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Defects of intrinsic and innate immunity v0.165 IRF4 Bryony Thompson Classified gene: IRF4 as Green List (high evidence)
Defects of intrinsic and innate immunity v0.165 IRF4 Bryony Thompson Gene: irf4 has been classified as Green List (High Evidence).
Defects of intrinsic and innate immunity v0.164 IRF4 Bryony Thompson gene: IRF4 was added
gene: IRF4 was added to Defects of innate immunity. Sources: Expert list
Mode of inheritance for gene: IRF4 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Publications for gene: IRF4 were set to 36662884, 36917008, 29537367, 29408330
Phenotypes for gene: IRF4 were set to combined immunodeficiency MONDO:0015131
Review for gene: IRF4 was set to GREEN
gene: IRF4 was marked as current diagnostic
Added comment: IRF4 is a transcription factor involved in the regulation of innate immunity. Definitive gene-disease association - https://search.clinicalgenome.org/CCID:008358. The IUIS IEI committee categorises this gene as other inborn errors of immunity related to leukocytes.
Sources: Expert list