Activity

Filter

Cancel
Date Panel Item Activity
5 actions
Defects of intrinsic and innate immunity v0.181 TLR7 Bryony Thompson Marked gene: TLR7 as ready
Defects of intrinsic and innate immunity v0.181 TLR7 Bryony Thompson Gene: tlr7 has been classified as Green List (High Evidence).
Defects of intrinsic and innate immunity v0.181 TLR7 Bryony Thompson Classified gene: TLR7 as Green List (high evidence)
Defects of intrinsic and innate immunity v0.181 TLR7 Bryony Thompson Gene: tlr7 has been classified as Green List (High Evidence).
Defects of intrinsic and innate immunity v0.180 TLR7 Bryony Thompson gene: TLR7 was added
gene: TLR7 was added to Defects of innate immunity. Sources: Expert list
Mode of inheritance for gene: TLR7 was set to X-LINKED: hemizygous mutation in males, biallelic mutations in females
Publications for gene: TLR7 were set to 32706371; 35708626
Phenotypes for gene: TLR7 were set to Immunodeficiency 74, COVID-19-related, X-linked MONDO:0026767
Review for gene: TLR7 was set to GREEN
Added comment: At least 7 families with affected hemizygous males. IUIS IEI committee categorise gene under Predisposition to Severe Viral Infection.
Sources: Expert list