Entity Name	Entity type	Gene Symbol	Sources(; separated)	Level4	Level3	Level2	Model_Of_Inheritance	Phenotypes	Omim	Orphanet	HPO	Publications	Description	Flagged	GEL_Status	UserRatings_Green_amber_red	version	ready	Mode of pathogenicity	EnsemblId(GRch37)	EnsemblId(GRch38)	HGNC	Position Chromosome	Position GRCh37 Start	Position GRCh37 End	Position GRCh38 Start	Position GRCh38 End	STR Repeated Sequence	STR Normal Repeats	STR Pathogenic Repeats	Region Haploinsufficiency Score	Region Triplosensitivity Score	Region Required Overlap Percentage	Region Variant Type	Region Verbose Name
COL3A1	gene	COL3A1	Expert Review Green;Literature	Spontaneous coronary artery dissection		Cardiovascular disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	"Ehlers-Danlos syndrome, vascular type	MIM#130050"				30071989;39130004;32897753;35234813		False	3	100;0;0	0.56	True		ENSG00000168542	ENSG00000168542	HGNC:2201													
COL4A1	gene	COL4A1	Expert Review Green;Other	Spontaneous coronary artery dissection		Cardiovascular disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Angiopathy, hereditary, with nephropathy, aneurysms, and muscle cramps, MIM#611773				PMID: 35583931, 35234813, 37248441		False	3	100;0;0	0.56	True		ENSG00000187498	ENSG00000187498	HGNC:2202													
COL5A1	gene	COL5A1	Expert Review Green;Literature	Spontaneous coronary artery dissection		Cardiovascular disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	"Ehlers-Danlos syndrome, classic type, 1	MIM#130000;Fibromuscular dysplasia, multifocal	MIM#619329"				32938213		False	3	100;0;0	0.56	True		ENSG00000130635	ENSG00000130635	HGNC:2209													
FBN1	gene	FBN1	Expert Review Green;Literature	Spontaneous coronary artery dissection		Cardiovascular disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	"Marfan syndrome	MIM#154700;familial thoracic aortic aneurysm and aortic dissection MONDO:0019625, FBN1-related"				29357934		False	3	100;0;0	0.56	True		ENSG00000166147	ENSG00000166147	HGNC:3603													
SMAD2	gene	SMAD2	Expert Review Green;Literature	Spontaneous coronary artery dissection		Cardiovascular disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Loeys-Dietz syndrome 6, MIM# 619656				32897753;30448172		False	3	100;0;0	0.56	True		ENSG00000175387	ENSG00000175387	HGNC:6768													
SMAD3	gene	SMAD3	Expert Review Green;Literature	Spontaneous coronary artery dissection		Cardiovascular disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Loeys-Dietz syndrome 3, MIM# 613795				21217753;30661052;30071989		False	3	100;0;0	0.56	True		ENSG00000166949	ENSG00000166949	HGNC:6769													
TGFB2	gene	TGFB2	Expert Review Green;Literature	Spontaneous coronary artery dissection		Cardiovascular disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	"Loeys-Dietz syndrome 4	MIM#614816"				33125268;36103205		False	3	100;0;0	0.56	True		ENSG00000092969	ENSG00000092969	HGNC:11768													
TGFB3	gene	TGFB3	Expert Review Green;Literature	Spontaneous coronary artery dissection		Cardiovascular disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Loeys-Dietz syndrome 5 MIM#615582				32897753		False	3	100;0;0	0.56	True		ENSG00000119699	ENSG00000119699	HGNC:11769													
TGFBR2	gene	TGFBR2	Expert Review Green;Literature	Spontaneous coronary artery dissection		Cardiovascular disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	"Loeys-Dietz syndrome 2	MIM#610168"				32897753;35092149;36103205		False	3	100;0;0	0.56	True		ENSG00000163513	ENSG00000163513	HGNC:11773