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Mirror movements

Gene: DCC

Green List (high evidence)

DCC (DCC netrin 1 receptor)
EnsemblGeneIds (GRCh38): ENSG00000187323
EnsemblGeneIds (GRCh37): ENSG00000187323
OMIM: 120470, Gene2Phenotype
DCC is in 6 panels

1 review

Bryony Thompson (Royal Melbourne Hospital)

Green List (high evidence)

Well-established and most common cause of congenital mirror movements. >20 cases reported.
Sources: Expert list
Created: 1 Sep 2021, 10:56 p.m.

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Phenotypes
Mirror movements 1 and/or agenesis of the corpus callosum MIM#157600

Publications

Variants in this GENE are reported as part of current diagnostic practice

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • Expert list
Phenotypes
  • Mirror movements 1 and/or agenesis of the corpus callosum MIM#157600
OMIM
120470
Clinvar variants
Variants in DCC
Penetrance
None
Publications
Panels with this gene

History Filter Activity

1 Sep 2021, Gel status: 3

Entity classified by Genomics England curator

Bryony Thompson (Royal Melbourne Hospital)

Gene: dcc has been classified as Green List (High Evidence).

1 Sep 2021, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set publications, Set Phenotypes

Bryony Thompson (Royal Melbourne Hospital)

gene: DCC was added gene: DCC was added to Mirror movements. Sources: Expert list Mode of inheritance for gene: DCC was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Publications for gene: DCC were set to 20431009; 25763452; 28250454 Phenotypes for gene: DCC were set to Mirror movements 1 and/or agenesis of the corpus callosum MIM#157600 Review for gene: DCC was set to GREEN gene: DCC was marked as current diagnostic