1. Panels
  2. Bone Marrow Failure
  3. PALB2
STRs in panel
Prev Next
Regions in panel
Prev Next

Bone Marrow Failure

Gene: PALB2

Green List (high evidence)
PALB2 (partner and localizer of BRCA2)
EnsemblGeneIds (GRCh38): ENSG00000083093
EnsemblGeneIds (GRCh37): ENSG00000083093
OMIM: 610355, Gene2Phenotype
PALB2 is in 18 panels

1 review

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Green List (high evidence)

Established gene-disease association.
Created: 23 Apr 2021, 6:54 a.m. | Last Modified: 23 Apr 2021, 6:54 a.m.
Panel Version: 0.136

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Phenotypes
Fanconi anaemia, complementation group N, MIM# 610832

Created: 23 Apr 2021, 6:54 a.m.
Last Modified: 23 Apr 2021, 6:54 a.m.
Panel version: Imported from Chromosome Breakage Disorders panel version 0.136

History Filter Activity

17 Jun 2021, Gel status: 3

Entity classified by Genomics England curator

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Gene: palb2 has been classified as Green List (High Evidence).

17 Jun 2021, Gel status: 3

Set Phenotypes

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Phenotypes for gene: PALB2 were changed from to Fanconi anaemia, complementation group N, MIM# 610832

17 Jun 2021, Gel status: 3

Set mode of inheritance

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Mode of inheritance for gene: PALB2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal

17 Nov 2019, Gel status: 3

Created, Added New Source, Set mode of inheritance

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

gene: PALB2 was added gene: PALB2 was added to Bone Marrow Failure_VCGS. Sources: Expert Review Green,Victorian Clinical Genetics Services Mode of inheritance for gene: PALB2 was set to Unknown