Entity Name	Entity type	Gene Symbol	Sources(; separated)	Level4	Level3	Level2	Model_Of_Inheritance	Phenotypes	Omim	Orphanet	HPO	Publications	Description	Flagged	GEL_Status	UserRatings_Green_amber_red	version	ready	Mode of pathogenicity	EnsemblId(GRch37)	EnsemblId(GRch38)	HGNC	Position Chromosome	Position GRCh37 Start	Position GRCh37 End	Position GRCh38 Start	Position GRCh38 End	STR Repeated Sequence	STR Normal Repeats	STR Pathogenic Repeats	Region Haploinsufficiency Score	Region Triplosensitivity Score	Region Required Overlap Percentage	Region Variant Type	Region Verbose Name
ACBD6	gene	ACBD6	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Neurodevelopmental disorder with progressive movement abnormalities, MIM# 620785				37951597		False	3	100;0;0	3.65	True		ENSG00000230124	ENSG00000230124	HGNC:23339													
ACTB	gene	ACTB	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Baraitser-Winter syndrome 1, 243310;Dystonia, juvenile-onset, 607371				29788902;28487785		False	3	100;0;0	3.65	True	Other	ENSG00000075624	ENSG00000075624	HGNC:132													
ADAR	gene	ADAR	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Aicardi-Goutieres syndrome 6;neuroinflammatory disorder with cerebral calcification;progressive loss of cognition;spasticity;dystonia;parkinsonism;OMIM 615010				PMID: 32911246		False	3	100;0;0	3.65	True		ENSG00000160710	ENSG00000160710	HGNC:225													
ADAR	gene	ADAR	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	dystonia;Aicardi-Goutieres syndrome 6, 615010						False	3	100;0;0	3.65	False		ENSG00000160710	ENSG00000160710	HGNC:225													
ADCY5	gene	ADCY5	Expert Review Green;Royal Children's Hospital Neurology Department;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Dyskinesia, familial, with facial myokymia, MIM# 606703;MONDO:0011707;Hyperkinetic movement disorder with dyskinesia, myoclonus, chorea, and dystonia-2 (HYDMCD2), MIM#619647;Neurodevelopmental disorder with hyperkinetic movements and dyskinesia (NEDHYD), MIM#619651				22782511;24700542;33051786;32647899;33704598;34631954;28971144;30975617		False	3	100;0;0	3.65	True		ENSG00000173175	ENSG00000173175	HGNC:236													
ADCY5	gene	ADCY5	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Dyskinesia, familial, with facial myokymia, MIM# 606703;MONDO:0011707;Hyperkinetic movement disorder with dyskinesia, myoclonus, chorea, and dystonia-2 (HYDMCD2), MIM#619647;Neurodevelopmental disorder with hyperkinetic movements and dyskinesia (NEDHYD), MIM#619651				22782511;24700542;33051786;32647899;33704598;34631954;28971144;30975617		False	3	100;0;0	3.65	True		ENSG00000173175	ENSG00000173175	HGNC:236													
ALDH5A1	gene	ALDH5A1	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Succinic semialdehyde dehydrogenase deficiency, MIM# 271980				17438226;38499966		False	3	100;0;0	3.65	True		ENSG00000112294	ENSG00000112294	HGNC:408													
ANO3	gene	ANO3	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Dystonia 24, 615034;familial form of cranio-cervical dystonia				33388357		False	3	100;0;0	3.65	True		ENSG00000134343	ENSG00000134343	HGNC:14004													
APTX	gene	APTX	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Ataxia-oculomotor apraxia type 1;Dystonia				15876520		False	3	100;0;0	3.65	True		ENSG00000137074	ENSG00000137074	HGNC:15984													
ARFGEF3	gene	ARFGEF3	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Dystonia, MONDO:0044807, ARFGEF3-related				PMID: 33098801		False	3	100;0;0	3.65	True		ENSG00000112379	ENSG00000112379	HGNC:21213													
ARSA	gene	ARSA	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Metachromatic leukodystrophy, MIM#250100						False	3	100;0;0	3.65	True		ENSG00000100299	ENSG00000100299	HGNC:713													
ARX	gene	ARX	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)	Partington syndrome, MIM# 309510;Dystonia				11889467;15200506		False	3	100;0;0	3.65	True	Other	ENSG00000004848	ENSG00000004848	HGNC:18060													
ATAD1	gene	ATAD1	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Hyperekplexia 4, MIM#618011				28180185;29390050;29659736		False	3	100;0;0	3.65	True		ENSG00000138138	ENSG00000138138	HGNC:25903													
ATM	gene	ATM	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Ataxia telangiectasia;Dystonia						False	3	100;0;0	3.65	False		ENSG00000149311	ENSG00000149311	HGNC:795													
ATP13A2	gene	ATP13A2	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Kufor-Rakeb syndrome MIM#606693				21094623;20853184;20310007		False	3	100;0;0	3.65	True		ENSG00000159363	ENSG00000159363	HGNC:30213													
ATP13A2	gene	ATP13A2	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	parkinsonism due to ATP13A2 deficiency MONDO:0017809				25900096;20301402		False	3	100;0;0	3.65	True		ENSG00000159363	ENSG00000159363	HGNC:30213													
ATP1A2	gene	ATP1A2	Royal Children's Hospital Neurology Department;Expert Review Green;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	Unknown							False	3	0;0;0	3.65	False		ENSG00000018625	ENSG00000018625	HGNC:800													
ATP1A3	gene	ATP1A3	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	ATP1A3-associated neurological disorder MONDO:0700002				20301294;17282997;15260953;17595045;17516473;22534615		False	3	100;0;0	3.65	True		ENSG00000105409	ENSG00000105409	HGNC:801													
