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Primary Ovarian Insufficiency_Premature Ovarian Failure v0.339 MGA Zornitza Stark Marked gene: MGA as ready
Primary Ovarian Insufficiency_Premature Ovarian Failure v0.339 MGA Zornitza Stark Gene: mga has been classified as Amber List (Moderate Evidence).
Primary Ovarian Insufficiency_Premature Ovarian Failure v0.339 MGA Zornitza Stark Classified gene: MGA as Amber List (moderate evidence)
Primary Ovarian Insufficiency_Premature Ovarian Failure v0.339 MGA Zornitza Stark Gene: mga has been classified as Amber List (Moderate Evidence).
Primary Ovarian Insufficiency_Premature Ovarian Failure v0.338 MGA Zornitza Stark gene: MGA was added
gene: MGA was added to Primary Ovarian Insufficiency_Premature Ovarian Failure. Sources: Literature
Mode of inheritance for gene: MGA was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Publications for gene: MGA were set to 39545409
Phenotypes for gene: MGA were set to Premature ovarian failure 26, MIM# 621065
Review for gene: MGA was set to AMBER
Added comment: Association with POF: LoF variants enriched in a large POF cohort. Familial testing in a small number of families performed. Mouse model supportive. Also borderline Amber/Green. Amber rating until phenotypes and mechanisms of disease for these two associations clarified.
Sources: Literature