Entity Name	Entity type	Gene Symbol	Sources(; separated)	Level4	Level3	Level2	Model_Of_Inheritance	Phenotypes	Omim	Orphanet	HPO	Publications	Description	Flagged	GEL_Status	UserRatings_Green_amber_red	version	ready	Mode of pathogenicity	EnsemblId(GRch37)	EnsemblId(GRch38)	HGNC	Position Chromosome	Position GRCh37 Start	Position GRCh37 End	Position GRCh38 Start	Position GRCh38 End	STR Repeated Sequence	STR Normal Repeats	STR Pathogenic Repeats	Region Haploinsufficiency Score	Region Triplosensitivity Score	Region Required Overlap Percentage	Region Variant Type	Region Verbose Name
FH	gene	FH	Expert list;Expert Review;Expert Review Green	Paraganglioma_phaeochromocytoma		Cancer Predisposition	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Paraganglioma, MONDO:0000448;Pheochromocytoma, MONDO:0008233;Hereditary leiomyomatosis and renal cell cancer, MONDO:0007888;Leiomyomatosis and renal cell cancer, MIM#150800			Paraganglioma;HP:0002668; Phaeochromocytoma;HP:0002666			False	3	100;0;0	1.1	True		ENSG00000091483	ENSG00000091483	HGNC:3700													
MAX	gene	MAX	Expert list;Expert Review;Expert Review Green	Paraganglioma_phaeochromocytoma		Cancer Predisposition	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Paraganglioma, MONDO:0000448;Pheochromocytoma, MONDO:0008233;Hereditary pheochromocytoma-paraganglioma, MONDO:0017366;Pheochromocytoma, susceptibility to, MIM#171300			Paraganglioma;HP:0002668; Phaeochromocytoma;HP:0002666			False	3	100;0;0	1.1	True		ENSG00000125952	ENSG00000125952	HGNC:6913													
MEN1	gene	MEN1	Expert list;Expert Review;Expert Review Green	Paraganglioma_phaeochromocytoma		Cancer Predisposition	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Paraganglioma, MONDO:0000448;Pheochromocytoma, MONDO:0008233;Multiple endocrine neoplasia type 1, MONDO:0007540;Multiple endocrine neoplasia, type 1, MIM#131100			Paraganglioma;HP:0002668; Phaeochromocytoma;HP:0002666			False	3	100;0;0	1.1	True		ENSG00000133895	ENSG00000133895	HGNC:7010													
NF1	gene	NF1	Expert list;Expert Review;Expert Review Green	Paraganglioma_phaeochromocytoma		Cancer Predisposition	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Paraganglioma, MONDO:0000448;Pheochromocytoma, MONDO:0008233;Neurofibromatosis type 1, MONDO:0018975;Neurofibromatosis, type 1, MIM#162200			Paraganglioma;HP:0002668; Phaeochromocytoma;HP:0002666			False	3	100;0;0	1.1	True		ENSG00000196712	ENSG00000196712	HGNC:7765													
RET	gene	RET	Expert list;Expert Review;Expert Review Green	Paraganglioma_phaeochromocytoma		Cancer Predisposition	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Paraganglioma, MONDO:0000448;Pheochromocytoma, MONDO:0008233;Multiple endocrine neoplasia type 2A, MONDO:0008234;Multiple endocrine neoplasia type 2B, MONDO:0008082;Multiple endocrine neoplasia, type 2A, MIM#171400;Multiple endocrine neoplasia, type 2B, MIM#162300;Pheochromocytoma, MIM#171300;Medullary thyroid carcinoma, MIM#155240;Pheochromocytoma, susceptibility to, MIM#171300			Paraganglioma;HP:0002668; Phaeochromocytoma;HP:0002666			False	3	100;0;0	1.1	True	Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments	ENSG00000165731	ENSG00000165731	HGNC:9967													