ATP1A3	gene	ATP1A3	Royal Children's Hospital Neurology Department;Expert Review Green;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	Unknown							False	3	0;0;0	3.65	False		ENSG00000105409	ENSG00000105409	HGNC:801													
ATP1A3	gene	ATP1A3	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Dystonia-12, MIM# 128235;Rapid dystonia-parkinsonism MONDO:0007496				15260953;17282997;19351654		False	3	100;0;0	3.65	True		ENSG00000105409	ENSG00000105409	HGNC:801													
ATP2B2	gene	ATP2B2	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Neurodevelopmental Disorder, MONDO:0700092, ATP2B2-related				PMID: 37675773		False	3	100;0;0	3.65	True	Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments	ENSG00000157087	ENSG00000157087	HGNC:815													
ATP5G3	gene	ATP5G3	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	"Dystonia, early-onset, and/or spastic paraplegia, MIM#	619681"				34636445;34954817		False	3	100;0;0	3.65	True		ENSG00000154518	ENSG00000154518	HGNC:843													
ATP6AP2	gene	ATP6AP2	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	X-LINKED: hemizygous mutation in males, biallelic mutations in females	"Parkinsonism with spasticity, X-linked, MIM#	300911"				30985297;23595882		False	3	100;0;0	3.65	True		ENSG00000182220	ENSG00000182220	HGNC:18305													
ATP7B	gene	ATP7B	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Wilson disease, MIM# 277900;Dystonia				32662046		False	3	100;0;0	3.65	True		ENSG00000123191	ENSG00000123191	HGNC:870													
ATP7B	gene	ATP7B	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Wilson disease MIM#277900				17435591		False	3	50;50;0	3.65	True		ENSG00000123191	ENSG00000123191	HGNC:870													
AUH	gene	AUH	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	3-Methylglutaconic aciduria type 1;Dystonia						False	3	100;0;0	3.65	True		ENSG00000148090	ENSG00000148090	HGNC:890													
BCAP31	gene	BCAP31	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	X-LINKED: hemizygous mutation in males, biallelic mutations in females	Deafness, dystonia and cerebellar hypomyelination, MIM#300475				24011989;28332767;30713915;31330203;32652807		False	3	100;0;0	3.65	True		ENSG00000185825	ENSG00000185825	HGNC:16695													
C19orf12	gene	C19orf12	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	neurodegeneration with brain iron accumulation 4 MONDO:0013674				21981780;23278385;23447832		False	3	100;0;0	3.65	True		ENSG00000131943	ENSG00000131943	HGNC:25443													
C19orf12	gene	C19orf12	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	neurodegeneration with brain iron accumulation 4 MONDO:0013674				21981780;22508347		False	3	100;0;0	3.65	True		ENSG00000131943	ENSG00000131943	HGNC:25443													
C9orf3	gene	C9orf3	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	"Dystonia 31, MIM#	619565"				34596301		False	3	100;0;0	3.65	True		ENSG00000148120	ENSG00000148120	HGNC:1361													
C9orf3	gene	C9orf3	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Dystonia 31, MIM# 619565;Childhood/Adolescence onset generalised dystonia;Dystonia parkinsonism;Zech-Boesch Syndrome				PMID: 35306330		False	3	100;0;0	3.65	True		ENSG00000148120	ENSG00000148120	HGNC:1361													
CACNA1A	gene	CACNA1A	Royal Children's Hospital Neurology Department;Expert Review Green;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	Unknown							False	3	0;0;0	3.65	False		ENSG00000141837	ENSG00000141837	HGNC:1388													
CACNA1A	gene	CACNA1A	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Episodic ataxia, type 2 MIM#108500;Spinocerebellar ataxia 6 MIM#183086				25468264;23441182;19232643;18758887;11344116		False	3	100;0;0	3.65	True		ENSG00000141837	ENSG00000141837	HGNC:1388													
CACNA1G	gene	CACNA1G	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	"Spinocerebellar ataxia 42, early-onset, severe, with neurodevelopmental deficits, MIM#	618087"				29878067		False	3	100;0;0	3.65	True		ENSG00000006283	ENSG00000006283	HGNC:1394													
CACNA1S	gene	CACNA1S	Expert Review Green;Royal Children's Hospital Neurology Department;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Hypokalemic periodic paralysis, type 1, MIM# 170400				11591859		False	3	100;0;0	3.65	True		ENSG00000081248	ENSG00000081248	HGNC:1397													
CAMK4	gene	CAMK4	Expert Review Green;Expert Review	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Intellectual disability;Autism;Behavioral abnormality;Abnormality of movement;Dystonia;Ataxia;Chorea;Myoclonus				30262571;33098801;33211350		False	3	100;0;0	3.65	True		ENSG00000152495	ENSG00000152495	HGNC:1464													
CASR	gene	CASR	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	"Hypocalciuric hypercalcemia, type I, MIM#	145980;Hypocalciuric Hypercalcemic;Hyperparathyroidism;paroxysmal dyskinesia;brain calcification"				34913197		False	3	100;0;0	3.65	True		ENSG00000036828	ENSG00000036828	HGNC:1514													
CHCHD2	gene	CHCHD2	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Parkinson disease 22, autosomal dominant MIM#616710				32068847;25662902;31600778;26705026		False	3	100;0;0	3.65	False		ENSG00000106153	ENSG00000106153	HGNC:21645													
CLCN1	gene	CLCN1	Expert Review Green;Expert Review	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	"Myotonia congenita, dominant, MIM#	160800;Myotonia congenita, recessive, MIM#	255700"						False	3	100;0;0	3.65	True		ENSG00000188037	ENSG00000188037	HGNC:2019													
