Activity
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7 actions
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| Susceptibility to Viral Infections v0.128 | TMEFF1 | Zornitza Stark Marked gene: TMEFF1 as ready | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Susceptibility to Viral Infections v0.128 | TMEFF1 | Zornitza Stark Gene: tmeff1 has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Susceptibility to Viral Infections v0.128 | TMEFF1 | Zornitza Stark Phenotypes for gene: TMEFF1 were changed from hsv encephalitis to Hereditary susceptibility to infections, MONDO:0015979, TMEFF1-related; HSV encephalitis | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Susceptibility to Viral Infections v0.127 | TMEFF1 | Zornitza Stark Classified gene: TMEFF1 as Green List (high evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Susceptibility to Viral Infections v0.127 | TMEFF1 | Zornitza Stark Gene: tmeff1 has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Susceptibility to Viral Infections v0.126 | TMEFF1 | Zornitza Stark reviewed gene: TMEFF1: Rating: GREEN; Mode of pathogenicity: None; Publications: ; Phenotypes: Hereditary susceptibility to infections, MONDO:0015979, TMEFF1-related; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Susceptibility to Viral Infections v0.126 | TMEFF1 |
Peter McNaughton gene: TMEFF1 was added gene: TMEFF1 was added to Susceptibility to Viral Infections. Sources: Literature Mode of inheritance for gene: TMEFF1 was set to BIALLELIC, autosomal or pseudoautosomal Publications for gene: TMEFF1 were set to PMID: 39048830 Phenotypes for gene: TMEFF1 were set to hsv encephalitis Review for gene: TMEFF1 was set to GREEN Added comment: 2 unrelated patients with severe HSV encephalitis. Functional validation showing that human TMEFF1 encodes a type I IFN-independent, cortical neuron- and CNS-intrinsic restriction factor that is effective against HSV-1 that operates by impairing the entry of HSV-1 into cortical neurons. Sources: Literature |
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