PanelApp (staging)
  1. Genes and Genomic Entities
  2. GAD1

GAD1

glutamate decarboxylase 1
OMIM: 605363, ClinGen, DECIPHER

6 panels

Panel Reviews Mode of inheritance Details
6 panels

Red GAD1 in Cerebral Palsy


Level 2: Neurology and neurodevelopmental disorders
Version 1.389

1 review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Red
  • Victorian Clinical Genetics Services
Phenotypes
  • Cerebral palsy, spastic quadriplegic, 1, MIM#603513

Green GAD1 in Mendeliome


Version 1.2302

1 review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Victorian Clinical Genetics Services
  • Victorian Clinical Genetics Services
Phenotypes
  • Cerebral palsy, spastic quadriplegic, 1, MIM#603513
  • Developmental and epileptic encephalopathy 89, MIM# 619124

Green GAD1 in Genetic Epilepsy


Level 2: Neurology and neurodevelopmental disorders
Version 1.108

Component of the following Super Panels:

  • Progressive Neurological Conditions

    		•  1 review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Literature
    Phenotypes
    • Developmental and epileptic encephalopathy 89, MIM# 619124

    Green GAD1 in Intellectual disability syndromic and non-syndromic


    Level 2: Neurology and neurodevelopmental disorders
    Version 1.63

    		1 review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Genetic Health Queensland
    Phenotypes
    • Cerebral palsy, spastic quadriplegic, 1, MIM#603513
    • Developmental and epileptic encephalopathy 89, MIM# 619124

    Red GAD1 in Hereditary Spastic Paraplegia - paediatric


    Level 2: Neurology and neurodevelopmental disorders
    Version 1.86

    Component of the following Super Panels:

  • Hereditary Spastic Paraplegia Superpanel
  • Neuromuscular Superpanel
  • Progressive Neurological Conditions

    		•  1 review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Red
    • Royal Melbourne Hospital
    • Victorian Clinical Genetics Services
    • Victorian Clinical Genetics Services
    Phenotypes
    • Cerebralpalsy, spasticquadriplegic,1, 603513

    Green GAD1 in Aminoacidopathy


    Level 2: Metabolic disorders
    Version 1.133

    Component of the following Super Panels:

  • Metabolic Disorders Superpanel

    		•  1 review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • ClinGen
    Phenotypes
    • Developmental and epileptic encephalopathy 89, MIM# 619124