CLDN5	gene	CLDN5	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Syndromic disorder, MONDO:0002254, CLDN5-related;familial migraine;alternating hemiplegia;hemiplegic migraine;brain calcification;acquired microcephaly;epilepsy				35714222;36825455		False	3	100;0;0	3.65	True		ENSG00000184113	ENSG00000184113	HGNC:2047													
CLN3	gene	CLN3	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	"Ceroid lipofuscinosis, neuronal, 3	204200"				19353721		False	3	100;0;0	3.65	True		ENSG00000188603	ENSG00000188603	HGNC:2074													
CLN3	gene	CLN3	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Ceroid lipofuscinosis, neuronal, 3 MIM#204200				19489875;11342698		False	3	100;0;0	3.65	True		ENSG00000188603	ENSG00000188603	HGNC:2074													
COASY	gene	COASY	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	neurodegeneration with brain iron accumulation 6, MONDO:0014290;Neurodegeneration with brain iron accumulation 6 615643				23447832;24360804;27021474		False	3	100;0;0	3.65	True		ENSG00000068120	ENSG00000068120	HGNC:29932													
COQ8A	gene	COQ8A	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	"Coenzyme Q10 deficiency, primary, 4, MIM#	612016"				32337771		False	3	100;0;0	3.65	True		ENSG00000163050	ENSG00000163050	HGNC:16812													
CP	gene	CP	Expert Review Green;Royal Melbourne Hospital;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Aceruloplasminaemia, MIM#604290						False	3	100;0;0	3.65	True		ENSG00000047457	ENSG00000047457	HGNC:2295													
CP	gene	CP	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Aceruloplasminaemia, MIM#604290						False	3	100;0;0	3.65	True		ENSG00000047457	ENSG00000047457	HGNC:2295													
CSF1R	gene	CSF1R	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	leukoencephalopathy, diffuse hereditary, with spheroids 1 MONDO:0800027				25935893;22934315;22934315		False	3	100;0;0	3.65	True		ENSG00000182578	ENSG00000182578	HGNC:2433													
CYP27A1	gene	CYP27A1	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	"Cerebrotendinous xanthomatosis, MIM#	213700;Cerebrotendinous xanthomatosis,  infantile-onset diarrhoea, juvenile-onset cataract, young adult-onset tendon xanthomas;Epilepsy;Parkinsonism;Ataxia;Peripheral neuropathy"				PMID: 30054180		False	3	100;0;0	3.65	True		ENSG00000135929	ENSG00000135929	HGNC:2605													
CYP27A1	gene	CYP27A1	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Cerebrotendinous xanthomatosis, MIM# 213700;Cholestanol storage disease;Dystonia				19373932;21531161;25424010		False	3	100;0;0	3.65	True		ENSG00000135929	ENSG00000135929	HGNC:2605													
DCAF17	gene	DCAF17	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Woodhouse-Sakati syndrome MONDO:0009419;Dystonia				18175354;36185913;17167799		False	3	100;0;0	3.65	True		ENSG00000115827	ENSG00000115827	HGNC:25784													
DCTN1	gene	DCTN1	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Perry syndrome MONDO:0008201				20945553		False	3	100;0;0	3.65	True		ENSG00000204843	ENSG00000204843	HGNC:2711													
DDC	gene	DDC	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Aromatic L-amino acid decarboxylase deficiency, 608643;Dystonia				20505134		False	3	100;0;0	3.65	True		ENSG00000132437	ENSG00000132437	HGNC:2719													
DLAT	gene	DLAT	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Pyruvate dehydrogenase E2 deficiency, MIM# 245348;Episodic dystonia (Exercise induced or without clear trigger)				20022530;29093066		False	3	100;0;0	3.65	True		ENSG00000150768	ENSG00000150768	HGNC:2896													
DLAT	gene	DLAT	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Pyruvate dehydrogenase E2 deficiency 245348;Dystonia				39007626;20022530;16049940		False	3	100;0;0	3.65	True		ENSG00000150768	ENSG00000150768	HGNC:2896													
DNAJC12	gene	DNAJC12	Expert Review Green;Royal Melbourne Hospital;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Hyperphenylalaninemia, mild, non-BH4-deficient, 617384						False	3	100;0;0	3.65	True		ENSG00000108176	ENSG00000108176	HGNC:28908													
DNAJC12	gene	DNAJC12	Expert Review Green;Expert Review	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Hyperphenylalaninemia, mild, non-BH4-deficient, MIM#617384						False	3	100;0;0	3.65	True		ENSG00000108176	ENSG00000108176	HGNC:28908													
DNAJC5	gene	DNAJC5	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Ceroid lipofuscinosis, neuronal, 4, Parry type, MIM# 162350				22978711;21820099;22235333		False	3	100;0;0	3.65	True		ENSG00000101152	ENSG00000101152	HGNC:16235													
DNAJC6	gene	DNAJC6	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	juvenile onset Parkinson disease 19A MONDO:0014231				33983693		False	3	100;0;0	3.65	True		ENSG00000116675	ENSG00000116675	HGNC:15469													
ECHS1	gene	ECHS1	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Mitochondrial short-chain enoyl-CoA hydratase 1 deficiency 616277;Dystonia				32858208		False	3	100;0;0	3.65	True		ENSG00000127884	ENSG00000127884	HGNC:3151													
ECHS1	gene	ECHS1	Expert Review Green;Expert Review	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	"Mitochondrial short-chain enoyl-CoA hydratase 1 deficiency, MIM#	616277"				32677093;32858208		False	3	100;0;0	3.65	True		ENSG00000127884	ENSG00000127884	HGNC:3151													
