Entity Name	Entity type	Gene Symbol	Sources(; separated)	Level4	Level3	Level2	Model_Of_Inheritance	Phenotypes	Omim	Orphanet	HPO	Publications	Description	Flagged	GEL_Status	UserRatings_Green_amber_red	version	ready	Mode of pathogenicity	EnsemblId(GRch37)	EnsemblId(GRch38)	HGNC	Position Chromosome	Position GRCh37 Start	Position GRCh37 End	Position GRCh38 Start	Position GRCh38 End	STR Repeated Sequence	STR Normal Repeats	STR Pathogenic Repeats	Region Haploinsufficiency Score	Region Triplosensitivity Score	Region Required Overlap Percentage	Region Variant Type	Region Verbose Name
ACBD6	gene	ACBD6	Expert Review Amber;Literature	Severe early-onset obesity		Endocrine disorders	BIALLELIC, autosomal or pseudoautosomal	Neurodevelopmental disorder with progressive movement abnormalities, MIM# 620785			Obesity;HP:0001513	36457943;21937992;35446914		False	2	0;100;0	1.13	True		ENSG00000230124	ENSG00000230124	HGNC:23339													
ADCY3	gene	ADCY3	Expert Review;Expert Review Amber	Severe early-onset obesity		Endocrine disorders	BIALLELIC, autosomal or pseudoautosomal	{Obesity, susceptibility to, BMIQ19} MIM#617885			Obesity;HP:0001513	11055432;29311636;29311637		False	2	50;50;0	1.13	True		ENSG00000138031	ENSG00000138031	HGNC:234													
BBIP1	gene	BBIP1	Expert list;Expert Review Amber	Severe early-onset obesity		Endocrine disorders	BIALLELIC, autosomal or pseudoautosomal	Bardet-Biedl syndrome 18, MIM#615995			Obesity;HP:0001513	24026985		False	2	0;100;0	1.13	True		ENSG00000214413	ENSG00000214413	HGNC:28093													
C8orf37	gene	C8orf37	Expert list;Expert Review Amber	Severe early-onset obesity		Endocrine disorders	BIALLELIC, autosomal or pseudoautosomal	Bardet-Biedl syndrome 21, MIM#617406			Obesity;HP:0001513	27008867;26854863		False	2	0;100;0	1.13	True		ENSG00000156172	ENSG00000156172	HGNC:27232													
CEP19	gene	CEP19	Expert list;Expert Review Amber;Genomics England PanelApp	Severe early-onset obesity		Endocrine disorders	BIALLELIC, autosomal or pseudoautosomal	Morbid obesity and spermatogenic failure, OMIM:615703;Bardet Biedl syndrome			Obesity;HP:0001513	24268657;29127258		False	2	0;50;50	1.13	True		ENSG00000174007	ENSG00000174007	HGNC:28209													
INPP5E	gene	INPP5E	Expert Review Amber;Genomics England PanelApp	Severe early-onset obesity		Endocrine disorders	BIALLELIC, autosomal or pseudoautosomal	Mental retardation, truncal obesity, retinal dystrophy, and micropenis, OMIM:610156			Obesity;HP:0001513	31173343;19668215		False	2	50;50;0	1.13	True		ENSG00000148384	ENSG00000148384	HGNC:21474													
MRAP2	gene	MRAP2	Expert Review Amber;Genomics England PanelApp	Severe early-onset obesity		Endocrine disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Susceptibility to obesity, MIM#615457			Obesity;HP:0001513	23869016;31700171;27474872;26795956		False	2	0;50;50	1.13	True		ENSG00000135324	ENSG00000135324	HGNC:21232													
TUB	gene	TUB	Expert Review Amber;Genomics England PanelApp	Severe early-onset obesity		Endocrine disorders	BIALLELIC, autosomal or pseudoautosomal	Retinal dystrophy and obesity, MIM# 616188			Obesity;HP:0001513	16443771;22618246;24375934;18619628;12076089;16643894;8612280;10629044;19885003;10196693;22492381;17955208 (candidate for late-onset obesity);18183286		False	2	0;50;50	1.13	True		ENSG00000166402	ENSG00000166402	HGNC:12406