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  3. FGF10
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Craniosynostosis

Gene: FGF10

Amber List (moderate evidence)
FGF10 (fibroblast growth factor 10)
EnsemblGeneIds (GRCh38): ENSG00000070193
EnsemblGeneIds (GRCh37): ENSG00000070193
OMIM: 602115, Gene2Phenotype
FGF10 is in 8 panels

2 reviews

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

I don't know

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Phenotypes
Craniosynostosis

Publications

Created: 3 Jul 2020, 3:22 a.m.
Last Modified: 3 Jul 2020, 3:22 a.m.
Panel version: 1.0

Tiong Tan (Victorian Clinical Genetics Services)

Comment on list classification: Two unrelated individuals in large craniosynostosis cohort with pathogenic variants in FGF10.
Created: 9 Jun 2020, 12:27 a.m. | Last Modified: 9 Jun 2020, 12:27 a.m.
Panel Version: 0.38
Created: 9 Jun 2020, 12:27 a.m.
Last Modified: 9 Jun 2020, 12:27 a.m.
Panel version: 0.38

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Amber
  • Victorian Clinical Genetics Services
Phenotypes
  • Craniosynostosis
OMIM
602115
Clinvar variants
Variants in FGF10
Penetrance
None
Publications
Panels with this gene

History Filter Activity

23 Oct 2020, Gel status: 2

Set Phenotypes

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Phenotypes for gene: FGF10 were changed from to Craniosynostosis

3 Jul 2020, Gel status: 2

Set mode of inheritance

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Mode of inheritance for gene: FGF10 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

9 Jun 2020, Gel status: 2

Set publications

Tiong Tan (Victorian Clinical Genetics Services)

Publications for gene: FGF10 were set to

9 Jun 2020, Gel status: 2

Entity classified by Genomics England curator

Tiong Tan (Victorian Clinical Genetics Services)

Gene: fgf10 has been classified as Amber List (Moderate Evidence).

9 Jun 2020, Gel status: 2

Entity classified by Genomics England curator

Tiong Tan (Victorian Clinical Genetics Services)

Gene: fgf10 has been classified as Amber List (Moderate Evidence).

17 Nov 2019, Gel status: 3

Created, Added New Source, Set mode of inheritance

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

gene: FGF10 was added gene: FGF10 was added to Craniosynostosis_VCGS. Sources: Expert Review Green,Victorian Clinical Genetics Services Mode of inheritance for gene: FGF10 was set to Unknown