| Date | Panel | Item | Activity | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Sarcoma non-soft tissue v1.1 | Zornitza Stark Panel types changed to Victorian Clinical Genetics Services; Genetic Health Queensland; Cancer Germline; Adult Genetics Unit, Royal Adelaide Hospital | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v1.0 | Zornitza Stark promoted panel to version 1.0 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v0.16 | Zornitza Stark Panel status changed from internal to public | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v0.15 | WRN | Zornitza Stark Marked gene: WRN as ready | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v0.15 | WRN | Zornitza Stark Gene: wrn has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v0.15 | TP53 | Zornitza Stark Marked gene: TP53 as ready | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v0.15 | TP53 | Zornitza Stark Gene: tp53 has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v0.15 | RECQL4 | Zornitza Stark Marked gene: RECQL4 as ready | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v0.15 | RECQL4 | Zornitza Stark Gene: recql4 has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v0.15 | RB1 | Zornitza Stark Marked gene: RB1 as ready | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v0.15 | RB1 | Zornitza Stark Gene: rb1 has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v0.15 | EXT2 | Zornitza Stark Marked gene: EXT2 as ready | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v0.15 | EXT2 | Zornitza Stark Gene: ext2 has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v0.15 | EXT1 | Zornitza Stark Marked gene: EXT1 as ready | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v0.15 | EXT1 | Zornitza Stark Gene: ext1 has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v0.15 | BLM | Zornitza Stark Marked gene: BLM as ready | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v0.15 | BLM | Zornitza Stark Gene: blm has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v0.15 | TP53 | Chirag Patel Classified gene: TP53 as Green List (high evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v0.15 | TP53 | Chirag Patel Gene: tp53 has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v0.14 | RB1 | Chirag Patel Classified gene: RB1 as Green List (high evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v0.14 | RB1 | Chirag Patel Gene: rb1 has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v0.13 | EXT2 | Chirag Patel Classified gene: EXT2 as Green List (high evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v0.13 | EXT2 | Chirag Patel Gene: ext2 has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v0.12 | EXT1 | Chirag Patel Classified gene: EXT1 as Green List (high evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v0.12 | EXT1 | Chirag Patel Gene: ext1 has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v0.11 | WRN | Chirag Patel Classified gene: WRN as Green List (high evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v0.11 | WRN | Chirag Patel Gene: wrn has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v0.10 | RECQL4 | Chirag Patel Classified gene: RECQL4 as Green List (high evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v0.10 | RECQL4 | Chirag Patel Gene: recql4 has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v0.9 | BLM | Chirag Patel Classified gene: BLM as Green List (high evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v0.9 | BLM | Chirag Patel Gene: blm has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Sarcoma non-soft tissue v0.8 | TP53 |
Chirag Patel gene: TP53 was added gene: TP53 was added to Sarcoma non-soft tissue. Sources: Expert list,Expert Review Mode of inheritance for gene: TP53 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Phenotypes for gene: TP53 were set to Sarcoma, MONDO:0005089; Li-Fraumeni syndrome, MONDO:0018875; Li-Fraumeni syndrome, MIM#151623 Review for gene: TP53 was set to GREEN Added comment: ClinGen definitive. Non-soft-tissue sarcomas reported in condition. Consider possibility that an identified variant could represent ACE (aberrant clonal expansion), which can be due to clonal haematopoiesis of indeterminate potential (CHIP) or an occult hematologic malignancy, especially in older patients who have undergone prior chemotherapy (PMID: 36040522). Sources: Expert list, Expert Review |
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| Sarcoma non-soft tissue v0.7 | RB1 |
Chirag Patel gene: RB1 was added gene: RB1 was added to Sarcoma non-soft tissue. Sources: Expert list,Expert Review Mode of inheritance for gene: RB1 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Phenotypes for gene: RB1 were set to Sarcoma, MONDO:0005089; Retinoblastoma, MONDO:0008380; Retinoblastoma, MIM#180200 Review for gene: RB1 was set to GREEN Added comment: ClinGen definitive. Non-soft-tissue sarcomas reported in condition. Sources: Expert list, Expert Review |
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| Sarcoma non-soft tissue v0.6 | EXT2 |
Chirag Patel gene: EXT2 was added gene: EXT2 was added to Sarcoma non-soft tissue. Sources: Expert list,Expert Review Mode of inheritance for gene: EXT2 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Phenotypes for gene: EXT2 were set to Sarcoma, MONDO:0005089; Exostoses, multiple, type 2, MONDO:0007586; Exostoses, multiple, type 2, MIM#133701 Review for gene: EXT2 was set to GREEN Added comment: ClinGen definitive. Non-soft-tissue sarcomas reported in condition. Sources: Expert list, Expert Review |
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| Sarcoma non-soft tissue v0.5 | EXT1 |
Chirag Patel gene: EXT1 was added gene: EXT1 was added to Sarcoma non-soft tissue. Sources: Expert list,Expert Review Mode of inheritance for gene: EXT1 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Phenotypes for gene: EXT1 were set to Sarcoma, MONDO:0005089; Exostoses, multiple, type 1, MONDO:0007585; Exostoses, multiple, type 1, MIM#133700 Review for gene: EXT1 was set to GREEN Added comment: ClinGen definitive. Non-soft-tissue sarcomas reported in condition. Sources: Expert list, Expert Review |
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| Sarcoma non-soft tissue v0.4 | WRN |
Chirag Patel gene: WRN was added gene: WRN was added to Sarcoma non-soft tissue. Sources: Expert list,Expert Review Mode of inheritance for gene: WRN was set to BIALLELIC, autosomal or pseudoautosomal Phenotypes for gene: WRN were set to Sarcoma, MONDO:0005089; Werner syndrome, MONDO:0010196; Werner syndrome, MIM#277700 Review for gene: WRN was set to GREEN Added comment: ClinGen definitive. Non-soft-tissue sarcomas reported in condition. Sources: Expert list, Expert Review |
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| Sarcoma non-soft tissue v0.3 | RECQL4 |
Chirag Patel gene: RECQL4 was added gene: RECQL4 was added to Sarcoma non-soft tissue. Sources: Expert list,Expert Review Mode of inheritance for gene: RECQL4 was set to BIALLELIC, autosomal or pseudoautosomal Phenotypes for gene: RECQL4 were set to Sarcoma, MONDO:0005089; Rothmund-Thomson syndrome type 2, MONDO:0016369; Rothmund-Thomson syndrome, type 2, MIM#268400 Review for gene: RECQL4 was set to GREEN Added comment: ClinGen definitive. Non-soft-tissue sarcomas reported in condition. Sources: Expert list, Expert Review |
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| Sarcoma non-soft tissue v0.2 | BLM |
Chirag Patel gene: BLM was added gene: BLM was added to Sarcoma non-soft tissue. Sources: Expert list,Expert Review Mode of inheritance for gene: BLM was set to BIALLELIC, autosomal or pseudoautosomal Phenotypes for gene: BLM were set to Sarcoma, MONDO:0005089; Bloom syndrome, MONDO:0008876; Bloom syndrome, MIM#210900 Review for gene: BLM was set to GREEN Added comment: ClinGen definitive. Non-soft-tissue sarcomas reported in condition. Sources: Expert list, Expert Review |
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| Sarcoma non-soft tissue v0.0 |
Chirag Patel Added Panel Sarcoma non-soft tissue Set panel types to: Cancer Germline |
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