PanelApp (staging)
  1. Genes and Genomic Entities
  2. ADAMTS10

ADAMTS10

ADAM metallopeptidase with thrombospondin type 1 motif 10
OMIM: 608990, ClinGen, DECIPHER

10 panels

Panel Reviews Mode of inheritance Details
10 panels

Green ADAMTS10 in Aortopathy_Connective Tissue Disorders


Level 2: Cardiovascular disorders
Version 1.86

1 review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Other
Phenotypes
  • Weill-Marchesani syndrome 1, recessive MIM#277600

Green ADAMTS10 in Arthrogryposis


Level 2: Neurology and neurodevelopmental disorders
Version 0.416

2 reviews Unknown
Sources
  • Expert Review Green
  • Expert list
  • Victorian Clinical Genetics Services
Phenotypes
  • Weill-Marchesani syndrome 1, recessive, MIM#277600

Green ADAMTS10 in Cataract


Level 2: Ophthalmological disorders
Version 0.373

0 reviews Unknown
Sources
  • Victorian Clinical Genetics Services
  • Expert Review Green

Green ADAMTS10 in Congenital Heart Defect


Level 2: Cardiovascular disorders
Version 0.430

1 review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Victorian Clinical Genetics Services
Phenotypes
  • Weill-Marchesani syndrome 1, recessive, MIM# 277600

Green ADAMTS10 in Glaucoma congenital


Level 2: Ophthalmological disorders
Version 1.9

1 review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Expert list
Phenotypes
  • Weill-Marchesani syndrome 1, recessive, MIM# 277600

Green ADAMTS10 in Mendeliome


Version 1.2302

1 review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Expert list
  • Victorian Clinical Genetics Services
Phenotypes
  • Weill-Marchesani syndrome 1, recessive, MIM#277600

Green ADAMTS10 in Intellectual disability syndromic and non-syndromic


Level 2: Neurology and neurodevelopmental disorders
Version 1.63

1 review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Genetic Health Queensland
Phenotypes
  • Weill-Marchesani syndrome 1, recessive, MIM#277600

Green ADAMTS10 in Skeletal dysplasia

Level 3: Skeletal dysplasias
Level 2: Skeletal disorders
Version 0.302

1 review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • NHS GMS
  • Expert list
  • Victorian Clinical Genetics Services
Phenotypes
  • Weill-Marchesani syndrome 1, recessive, 277600

Green ADAMTS10 in Hand and foot malformations


Level 2: Dysmorphic and congenital abnormality syndromes
Version 0.76

Component of the following Super Panels:

  • Limb and Digital Malformations SuperPanel

    		•  1 review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert list
    • Expert Review Green
    • Expert Review Green
    • Expert list
    • Victorian Clinical Genetics Services
    • Expert Review Green
    Phenotypes
    • Weill-Marchesani syndrome 1, recessive, 277600

    Green ADAMTS10 in Fetal anomalies


    Version 1.313

    		2 reviews BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Genomics England PanelApp
    • Genetic Health Queensland
    Phenotypes
    • Weill-Marchesani syndrome 1, recessive, MIM#277600