PanelApp (staging)
  1. Genes and Genomic Entities
  2. KLF1

KLF1

Kruppel like factor 1
OMIM: 600599, ClinGen, DECIPHER

8 panels

Panel Reviews Mode of inheritance Details
8 panels

Green KLF1 in Bone Marrow Failure


Level 2: Haematological disorders
Version 1.112

Component of the following Super Panels:

  • Immunological disorders_SuperPanel

    		•  1 review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Victorian Clinical Genetics Services
    Phenotypes
    • Dyserythropoietic anaemia, congenital, type IVa, MIM# 613673
    • MONDO:0013355
    • Anaemia, congenital dyserythropoietic, type IVb, MIM#620969

    Green KLF1 in Hydrops fetalis


    Level 2: Dysmorphic and congenital abnormality syndromes
    Version 0.324

    		2 reviews BOTH monoallelic and biallelic, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Victorian Clinical Genetics Services
    Phenotypes
    • Congenital Dyserythropoietic Anemia Type IV, MIM#613673
    • Anaemia, congenital dyserythropoietic, type IVb, MIM#620969

    Green KLF1 in Mendeliome


    Version 1.2302

    		1 review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Victorian Clinical Genetics Services
    Phenotypes
    • Dyserythropoietic anaemia, congenital, type IV, MIM# 613673
    • MONDO:0013355
    • Anaemia, congenital dyserythropoietic, type IVb, MIM#620969

    Green KLF1 in Additional findings_Paediatric


    Level 2: Screening
    Version 0.278

    		1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • BabySeq Category C gene
    Phenotypes
    • Dyserythropoietic anaemia, congenital, type IV, MIM# 613673
    • MONDO:0013355

    Green KLF1 in Red cell disorders


    Level 2: Haematological disorders
    Version 1.29

    		1 review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Yorkshire and North East GLH
    • NHS GMS
    • Wessex and West Midlands GLH
    • North West GLH
    • London South GLH
    • Victorian Clinical Genetics Services
    Phenotypes
    • Dyserythropoietic anaemia, congenital, type IV, MIM# 613673
    • MONDO:0013355
    • Anaemia, congenital dyserythropoietic, type IVb, MIM#620969

    Green KLF1 in Fetal anomalies


    Version 1.313

    		3 reviews BOTH monoallelic and biallelic, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Genomics England PanelApp
    Phenotypes
    • Dyserythropoietic anaemia, congenital, type IV MIM#613673
    • Anaemia, congenital dyserythropoietic, type IVb, MIM#620969

    Green KLF1 in IBMDx study


    Version 0.33

    		1 review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • IBMDx Study
    • Victorian Clinical Genetics Services
    Phenotypes
    • Dyserythropoietic anaemia, congenital, type IV, MIM# 613673
    • MONDO:0013355
    • Anaemia, congenital dyserythropoietic, type IVb, MIM#620969

    Red KLF1 in BabyScreen+ newborn screening


    Level 2: Screening
    Version 1.116

    		1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Red
    • BabySeq Category C gene
    Phenotypes
    • Dyserythropoietic anaemia, congenital, type IV, MIM# 613673