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Gene: NGF

NGF (nerve growth factor)
EnsemblGeneIds (GRCh38): ENSG00000134259
EnsemblGeneIds (GRCh37): ENSG00000134259
OMIM: 162030, Gene2Phenotype
NGF is in 7 panels

1 review

Lauren Rogers (Victorian Clinical Genetics Services)

Green List (high evidence)

At least 10 families reported.

Onset in infancy.

Characterised by pain and temperature insensitivity and partial anhidrosis. Accidental injury and ulceration of the lips and tongue due to decreased sensation.
Created: 3 Oct 2024, 5:50 a.m. | Last Modified: 3 Oct 2024, 5:50 a.m.

Panel Version: 1.359

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Phenotypes
Neuropathy, hereditary sensory and autonomic, type V (MIM#608654)

Publications

Created: 3 Oct 2024, 5:50 a.m.
Last Modified: 3 Oct 2024, 5:50 a.m.
Panel version: 1.359

Details

Mode of Inheritance

BIALLELIC, autosomal or pseudoautosomal

Sources

Expert Review Green
Mackenzie's Mission

Phenotypes

Neuropathy, hereditary sensory and autonomic, type V, 608654 (3)

OMIM

162030

Clinvar variants

Variants in NGF

Penetrance

None

Publications

Panels with this gene

History Filter Activity

5 Oct 2024, Gel status: 3

Entity classified by Genomics England curator

Lilian Downie (Victorian Clinical Genetics Services)

Gene: ngf has been classified as Green List (High Evidence).

5 Oct 2024, Gel status: 3

Set publications

Lilian Downie (Victorian Clinical Genetics Services)

Publications for gene: NGF were set to

1 Jun 2022, Gel status: 3

Created, Added New Source, Set mode of inheritance, Set Phenotypes

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

gene: NGF was added gene: NGF was added to Reproductive Carrier Screen_VCGS. Sources: Mackenzie's Mission,Expert Review Green Mode of inheritance for gene: NGF was set to BIALLELIC, autosomal or pseudoautosomal Phenotypes for gene: NGF were set to Neuropathy, hereditary sensory and autonomic, type V, 608654 (3)

Prepair 1000+ Gene: NGF