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Fetal anomalies v0.4700 NCAPD2 Zornitza Stark Marked gene: NCAPD2 as ready
Fetal anomalies v0.4700 NCAPD2 Zornitza Stark Gene: ncapd2 has been classified as Green List (High Evidence).
Fetal anomalies v0.4700 NCAPD2 Zornitza Stark Classified gene: NCAPD2 as Green List (high evidence)
Fetal anomalies v0.4700 NCAPD2 Zornitza Stark Gene: ncapd2 has been classified as Green List (High Evidence).
Fetal anomalies v0.4699 NCAPD2 Zornitza Stark gene: NCAPD2 was added
gene: NCAPD2 was added to Fetal anomalies. Sources: Expert Review
Mode of inheritance for gene: NCAPD2 was set to BIALLELIC, autosomal or pseudoautosomal
Publications for gene: NCAPD2 were set to 31056748; 27737959; 28097321
Phenotypes for gene: NCAPD2 were set to Microcephaly 21, primary, autosomal recessive; OMIM #617983
Review for gene: NCAPD2 was set to GREEN
Added comment: Three families reported: 1 family with 2 sibs with microcephaly and ID, and homozygous NCAPD2 mutation, which segregated with disease. No functional evidence. 1 family with 1 affected and homozygous NCAPD2 mutation, which segregated with disease. Patient fibroblasts showed impaired chromosome segregation and abnormal recovery from mitotic condensation compared to controls. 1 family with 2 sibs with microcephaly, growth retardation, and ID, and homozygous NCAPD2 mutation, which segregated with disease. Functional studies of the variants and studies of patient cells were not performed.

IUGR reported.
Sources: Expert Review