| Date | Panel | Item | Activity | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Defects of intrinsic and innate immunity v1.15 | TLR8 | Bryony Thompson Marked gene: TLR8 as ready | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Defects of intrinsic and innate immunity v1.15 | TLR8 | Bryony Thompson Gene: tlr8 has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Defects of intrinsic and innate immunity v1.15 | TLR8 | Bryony Thompson Classified gene: TLR8 as Green List (high evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Defects of intrinsic and innate immunity v1.15 | TLR8 | Bryony Thompson Gene: tlr8 has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Defects of intrinsic and innate immunity v1.14 | TLR8 |
Bryony Thompson gene: TLR8 was added gene: TLR8 was added to Defects of innate immunity. Sources: Expert list Mode of inheritance for gene: TLR8 was set to X-LINKED: hemizygous mutation in males, biallelic mutations in females Publications for gene: TLR8 were set to 33512449; 34981838 Phenotypes for gene: TLR8 were set to Immunodeficiency 98 with autoinflammation, X-linked, MIM# 301078 Mode of pathogenicity for gene: TLR8 was set to Other Review for gene: TLR8 was set to GREEN gene: TLR8 was marked as current diagnostic Added comment: TLR signaling pathway deficiency with bacterial susceptibility. Mainly mosaic and gain of function is mechanism of disease Sources: Expert list |
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