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Fetal anomalies

Gene: TRAIP

Green List (high evidence)

TRAIP (TRAF interacting protein)
EnsemblGeneIds (GRCh38): ENSG00000183763
EnsemblGeneIds (GRCh37): ENSG00000183763
OMIM: 605958, Gene2Phenotype
TRAIP is in 6 panels

1 review

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Green List (high evidence)

Three families reported, though two distantly related (founder); functional data.
Created: 2 Apr 2021, 4:39 a.m. | Last Modified: 2 Apr 2021, 4:39 a.m.
Panel Version: 0.3588
Sources: Expert list
Created: 1 Mar 2020, 9:01 a.m.

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Phenotypes
Seckel syndrome 9, MIM#616777

Publications

Variants in this GENE are reported as part of current diagnostic practice

Details

Mode of Inheritance
BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Genomics England PanelApp
  • Expert list
Phenotypes
  • Seckel syndrome 9, MIM#616777
OMIM
605958
Clinvar variants
Variants in TRAIP
Penetrance
None
Publications
Panels with this gene

History Filter Activity

18 Jan 2022, Gel status: 3

Entity classified by Genomics England curator

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Gene: traip has been classified as Green List (High Evidence).

18 Jan 2022, Gel status: 3

Set Phenotypes

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Phenotypes for gene: TRAIP were changed from Seckel syndrome 9 to Seckel syndrome 9, MIM#616777

18 Jan 2022, Gel status: 3

Entity classified by Genomics England curator

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Gene: traip has been classified as Green List (High Evidence).

24 Oct 2021, Gel status: 2

Created, Added New Source, Set mode of inheritance, Set publications, Set Phenotypes

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

gene: TRAIP was added gene: TRAIP was added to Fetal anomalies. Sources: Expert Review Amber,Genomics England PanelApp Mode of inheritance for gene: TRAIP was set to BIALLELIC, autosomal or pseudoautosomal Publications for gene: TRAIP were set to 26595769 Phenotypes for gene: TRAIP were set to Seckel syndrome 9