Wilms Tumour
Gene: NYNRINEnsemblGeneIds (GRCh38): ENSG00000205978
EnsemblGeneIds (GRCh37): ENSG00000205978
NYNRIN is in 3 panels
1 review
Chirag Patel (Genetic Health Queensland)
Some evidence for gene-disease association for Wilms tumour. Three cases of biallelic truncating variants associated with sporadic Wilms tumour.
Sources: Expert list, Expert Review, LiteratureCreated: 26 Sep 2024, 1:37 a.m.
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Wilms tumor, MONDO:0006058; Wilms tumour, no MIM#
Publications
- PMID: 30885698
Details
- Mode of Inheritance
- BIALLELIC, autosomal or pseudoautosomal
- Sources
-
- Expert Review Amber
- Literature
- Expert Review
- Expert list
- Phenotypes
-
- Wilms tumor, MONDO:0006058
- Wilms tumour, no MIM#
- Clinvar variants
- Variants in NYNRIN
- Penetrance
- None
- Publications
-
- PMID: 30885698
- Panels with this gene
History Filter Activity
Entity classified by Genomics England curator
Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)Gene: nynrin has been classified as Amber List (Moderate Evidence).
Entity classified by Genomics England curator
Chirag Patel (Genetic Health Queensland)Gene: nynrin has been classified as Amber List (Moderate Evidence).
Created, Added New Source, Set mode of inheritance, Set publications, Set Phenotypes
Chirag Patel (Genetic Health Queensland)gene: NYNRIN was added gene: NYNRIN was added to Wilms Tumour. Sources: Expert list,Expert Review,Literature Mode of inheritance for gene: NYNRIN was set to BIALLELIC, autosomal or pseudoautosomal Publications for gene: NYNRIN were set to PMID: 30885698 Phenotypes for gene: NYNRIN were set to Wilms tumor, MONDO:0006058; Wilms tumour, no MIM# Review for gene: NYNRIN was set to AMBER