PanelApp (staging)
  1. Genes and Genomic Entities
  2. CD27

CD27

CD27 molecule
OMIM: 186711, ClinGen, DECIPHER

8 panels

Panel Reviews Mode of inheritance Details
8 panels

Green CD27 in Mendeliome


Version 1.2302

1 review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Victorian Clinical Genetics Services
Phenotypes
  • Lymphoproliferative syndrome 2
  • CD27-deficiency MIM# 615122
  • hepatosplenomegaly
  • reduced CD8+ T-cell function
  • lymphadenopathy
  • hepatosplenomegaly
  • fever
  • increased susceptibility to EBV infection
  • aplastic anaemia

Green CD27 in Combined Immunodeficiency


Level 2: Immunological disorders
Version 1.114

Component of the following Super Panels:

  • Immunological disorders_SuperPanel

    		•  1 review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Melbourne Genomics Health Alliance Immunology Flagship
    • Victorian Clinical Genetics Services
    Phenotypes
    • Lymphoproliferative syndrome 2
    • CD27-deficiency MIM# 615122
    • hepatosplenomegaly
    • reduced CD8+ T-cell function
    • lymphadenopathy
    • hepatosplenomegaly
    • fever
    • increased susceptibility to EBV infection
    • aplastic anaemia

    Green CD27 in Common Variable Immunodeficiency


    Level 2: Immunological disorders
    Version 1.12

    Component of the following Super Panels:

  • Immunological disorders_SuperPanel

    		•  1 review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Melbourne Genomics Health Alliance Immunology Flagship
    • Victorian Clinical Genetics Services
    Phenotypes
    • Lymphoproliferative syndrome 2
    • CD27-deficiency MIM# 615122
    • hepatosplenomegaly
    • reduced CD8+ T-cell function
    • lymphadenopathy
    • hepatosplenomegaly
    • fever
    • increased susceptibility to EBV infection
    • aplastic anaemia

    Green CD27 in Disorders of immune dysregulation


    Level 2: Immunological disorders
    Version 1.5

    Component of the following Super Panels:

  • Immunological disorders_SuperPanel

    		•  1 review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Expert list
    Phenotypes
    • Lymphoproliferative syndrome 2, MIM# 615122

    Green CD27 in Susceptibility to Viral Infections


    Level 2: Immunological disorders
    Version 0.131

    Component of the following Super Panels:

  • Immunological disorders_SuperPanel

    		•  1 review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Expert list
    Phenotypes
    • Lymphoproliferative syndrome 2, MIM# 615122
    • Host response to EBV

    Green CD27 in Mackenzie's Mission_Reproductive Carrier Screening


    Level 2: Screening
    Version 0.109

    		0 reviews BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Mackenzie's Mission
    Phenotypes
    • Lymphoproliferative syndrome 2, 615122 (3)

    Green CD27 in Prepair 1000+


    Level 2: Screening
    Version 1.1566

    		1 review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Mackenzie's Mission
    Phenotypes
    • Lymphoproliferative syndrome 2, MIM# 615122

    Green CD27 in BabyScreen+ newborn screening


    Level 2: Screening
    Version 1.116

    		1 review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Expert list
    Phenotypes
    • CD27-deficiency MIM# 615122
    Tags
    • treatable
    • immunological