ECHS1	gene	ECHS1	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Mitochondrial short-chain enoyl-CoA hydratase 1 deficiency, MIM# 616277;paroxysmal dyskinesia (isolated or with other features of a mitochondrial disease)				27090768;28039521		False	3	100;0;0	3.65	True		ENSG00000127884	ENSG00000127884	HGNC:3151													
EIF2AK2	gene	EIF2AK2	Expert Review Green;Expert Review	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Intellectual disability;white matter abnormalities;ataxia;regression with febrile illness;early onset dystonia				33236446;33866603		False	3	100;0;0	3.65	True		ENSG00000055332	ENSG00000055332	HGNC:9437													
EIF2AK2	gene	EIF2AK2	Expert Review Green;Expert Review	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Dystonia 33, MIM# 619687				PMID: 35146068;PMID: 33236446;PMID: 33866603		False	3	100;0;0	3.65	True		ENSG00000055332	ENSG00000055332	HGNC:9437													
EIF2AK2	gene	EIF2AK2	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Leukoencephalopathy, developmental delay, and episodic neurologic regression syndrome, MIM# 618877;Neurodevelopmental Syndrome;Developmental delays;Ataxia;Parkinsonism;White matter alterations				PMID: 32197074		False	3	100;0;0	3.65	True		ENSG00000055332	ENSG00000055332	HGNC:9437													
EIF4A2	gene	EIF4A2	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Neurodevelopmental disorder with hypotonia and speech delay, with or without seizures, MIM# 620455				37485550		False	3	100;0;0	3.65	True		ENSG00000156976	ENSG00000156976	HGNC:3284													
FA2H	gene	FA2H	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Dystonia;Spastic paraplegia 35, autosomal recessive 612319;fatty acid hydroxylase-associated neurodegeneration				19068277;20104589;20853438;31135052		False	3	100;0;0	3.65	True		ENSG00000103089	ENSG00000103089	HGNC:21197													
FBXO28	gene	FBXO28	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Developmental and epileptic encephalopathy 100, MIM# 619777				33280099		False	3	100;0;0	3.65	True		ENSG00000143756	ENSG00000143756	HGNC:29046													
FBXO7	gene	FBXO7	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	parkinsonian-pyramidal syndrome MONDO:0009830				20301402		False	3	100;0;0	3.65	True		ENSG00000100225	ENSG00000100225	HGNC:13586													
FBXO7	gene	FBXO7	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	juvenile parkinsonism;Dystonia						False	3	0;0;0	3.65	False		ENSG00000100225	ENSG00000100225	HGNC:13586													
FITM2	gene	FITM2	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Siddiqi syndrome MIM#618635;dystonia;deafness				28067622;30214770;30288795		False	3	100;0;0	3.65	True		ENSG00000197296	ENSG00000197296	HGNC:16135													
FOXG1	gene	FOXG1	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Rett syndrome, congenital variant;Dystonia				27029630		False	3	100;0;0	3.65	True		ENSG00000176165	ENSG00000176165	HGNC:3811													
FOXG1	gene	FOXG1	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	"Rett syndrome, congenital variant, MIM#	613454;Developmental and Epileptic Encephalopathy;Dystonia,;Athetosis;Parkinsonism;Stereotypies"				PMID: 21953941		False	3	100;0;0	3.65	True		ENSG00000176165	ENSG00000176165	HGNC:3811													
FRRS1L	gene	FRRS1L	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Developmental and epileptic encephalopathy 37, MIM# 616981;Seizures;Chorea;Parkinsonism;Developmental delay				PMID: 29086067		False	3	100;0;0	3.65	True		ENSG00000260230	ENSG00000260230	HGNC:1362													
FTL	gene	FTL	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Neurodegeneration with brain iron accumulation 3, MIM# 606159				11438811;15099026;12746423;18413574		False	3	100;0;0	3.65	True		ENSG00000087086	ENSG00000087086	HGNC:3999													
FTL	gene	FTL	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted					23447832;20301320		False	3	100;0;0	3.65	False		ENSG00000087086	ENSG00000087086	HGNC:3999													
FUCA1	gene	FUCA1	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Fucosidosis, MIM#230000				31064022		False	3	100;0;0	3.65	True		ENSG00000179163	ENSG00000179163	HGNC:4006													
GABRB2	gene	GABRB2	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	epileptic encephalopathy, infantile or early childhood, 2 MONDO:0020631				38996765		False	3	100;0;0	3.65	True	Other	ENSG00000145864	ENSG00000145864	HGNC:4082													
GABRB3	gene	GABRB3	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Developmental and epileptic encephalopathy 43 MIM#617113				37647766		False	3	100;0;0	3.65	True	Other	ENSG00000166206	ENSG00000166206	HGNC:4083													
GABRB3	gene	GABRB3	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Developmental and epileptic encephalopathy 43 MIM#617113				37647766		False	3	100;0;0	3.65	True	Other	ENSG00000166206	ENSG00000166206	HGNC:4083													
GALT	gene	GALT	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	"Galactosemia,	MIM#230400"				30718057		False	3	100;0;0	3.65	True		ENSG00000213930	ENSG00000213930	HGNC:4135													
GAMT	gene	GAMT	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Cerebral creatine deficiency syndrome 2 MIM#612736				19027335;33996490;12557293;19288536;16855203		False	3	50;0;50	3.65	True		ENSG00000130005	ENSG00000130005	HGNC:4136													
