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  2. Ovarian Cancer
  3. RAD51D
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Ovarian Cancer

Gene: RAD51D

Green List (high evidence)
RAD51D (RAD51 paralog D)
EnsemblGeneIds (GRCh38): ENSG00000185379
EnsemblGeneIds (GRCh37): ENSG00000185379
OMIM: 602954, Gene2Phenotype
RAD51D is in 4 panels

1 review

Chirag Patel (Genetic Health Queensland)

Green List (high evidence)

ClinGen definitive. Ovarian cancers reported in condition.
Sources: Expert list, Expert Review
Created: 18 Sep 2024, 11:47 p.m.

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Phenotypes
Ovarian cancer, MONDO:0008170; RAD51D-related cancer predisposition, MONDO:0700274; Breast-ovarian cancer, familial, susceptibility to, 4, MONDO:0013669; Breast-ovarian cancer, familial, susceptibility to, 4, MIM#614291

Created: 18 Sep 2024, 11:47 p.m.

Panel version: 0.15

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Expert Review
  • Expert list
Phenotypes
  • Ovarian cancer, MONDO:0008170
  • RAD51D-related cancer predisposition, MONDO:0700274
  • Breast-ovarian cancer, familial, susceptibility to, 4, MONDO:0013669
  • Breast-ovarian cancer, familial, susceptibility to, 4, MIM#614291
OMIM
602954
Clinvar variants
Variants in RAD51D
Penetrance
None
Panels with this gene

History Filter Activity

9 Oct 2024, Gel status: 3

Entity classified by Genomics England curator

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Gene: rad51d has been classified as Green List (High Evidence).

18 Sep 2024, Gel status: 3

Entity classified by Genomics England curator

Chirag Patel (Genetic Health Queensland)

Gene: rad51d has been classified as Green List (High Evidence).

18 Sep 2024, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set Phenotypes

Chirag Patel (Genetic Health Queensland)

gene: RAD51D was added gene: RAD51D was added to Ovarian Cancer. Sources: Expert list,Expert Review Mode of inheritance for gene: RAD51D was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Phenotypes for gene: RAD51D were set to Ovarian cancer, MONDO:0008170; RAD51D-related cancer predisposition, MONDO:0700274; Breast-ovarian cancer, familial, susceptibility to, 4, MONDO:0013669; Breast-ovarian cancer, familial, susceptibility to, 4, MIM#614291 Review for gene: RAD51D was set to GREEN