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Defects of intrinsic and innate immunity v1.15 TLR8 Bryony Thompson Marked gene: TLR8 as ready
Defects of intrinsic and innate immunity v1.15 TLR8 Bryony Thompson Gene: tlr8 has been classified as Green List (High Evidence).
Defects of intrinsic and innate immunity v1.15 TLR8 Bryony Thompson Classified gene: TLR8 as Green List (high evidence)
Defects of intrinsic and innate immunity v1.15 TLR8 Bryony Thompson Gene: tlr8 has been classified as Green List (High Evidence).
Defects of intrinsic and innate immunity v1.14 TLR8 Bryony Thompson gene: TLR8 was added
gene: TLR8 was added to Defects of innate immunity. Sources: Expert list
Mode of inheritance for gene: TLR8 was set to X-LINKED: hemizygous mutation in males, biallelic mutations in females
Publications for gene: TLR8 were set to 33512449; 34981838
Phenotypes for gene: TLR8 were set to Immunodeficiency 98 with autoinflammation, X-linked, MIM# 301078
Mode of pathogenicity for gene: TLR8 was set to Other
Review for gene: TLR8 was set to GREEN
gene: TLR8 was marked as current diagnostic
Added comment: TLR signaling pathway deficiency with bacterial susceptibility. Mainly mosaic and gain of function is mechanism of disease
Sources: Expert list