Entity Name	Entity type	Gene Symbol	Sources(; separated)	Level4	Level3	Level2	Model_Of_Inheritance	Phenotypes	Omim	Orphanet	HPO	Publications	Description	Flagged	GEL_Status	UserRatings_Green_amber_red	version	ready	Mode of pathogenicity	EnsemblId(GRch37)	EnsemblId(GRch38)	HGNC	Position Chromosome	Position GRCh37 Start	Position GRCh37 End	Position GRCh38 Start	Position GRCh38 End	STR Repeated Sequence	STR Normal Repeats	STR Pathogenic Repeats	Region Haploinsufficiency Score	Region Triplosensitivity Score	Region Required Overlap Percentage	Region Variant Type	Region Verbose Name
ATP1A2	gene	ATP1A2	Expert Review Green;Victorian Clinical Genetics Services	Alternating Hemiplegia and Hemiplegic Migraine		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Alternating hemiplegia of childhood 1, MIM# 104290				24097848;21352219;17435187;15286158		False	3	100;0;0	0.57	True		ENSG00000018625	ENSG00000018625	HGNC:800													
ATP1A3	gene	ATP1A3	Expert Review Green;Victorian Clinical Genetics Services	Alternating Hemiplegia and Hemiplegic Migraine		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Alternating hemiplegia of childhood 2, MIM# 614820				22842232;22850527;24842602		False	3	100;0;0	0.57	True		ENSG00000105409	ENSG00000105409	HGNC:801													
CACNA1A	gene	CACNA1A	Expert Review Green;Victorian Clinical Genetics Services	Alternating Hemiplegia and Hemiplegic Migraine		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Migraine, familial hemiplegic, 1, MIM# 141500						False	3	100;0;0	0.57	True		ENSG00000141837	ENSG00000141837	HGNC:1388													
CST3	gene	CST3	Expert Review Green;Literature	Alternating Hemiplegia and Hemiplegic Migraine		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	leukodystrophy MONDO:0019046, CST3-related				38489591		False	3	100;0;0	0.57	True	Other	ENSG00000101439	ENSG00000101439	HGNC:2475													
KCNK18	gene	KCNK18	Expert Review Green;Victorian Clinical Genetics Services	Alternating Hemiplegia and Hemiplegic Migraine		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	{Migraine, with or without aura, susceptibility to, 13}, MIM# 613656				20871611;32394190;30573346;23904616;22355750		False	3	100;0;0	0.57	True		ENSG00000186795	ENSG00000186795	HGNC:19439													
PRRT2	gene	PRRT2	Expert Review Green;Victorian Clinical Genetics Services	Alternating Hemiplegia and Hemiplegic Migraine		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Convulsions, familial infantile, with paroxysmal choreoathetosis, 602066;Episodic kinesigenic dyskinesia 1, 128200;Seizures, benign familial infantile, 2, 605751				22101681;22744660;31124310;26561923;24928127		False	3	67;33;0	0.57	True		ENSG00000167371	ENSG00000167371	HGNC:30500													
RHOBTB2	gene	RHOBTB2	Expert Review Green;Literature	Alternating Hemiplegia and Hemiplegic Migraine		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	"Developmental and epileptic encephalopathy 64	618004;Alternating hemiplegia"				33504645		False	3	100;0;0	0.57	True		ENSG00000008853	ENSG00000008853	HGNC:18756													
SCN1A	gene	SCN1A	Expert Review Green;Victorian Clinical Genetics Services	Alternating Hemiplegia and Hemiplegic Migraine		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Migraine, familial hemiplegic, 3, MIM# 609634				31904117;30498473;30038559;29986598		False	3	100;0;0	0.57	True		ENSG00000144285	ENSG00000144285	HGNC:10585													
SCN2A	gene	SCN2A	Expert Review Green;Literature	Alternating Hemiplegia and Hemiplegic Migraine		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Alternating hemiplegia of childhood MONDO:0016241, SCN2A-related				38097767		False	3	100;0;0	0.57	True		ENSG00000136531	ENSG00000136531	HGNC:10588													
SLC1A3	gene	SLC1A3	Expert Review Green;Victorian Clinical Genetics Services	Alternating Hemiplegia and Hemiplegic Migraine		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Hemiplegic migraine				32754645;16116111		False	3	50;50;0	0.57	True		ENSG00000079215	ENSG00000079215	HGNC:10941													
SLC2A1	gene	SLC2A1	Expert Review Green;Victorian Clinical Genetics Services	Alternating Hemiplegia and Hemiplegic Migraine		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Hemiplegic migraine				25440161;24824604;20621801		False	3	100;0;0	0.57	True		ENSG00000117394	ENSG00000117394	HGNC:11005													
SLC4A4	gene	SLC4A4	Expert Review Green;Literature	Alternating Hemiplegia and Hemiplegic Migraine		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Renal tubular acidosis, proximal, with ocular abnormalities MIM#604278;hemiplegic migraine				20798035;33439394		False	3	100;0;0	0.57	True		ENSG00000080493	ENSG00000080493	HGNC:11030													
CACNB4	gene	CACNB4	Expert Review Amber;Victorian Clinical Genetics Services	Alternating Hemiplegia and Hemiplegic Migraine		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Episodic ataxia, type 5, MIM#613855				10762541;9628818;27003325		False	2	0;100;0	0.57	True		ENSG00000182389	ENSG00000182389	HGNC:1404													
CLDN5	gene	CLDN5	Expert Review Amber;Literature	Alternating Hemiplegia and Hemiplegic Migraine		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	alternating hemiplegia, MONDO:0016210, CLDN5-related				PMID: 35714222		False	2	0;100;0	0.57	True	Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments	ENSG00000184113	ENSG00000184113	HGNC:2047													
KCNA1	gene	KCNA1	Expert Review Amber;Victorian Clinical Genetics Services	Alternating Hemiplegia and Hemiplegic Migraine		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Episodic ataxia/myokymia syndrome, MIM# 160120				25642194		False	2	0;100;0	0.57	True		ENSG00000111262	ENSG00000111262	HGNC:6218													
NOTCH3	gene	NOTCH3	Expert list;Expert Review Amber	Alternating Hemiplegia and Hemiplegic Migraine		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Cerebral arteriopathy with subcortical infarcts and leukoencephalopathy 1 MIM#125310				22250206;10356105;27881154;28271496		False	2	0;100;0	0.57	True		ENSG00000074181	ENSG00000074181	HGNC:7883