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  2. Ciliary Dyskinesia
  3. NEK10
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Ciliary Dyskinesia

Gene: NEK10

Green List (high evidence)
NEK10 (NIMA related kinase 10)
EnsemblGeneIds (GRCh38): ENSG00000163491
EnsemblGeneIds (GRCh37): ENSG00000163491
NEK10 is in 3 panels

1 review

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Green List (high evidence)

Nine individuals from 5 unrelated families, some functional data.
Sources: NHS GMS
Created: 1 Apr 2020, 10:02 a.m.

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Phenotypes
Ciliary dyskinesia, primary, 44, MIM# 618781

Publications

Variants in this GENE are reported as part of current diagnostic practice

Created: 1 Apr 2020, 10:02 a.m.

Panel version: 1.13

Details

Mode of Inheritance
BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • NHS GMS
Phenotypes
  • Ciliary dyskinesia, primary, 44, MIM# 618781
  • Bronchiectasis
Clinvar variants
Variants in NEK10
Penetrance
None
Publications
Panels with this gene

History Filter Activity

6 Dec 2021, Gel status: 3

Set Phenotypes

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Phenotypes for gene: NEK10 were changed from Primary ciliary dyskinesia; bronchiectasis to Ciliary dyskinesia, primary, 44, MIM# 618781; Bronchiectasis

1 Apr 2020, Gel status: 3

Entity classified by Genomics England curator

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Gene: nek10 has been classified as Green List (High Evidence).

1 Apr 2020, Gel status: 3

Set Phenotypes

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Phenotypes for gene: NEK10 were changed from to Primary ciliary dyskinesia; bronchiectasis

1 Apr 2020, Gel status: 3

Entity classified by Genomics England curator

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Gene: nek10 has been classified as Green List (High Evidence).

1 Apr 2020, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set publications

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

gene: NEK10 was added gene: NEK10 was added to Ciliary Dyskinesia. Sources: NHS GMS Mode of inheritance for gene: NEK10 was set to BIALLELIC, autosomal or pseudoautosomal Publications for gene: NEK10 were set to 31959991 Review for gene: NEK10 was set to GREEN gene: NEK10 was marked as current diagnostic