SDHA	gene	SDHA	Expert list;Expert Review;Expert Review Green	Paraganglioma_phaeochromocytoma		Cancer Predisposition	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Paragangliomas 5, MONDO:0013602;Pheochromocytoma, MONDO:0008233;Hereditary pheochromocytoma-paraganglioma, MONDO:0017366;Pheochromocytoma/paraganglioma syndrome 5, MIM#614165			Paraganglioma;HP:0002668; Phaeochromocytoma;HP:0002666			False	3	100;0;0	1.1	True		ENSG00000073578	ENSG00000073578	HGNC:10680													
SDHAF2	gene	SDHAF2	Expert list;Expert Review;Expert Review Green	Paraganglioma_phaeochromocytoma		Cancer Predisposition	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Paragangliomas 2, MONDO:0011121;Pheochromocytoma, MONDO:0008233;Hereditary pheochromocytoma-paraganglioma, MONDO:0017366;Pheochromocytoma/paraganglioma syndrome 2, MIM#601650			Paraganglioma;HP:0002668; Phaeochromocytoma;HP:0002666			False	3	100;0;0	1.1	True		ENSG00000167985	ENSG00000167985	HGNC:26034													
SDHB	gene	SDHB	Expert list;Expert Review;Expert Review Green	Paraganglioma_phaeochromocytoma		Cancer Predisposition	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Paragangliomas 4, MONDO:0007273;Pheochromocytoma, MONDO:0008233;Hereditary pheochromocytoma-paraganglioma, MONDO:0017366;Pheochromocytoma/paraganglioma syndrome 4, MIM#115310			Paraganglioma;HP:0002668; Phaeochromocytoma;HP:0002666			False	3	100;0;0	1.1	True		ENSG00000117118	ENSG00000117118	HGNC:10681													
SDHC	gene	SDHC	Expert list;Expert Review;Expert Review Green	Paraganglioma_phaeochromocytoma		Cancer Predisposition	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Paragangliomas 3, MONDO:0011544;Pheochromocytoma, MONDO:0008233;Hereditary pheochromocytoma-paraganglioma, MONDO:0017366;Pheochromocytoma/paraganglioma syndrome 3, MIM#605373			Paraganglioma;HP:0002668; Phaeochromocytoma;HP:0002666			False	3	100;0;0	1.1	True		ENSG00000143252	ENSG00000143252	HGNC:10682													
SDHD	gene	SDHD	Expert list;Expert Review;Expert Review Green	Paraganglioma_phaeochromocytoma		Cancer Predisposition	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Paragangliomas 1, MONDO:0008192;Pheochromocytoma, MONDO:0008233;Hereditary pheochromocytoma-paraganglioma, MONDO:0017366;Pheochromocytoma/paraganglioma syndrome 1, MIM#168000			Paraganglioma;HP:0002668; Phaeochromocytoma;HP:0002666			False	3	100;0;0	1.1	True		ENSG00000204370	ENSG00000204370	HGNC:10683													
TMEM127	gene	TMEM127	Expert list;Expert Review;Expert Review Green	Paraganglioma_phaeochromocytoma		Cancer Predisposition	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Paraganglioma, MONDO:0000448;Pheochromocytoma, MONDO:0008233;Hereditary pheochromocytoma-paraganglioma, MONDO:0017366;Pheochromocytoma, susceptibility to, MIM#171300			Paraganglioma;HP:0002668; Phaeochromocytoma;HP:0002666			False	3	100;0;0	1.1	True		ENSG00000135956	ENSG00000135956	HGNC:26038													
VHL	gene	VHL	Expert list;Expert Review;Expert Review Green	Paraganglioma_phaeochromocytoma		Cancer Predisposition	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Paraganglioma, MONDO:0000448;Pheochromocytoma, MONDO:0008233;Von Hippel-Lindau disease, MONDO:0008667;von Hippel-Lindau syndrome, MIM#193300;Pheochromocytoma, susceptibility to, MIM#171300			Paraganglioma;HP:0002668; Phaeochromocytoma;HP:0002666			False	3	100;0;0	1.1	True		ENSG00000134086	ENSG00000134086	HGNC:12687