GBA	gene	GBA	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	"Gaucher disease, type III, MIM#	231000"				27789132		False	3	100;0;0	3.65	True		ENSG00000177628	ENSG00000177628	HGNC:4177													
GBA	gene	GBA	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Parkinson's disease, MONDO:0005180, GBA-related				PMID: 12809640;35639160		False	3	100;0;0	3.65	True		ENSG00000177628	ENSG00000177628	HGNC:4177													
GCDH	gene	GCDH	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	glutaryl-CoA dehydrogenase deficiency MONDO:0009281				32777384;21912879;31536184		False	3	100;0;0	3.65	True		ENSG00000105607	ENSG00000105607	HGNC:4189													
GCH1	gene	GCH1	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	"Dopa-responsive dystonia;exercise-induced dystonia;Dystonia, DOPA-responsive, with or without hyperphenylalaninemia	128230"						False	3	100;0;0	3.65	True		ENSG00000131979	ENSG00000131979	HGNC:4193													
GCH1	gene	GCH1	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Dystonia, DOPA-responsive, with or without hyperphenylalaninemia, MIM# 128230				7874165;11113234;15753436		False	3	100;0;0	3.65	True		ENSG00000131979	ENSG00000131979	HGNC:4193													
GCH1	gene	GCH1	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Dystonia, DOPA-responsive, with or without hyperphenylalaninemia, MIM# 128230				32170445;32278297;32746945;30314816		False	3	100;0;0	3.65	True		ENSG00000131979	ENSG00000131979	HGNC:4193													
GJC2	gene	GJC2	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	"Leukodystrophy, hypomyelinating, 2, MIM#	608804"				15192806;18094336		False	3	100;0;0	3.65	True		ENSG00000198835	ENSG00000198835	HGNC:17494													
GLB1	gene	GLB1	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	GM1 gangliosidosis type 3 MONDO:0009262				24156116;35937492;34514040;1353343		False	3	100;0;0	3.65	True		ENSG00000170266	ENSG00000170266	HGNC:4298													
GLB1	gene	GLB1	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	GM1-gangliosidosis, type III , MIM#230650;Parkinsonism				PMID: 34514040		False	3	100;0;0	3.65	True		ENSG00000170266	ENSG00000170266	HGNC:4298													
GLRA1	gene	GLRA1	Expert Review Green;Royal Children's Hospital Neurology Department;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Hyperekplexia 1, MIM# 149400				8298642;16832093		False	3	100;0;0	3.65	True		ENSG00000145888	ENSG00000145888	HGNC:4326													
GLRB	gene	GLRB	Expert Review Green;Royal Children's Hospital Neurology Department;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Hyperekplexia 2, MIM# 614619				21391991;11929858;27843043		False	3	100;0;0	3.65	True		ENSG00000109738	ENSG00000109738	HGNC:4329													
GM2A	gene	GM2A	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	GM2-gangliosidosis, AB variant, MIM#272750						False	3	100;0;0	3.65	True		ENSG00000196743	ENSG00000196743	HGNC:4367													
GNAL	gene	GNAL	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Dystonia 25, MIM# 615073;MONDO:0014033				23222958;33175450;32180288		False	3	100;0;0	3.65	True		ENSG00000141404	ENSG00000141404	HGNC:4388													
GNAO1	gene	GNAO1	Expert Review Green;Royal Children's Hospital Neurology Department;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Epileptic encephalopathy, early infantile, 17;Neurodevelopmental disorder with involuntary movements				28747448;30682224		False	3	100;0;0	3.65	True	Other	ENSG00000087258	ENSG00000087258	HGNC:4389													
GNAO1	gene	GNAO1	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Neurodevelopmental disorder with involuntary movements, 617493				28747448;30682224		False	3	100;0;0	3.65	True	Other	ENSG00000087258	ENSG00000087258	HGNC:4389													
GNB1	gene	GNB1	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Mental retardation, autosomal dominant 42, MIM# 616973;Myoclonus dystonia				30194818;27108799;27668284;31034681		False	3	100;0;0	3.65	True		ENSG00000078369	ENSG00000078369	HGNC:4396													
GRIN1	gene	GRIN1	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Neurodevelopmental disorder with or without hyperkinetic movements and seizures, autosomal dominant, MIM# 614254;Neurodevelopmental disorder with or without hyperkinetic movements and seizures, autosomal recessive, MIM# 617820				29365063;27164704;27164704;28051072		False	3	100;0;0	3.65	True		ENSG00000176884	ENSG00000176884	HGNC:4584													
GRN	gene	GRN	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	"Frontotemporal lobar degeneration with ubiquitin-positive inclusions,	MIM#607485"						False	3	100;0;0	3.65	True		ENSG00000030582	ENSG00000030582	HGNC:4601													
GRN	gene	GRN	Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services;Expert Review Green	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Frontotemporal lobar degeneration with ubiquitin-positive inclusions, MIM# 607485				17923627;20301545		False	3	100;0;0	3.65	False		ENSG00000030582	ENSG00000030582	HGNC:4601													
GTPBP2	gene	GTPBP2	Expert Review Green;Expert Review	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Jaberi-Elahi syndrome, MIM#617988				26675814;29449720;30790272		False	3	100;0;0	3.65	True		ENSG00000172432	ENSG00000172432	HGNC:4670													
HIBCH	gene	HIBCH	Expert Review Green;Expert Review	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	"3-hydroxyisobutryl-CoA hydrolase deficiency, MIM#	250620"				26026795;25251209;24299452;32677093		False	3	100;0;0	3.65	True		ENSG00000198130	ENSG00000198130	HGNC:4908													
