission
    Phenotypes
    • Epidermolytic hyperkeratosis 2B, autosomal recessive MIM#620707
    • MONDO:0700245