INS

insulin
OMIM: 176730, ClinGen, DECIPHER

7 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 7 panels
Green INS in Mendeliome Version 1.2302	1 review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources Expert Review Green Victorian Clinical Genetics Services Phenotypes Diabetes mellitus, insulin-dependent, 2, MIM# 125852 Diabetes mellitus, permanent neonatal 4, MIM# 618858 Maturity-onset diabetes of the young, type 10, MIM# 613370
Red INS in Intellectual disability syndromic and non-syndromic Level 2: Neurology and neurodevelopmental disorders Version 1.63	1 review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Red Genetic Health Queensland Phenotypes Diabetes mellitus, permanent neonatal, MIM#606176
Green INS in Maturity-onset Diabetes of the Young Level 2: Endocrine disorders Version 1.21	2 reviews	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources Expert Review Green Royal Melbourne Hospital Victorian Clinical Genetics Services Phenotypes monogenic diabetes MONDO:0015967 Diabetes mellitus, insulin-dependent, 2, MIM# 125852 Diabetes mellitus, permanent neonatal 4, MIM# 618858 Maturity-onset diabetes of the young, type 10, MIM# 613370
Green INS in Monogenic Diabetes Level 2: Endocrine disorders Version 0.136 Component of the following Super Panels: Metabolic Disorders Superpanel	1 review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources Expert Review Green NHS GMS Phenotypes diabetes mellitus, permanent neonatal 4 MONDO:0030089 maturity-onset diabetes of the young type 10 MONDO:0013240
Green INS in Additional findings_Paediatric Level 2: Screening Version 0.278	1 review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Expert list Phenotypes Diabetes mellitus, permanent neonatal MIM# 618858Permanent neonatal diabetes mellitus-4 (PNDM4) is characterized by chronic hyperglycemia due to severe nonautoimmune insulin deficiency diagnosed in the first months of life
Green INS in BabyScreen+ newborn screening Level 2: Screening Version 1.116	1 review	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources Expert Review Green BeginNGS Expert list Phenotypes Diabetes mellitus, insulin-dependent, 2, MIM# 125852 Diabetes mellitus, permanent neonatal 4, MIM# 618858 Maturity-onset diabetes of the young, type 10, MIM# 613370 Tags for review treatable endocrine
Green INS in Transplant Co-Morbidity Superpanel Level 2: Screening Version 0.18	0 reviews	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources Expert Review Green NHS GMS Phenotypes Maturity Onset Diabetes of the Young (Dominant) Diabetes mellitus, type 1, 125852 Diabetes mellitus, insulin-dependent, 2, 125852 Transient Neonatal Diabetes, Dominant/Recessive MATURITY-ONSET DIABETES OF THE YOUNG, TYPE 10 Maturity-onset diabetes of the young, type 10, 613370 Diabetes mellitus, permanent neonatal, 606176 Hyperproinsulinemia, familial, with or without diabetes Permanent Neonatal diabetes mellitus Maturity Onset Diabetes of the Young MODY10