HIBCH	gene	HIBCH	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	3-hydroxyisobutryl-CoA hydrolase deficiency, MIM# 250620;Paroxysmal dyskinesia (exercise induced or without clear trigger;isolated or with additional features;mitochondrial disorder (Leigh syndrome);neurodevelopmental disability;epilepsy.				PMID 31679561		False	3	100;0;0	3.65	True		ENSG00000198130	ENSG00000198130	HGNC:4908													
HPCA	gene	HPCA	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Dystonia 2, torsion, autosomal recessive, 224500;MONDO:0009141;childhood-onset generalized dystonia;adolescence-onset segmental dystonia;generalized dystonia with additional neurological features				25799108;30991467;30145809		False	3	100;0;0	3.65	True		ENSG00000121905	ENSG00000121905	HGNC:5144													
HPRT1	gene	HPRT1	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	X-LINKED: hemizygous mutation in males, biallelic mutations in females	Lesch-Nyhan syndrome;Dystonia				20301328		False	3	100;0;0	3.65	True		ENSG00000165704	ENSG00000165704	HGNC:5157													
HTRA2	gene	HTRA2	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	3-methylglutaconic aciduria type 8 MONDO:0044723				27208207;27696117;30114719		False	3	50;50;0	3.65	True		ENSG00000115317	ENSG00000115317	HGNC:14348													
IMPDH2	gene	IMPDH2	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Neurodevelopmental disorder with dystonia				PMID: 33098801		False	3	100;0;0	3.65	True		ENSG00000178035	ENSG00000178035	HGNC:6053													
IRF2BPL	gene	IRF2BPL	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Neurodevelopmental disorder with regression, abnormal movements, loss of speech, and seizures 618088				PMID: 30057031;30166628		False	3	100;0;0	3.65	True		ENSG00000119669	ENSG00000119669	HGNC:14282													
KCNA1	gene	KCNA1	Royal Children's Hospital Neurology Department;Expert Review Green;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	Unknown							False	3	0;0;0	3.65	False		ENSG00000111262	ENSG00000111262	HGNC:6218													
KCNA2	gene	KCNA2	Expert Review Green;Royal Children's Hospital Neurology Department;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Episodic ataxia;Epileptic encephalopathy, early infantile, 32, MIM# 616366				27733563;27543892;25477152		False	3	100;0;0	3.65	True		ENSG00000177301	ENSG00000177301	HGNC:6220													
KCNJ10	gene	KCNJ10	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Paroxysmal dyskinesia, MONDO:0015427, KCNJ10-related				38979912;38436103		False	3	100;0;0	3.65	True		ENSG00000177807	ENSG00000177807	HGNC:6256													
KCNJ2	gene	KCNJ2	Royal Children's Hospital Neurology Department;Expert Review Green;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	Unknown							False	3	0;0;0	3.65	False		ENSG00000123700	ENSG00000123700	HGNC:6263													
KCNMA1	gene	KCNMA1	Expert Review Green;Royal Children's Hospital Neurology Department;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Paroxysmal nonkinesigenic dyskinesia, 3, with or without generalized epilepsy, MIM# 609446				15937479;26195193		False	3	100;0;0	3.65	True		ENSG00000156113	ENSG00000156113	HGNC:6284													
KCNMA1	gene	KCNMA1	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Paroxysmal nonkinesigenic dyskinesia, 3, with or without generalized epilepsy MIM#609446				26195193;15937479;29356177		False	3	100;0;0	3.65	True	Other	ENSG00000156113	ENSG00000156113	HGNC:6284													
KCNN2	gene	KCNN2	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Dystonia 34, myoclonic, MIM#619724;Neurodevelopmental disorder with or without variable movement or behavioural abnormalities, MIM#619725				32212350;33242881		False	3	100;0;0	3.65	True		ENSG00000080709	ENSG00000080709	HGNC:6291													
KCNQ2	gene	KCNQ2	Royal Children's Hospital Neurology Department;Expert Review Green;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	Unknown							False	3	0;0;0	3.65	False		ENSG00000075043	ENSG00000075043	HGNC:6296													
KCNQ3	gene	KCNQ3	Expert Review Green;Royal Children's Hospital Neurology Department;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Seizures, benign neonatal, 2, MIM# 121201				33337327;25524373;24851285		False	3	100;0;0	3.65	True		ENSG00000184156	ENSG00000184156	HGNC:6297													
KCTD17	gene	KCTD17	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Dystonia 26, myoclonic MIM#616398				25983243;30642807;30579817		False	3	100;0;0	3.65	True		ENSG00000100379	ENSG00000100379	HGNC:25705													
KIAA1161	gene	KIAA1161	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Basal ganglia calcification, idiopathic, 7, autosomal recessive, OMIM #618317;Primary familial brain calcification;Atypical parkinsonism;Supranuclear gaze palsy				32211515;30656188;30649222;30460687;29910000;31951047		False	3	100;0;0	3.65	True		ENSG00000164976	ENSG00000164976	HGNC:19918													
KIAA1161	gene	KIAA1161	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Basal ganglia calcification, idiopathic, 7, autosomal recessive, OMIM #618317;paroxysmal dyskinesia;brain calcification;episodic hemiparesis				34346093;34783389;32303062		False	3	100;0;0	3.65	True		ENSG00000164976	ENSG00000164976	HGNC:19918													
