PanelApp (staging)
  1. Genes and Genomic Entities
  2. GLI2

GLI2

GLI family zinc finger 2
OMIM: 165230, ClinGen, DECIPHER

11 panels

Panel Reviews Mode of inheritance Details
11 panels

Green GLI2 in Holoprosencephaly and septo-optic dysplasia


Level 2: Neurology and neurodevelopmental disorders
Version 1.17

2 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Victorian Clinical Genetics Services
Phenotypes
  • Holoprosencephaly 9, MIM# 610829
  • MONDO:0012563

Green GLI2 in Mendeliome


Version 1.2302

2 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Victorian Clinical Genetics Services
Phenotypes
  • Culler-Jones syndrome, MIM#615849
  • Holoprosencephaly 9, MIM# 61082)

Green GLI2 in Polydactyly


Level 2: Dysmorphic and congenital abnormality syndromes
Version 0.281

Component of the following Super Panels:

  • Limb and Digital Malformations SuperPanel

    		•  1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Victorian Clinical Genetics Services
    • Expert Review Green

    Green GLI2 in Callosome


    Level 2: Neurology and neurodevelopmental disorders
    Version 0.540

    		0 reviews Unknown
    Sources
    • Victorian Clinical Genetics Services
    • Expert Review Green

    Green GLI2 in Intellectual disability syndromic and non-syndromic


    Level 2: Neurology and neurodevelopmental disorders
    Version 1.63

    		1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • Genetic Health Queensland
    Phenotypes
    • postaxial polydactyly-anterior pituitary anomalies-facial dysmorphism syndrome MONDO:0014369

    Green GLI2 in Pituitary hormone deficiency


    Level 2: Endocrine disorders
    Version 0.35

    		0 reviews MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
    Sources
    • Expert Review Green
    • Genomics England PanelApp
    Phenotypes
    • Culler-Jones syndrome (615849)
    • Holoprosencephaly 9 (610829)

    Red GLI2 in Additional findings_Paediatric


    Level 2: Screening
    Version 0.278

    		0 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Red
    • BabySeq Category C gene
    Phenotypes
    • Holoprosencephaly-9

    Green GLI2 in Clefting disorders

    Level 3: Dysmorphic disorders
    Level 2: Dysmorphic and congenital abnormality syndromes
    Version 0.260

    		1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • Expert Review
    Phenotypes
    • Culler-Jones syndrome, OMIM:615849
    • Holoprosencephaly 9, OMIM:610829

    Green GLI2 in Growth failure


    Version 1.76

    		1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • Genomics England PanelApp
    Phenotypes
    • Culler-Jones syndrome, MIM#615849
    • Holoprosencephaly 9, MIM# 61082

    Green GLI2 in Fetal anomalies


    Version 1.313

    		2 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • Genomics England PanelApp
    • Expert Review Green
    • Victorian Clinical Genetics Services
    Phenotypes
    • Culler-Jones syndrome, MIM#615849
    • Holoprosencephaly 9, MIM# 61082

    Red GLI2 in BabyScreen+ newborn screening


    Level 2: Screening
    Version 1.116

    		0 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • BabySeq Category C gene
    • Expert Review Red
    Phenotypes
    • Holoprosencephaly-9