1. Panels
  2. Cataract
  3. FYCO1
Genes in panel
Prev Next
STRs in panel
Prev Next
Regions in panel
Prev Next

Cataract

Gene: FYCO1

Green List (high evidence)
FYCO1 (FYVE and coiled-coil domain containing 1)
EnsemblGeneIds (GRCh38): ENSG00000163820
EnsemblGeneIds (GRCh37): ENSG00000163820
OMIM: 607182, Gene2Phenotype
FYCO1 is in 5 panels

1 review

Teresa Zhao (Victorian Clinical Genetics Services)

Green List (high evidence)

Well reported gene-disease association. Multiple variants (missense, nonsense, frameshift and splice variants) reported.
Created: 5 Jul 2021, 5:53 a.m. | Last Modified: 5 Jul 2021, 5:53 a.m.
Panel Version: 0.279

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Phenotypes
Cataract 18 (MIN#610019) AR

Publications

Created: 5 Jul 2021, 5:53 a.m.
Last Modified: 5 Jul 2021, 5:53 a.m.
Panel version: 0.279

Details

Mode of Inheritance
BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Victorian Clinical Genetics Services
Phenotypes
  • Cataract 18, MIM#610019
OMIM
607182
Clinvar variants
Variants in FYCO1
Penetrance
None
Publications
Panels with this gene

History Filter Activity

8 Jul 2021, Gel status: 3

Entity classified by Genomics England curator

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Gene: fyco1 has been classified as Green List (High Evidence).

8 Jul 2021, Gel status: 3

Set Phenotypes

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Phenotypes for gene: FYCO1 were changed from to Cataract 18, MIM#610019

8 Jul 2021, Gel status: 3

Set publications

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Publications for gene: FYCO1 were set to

8 Jul 2021, Gel status: 3

Set mode of inheritance

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Mode of inheritance for gene: FYCO1 was changed from BIALLELIC, autosomal or pseudoautosomal to BIALLELIC, autosomal or pseudoautosomal

8 Jul 2021, Gel status: 3

Set mode of inheritance

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Mode of inheritance for gene: FYCO1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal

17 Nov 2019, Gel status: 3

Created, Added New Source, Set mode of inheritance

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

gene: FYCO1 was added gene: FYCO1 was added to Cataract_VCGS. Sources: Expert Review Green,Victorian Clinical Genetics Services Mode of inheritance for gene: FYCO1 was set to Unknown