KIF1A	gene	KIF1A	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Dystonia;spastic paraplegia;intellectual disability				32096284;32935419		False	3	100;0;0	3.65	False		ENSG00000130294	ENSG00000130294	HGNC:888													
KMT2B	gene	KMT2B	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Dystonia 28, childhood-onset , MIM#617284				PMID: 33816656		False	3	100;0;0	3.65	True		ENSG00000272333	ENSG00000272333	HGNC:15840													
KMT2B	gene	KMT2B	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	early-onset dystonia;Dystonia 28, childhood-onset 617284;MONDO:0015004				27839873;27992417		False	3	100;0;0	3.65	True		ENSG00000272333	ENSG00000272333	HGNC:15840													
L2HGDH	gene	L2HGDH	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	L-2-hydroxyglutaric aciduria MIM#236792				24753671;18780161;15824270;10399870		False	3	100;0;0	3.65	True		ENSG00000087299	ENSG00000087299	HGNC:20499													
LRRK2	gene	LRRK2	Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services;Expert Review Green	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted							False	3	100;0;0	3.65	False		ENSG00000188906	ENSG00000188906	HGNC:18618													
LYST	gene	LYST	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Chediak-Higashi syndrome MONDO:0008963				23436631;23521865;20301751		False	3	100;0;0	3.65	True		ENSG00000143669	ENSG00000143669	HGNC:1968													
MAPT	gene	MAPT	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	late-onset Parkinson disease MONDO:0008199				20301678		False	3	100;0;0	3.65	True		ENSG00000186868	ENSG00000186868	HGNC:6893													
MARS2	gene	MARS2	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Spastic ataxia 3, autosomal recessive MIM#611390				16672289;22448145		False	3	100;0;0	3.65	True		ENSG00000247626	ENSG00000247626	HGNC:25133													
MECP2	gene	MECP2	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	X-LINKED: hemizygous mutation in males, biallelic mutations in females	MECP2-related disorders;Rett syndrome, MIM# 312750;Mental retardation, X-linked, syndromic 13, MIM# 300055				31970230;27050783		False	3	100;0;0	3.65	True		ENSG00000169057	ENSG00000169057	HGNC:6990													
MECR	gene	MECR	Expert Review Green;Expert Review	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Dystonia, childhood-onset, with optic atrophy and basal ganglia abnormalities, MIM# 617282;MONDO:0015003				27817865;33401012;31137067;31070877		False	3	100;0;0	3.65	True		ENSG00000116353	ENSG00000116353	HGNC:19691													
MECR	gene	MECR	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Dystonia, childhood-onset, with optic atrophy and basal ganglia abnormalities, MIM# 617282;MONDO:0015003				27817865;33401012;31137067;31070877		False	3	100;0;0	3.65	True		ENSG00000116353	ENSG00000116353	HGNC:19691													
MED27	gene	MED27	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Intellectual disability;cerebellar hypoplasia;dystonia				33443317		False	3	100;0;0	3.65	False		ENSG00000160563	ENSG00000160563	HGNC:2377													
NIT1	gene	NIT1	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Cerebrovascular disorder, NIT1-related (MONDO:0011057)				38430071		False	3	100;0;0	3.65	True		ENSG00000158793	ENSG00000158793	HGNC:7828													
NKX2-1	gene	NKX2-1	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Chorea, hereditary benign MIM#118700;Choreoathetosis, hypothyroidism, and neonatal respiratory distress MIM#610978				24714694;30186310		False	3	100;0;0	3.65	True		ENSG00000136352	ENSG00000136352	HGNC:11825													
NKX6-2	gene	NKX6-2	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Spastic ataxia 8, autosomal recessive, with hypomyelinating leukodystrophy MIM#617560				30285346;28575651;28969374		False	3	100;0;0	3.65	True		ENSG00000148826	ENSG00000148826	HGNC:19321													
NPC1	gene	NPC1	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Niemann-Pick disease, type C1 MONDO:0009757				12555942;20301473		False	3	100;0;0	3.65	True		ENSG00000141458	ENSG00000141458	HGNC:7897													
NPC1	gene	NPC1	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Niemann-Pick disease, MIM# 257220;Parkinsonism				24035292;30369906		False	3	100;0;0	3.65	True		ENSG00000141458	ENSG00000141458	HGNC:7897													
NPC2	gene	NPC2	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Niemann Pick C2, OMIM 607625;Parkinsonism				PMID: 35695805		False	3	100;0;0	3.65	True		ENSG00000119655	ENSG00000119655	HGNC:14537													
NPC2	gene	NPC2	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Niemann-Pick disease, type C2 MONDO:0011873;Dystonia				34993563;17470133		False	3	100;0;0	3.65	True		ENSG00000119655	ENSG00000119655	HGNC:14537													
NR4A2	gene	NR4A2	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Intellectual developmental disorder with language impairment and early-onset DOPA-responsive dystonia-parkinsonism, MIM# 619911				31922365		False	3	100;0;0	3.65	True		ENSG00000153234	ENSG00000153234	HGNC:7981													
NR4A2	gene	NR4A2	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Intellectual developmental disorder with language impairment and early-onset DOPA-responsive dystonia-parkinsonism, MIM# 619911				31922365		False	3	100;0;0	3.65	True		ENSG00000153234	ENSG00000153234	HGNC:7981													
NUS1	gene	NUS1	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	"Intellectual developmental disorder, autosomal dominant 55, with seizures, MIM#	617831;Parkinsonism;Developmental delay;Intellectual disability;Ataxia;Myoclonus"				PMID: 32485575;30348779		False	3	100;0;0	3.65	True		ENSG00000153989	ENSG00000153989	HGNC:21042													
OPA3	gene	OPA3	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	3-methylglutaconic aciduria, type III, MIM# 258501;developmental delay, hypotonia;dystonia and chorea;ataxia, optic atrophy;spastic paraplegia				20301646;7510656;2494568;11668429		False	3	100;0;0	3.65	True		ENSG00000125741	ENSG00000125741	HGNC:8142													
PANK2	gene	PANK2	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	pantothenate kinase-associated neurodegeneration MONDO:0009319				23447832;20301663		False	3	0;0;0	3.65	True		ENSG00000125779	ENSG00000125779	HGNC:15894													
PANK2	gene	PANK2	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	pantothenate kinase-associated neurodegeneration MONDO:0009319;Dystonia				15911822		False	3	100;0;0	3.65	True		ENSG00000125779	ENSG00000125779	HGNC:15894													
PARK7	gene	PARK7	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	autosomal recessive early-onset Parkinson disease 7 MONDO:0011658				20301402		False	3	100;0;0	3.65	True		ENSG00000116288	ENSG00000116288	HGNC:16369													
PARK7	gene	PARK7	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	"Parkinson disease 7, autosomal recessive early-onset	MIM#606324"				29644727		False	3	100;0;0	3.65	True		ENSG00000116288	ENSG00000116288	HGNC:16369													
PCCA	gene	PCCA	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	"Propionicacidemia, MIM#	606054"				30879957		False	3	100;0;0	3.65	True		ENSG00000175198	ENSG00000175198	HGNC:8653													
PCCB	gene	PCCB	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	"Propionicacidemia, MIM#	606054"				30879957		False	3	100;0;0	3.65	True		ENSG00000114054	ENSG00000114054	HGNC:8654													
PDE10A	gene	PDE10A	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Early onset chorea without epilepsy;infantile onset limb and orofacial dyskinesia (OMIM 616921)				PMID 27058447		False	3	100;0;0	3.65	True		ENSG00000112541	ENSG00000112541	HGNC:8772													
PDE2A	gene	PDE2A	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Paroxysmal dyskinesia;Intellectual developmental disorder with paroxysmal dyskinesia or seizures, MIM# 619150				32467598;32196122;29392776;37317634		False	3	100;0;0	3.65	True		ENSG00000186642	ENSG00000186642	HGNC:8777													
PDE8B	gene	PDE8B	Expert Review Green;Expert Review	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Striatal degeneration, autosomal dominant, MIM#609161				20085714;26769607;26475694		False	3	100;0;0	3.65	True		ENSG00000113231	ENSG00000113231	HGNC:8794													
PDGFB	gene	PDGFB	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Basal ganglia calcification, idiopathic, 5, MIM# 615483;Paroxysmal nonkinesigenic dyskinesia;paroxysmal kinesigenic dyskinesia;Brain calcification				28556368;32443735;23913003		False	3	100;0;0	3.65	True		ENSG00000100311	ENSG00000100311	HGNC:8800													
PDGFB	gene	PDGFB	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Basal ganglia calcification, idiopathic, 5, MIM# 615483				23913003		False	3	100;0;0	3.65	True		ENSG00000100311	ENSG00000100311	HGNC:8800													
PDGFB	gene	PDGFB	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Basal ganglia calcification, idiopathic, 5 615483						False	3	100;0;0	3.65	False		ENSG00000100311	ENSG00000100311	HGNC:8800													
PDGFRB	gene	PDGFRB	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Basal ganglia calcification, idiopathic, 4, MIM# 615007				23255827;30979360		False	3	100;0;0	3.65	True		ENSG00000113721	ENSG00000113721	HGNC:8804													
PDHA1	gene	PDHA1	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)	Pyruvate dehydrogenase E1-alpha deficiency MIM#312170				20002125		False	3	100;0;0	3.65	True		ENSG00000131828	ENSG00000131828	HGNC:8806													
PDHA1	gene	PDHA1	Expert Review Green;Expert Review	Tremors_Superpanel		Neurology and neurodevelopmental disorders	Other	Pyruvate dehydrogenase E1-alpha deficiency, MIM# 312170;Paroxysmal dyskinesia (exercise induced or without clear trigger				20002125;22079328		False	3	100;0;0	3.65	True		ENSG00000131828	ENSG00000131828	HGNC:8806													
PDHX	gene	PDHX	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Lactic acidemia due to PDX1 deficiency, MIM# 245349;episodic dystonia;Paroxysmal dyskinesia (exercise induced or without clear trigger;isolated or with additional features)				16566017;20002125		False	3	100;0;0	3.65	True		ENSG00000110435	ENSG00000110435	HGNC:21350													
PDHX	gene	PDHX	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	"Lacticacidemia due to PDX1 deficiency	MIM#245349"				20002125;16566017;17152059		False	3	100;0;0	3.65	True		ENSG00000110435	ENSG00000110435	HGNC:21350													
PGK1	gene	PGK1	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	X-LINKED: hemizygous mutation in males, biallelic mutations in females	Phosphoglycerate kinase 1 deficiency, MIM# 300653;Haemolytic anaemia;Rhabdomyolysis;Myopathy;Juvenile Parkinsonism;OMIM 300653				PMID: 30975619		False	3	100;0;0	3.65	True		ENSG00000102144	ENSG00000102144	HGNC:8896													
PINK1	gene	PINK1	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Parkinson disease 6, early onset;Dystonia						False	3	0;0;0	3.65	False		ENSG00000158828	ENSG00000158828	HGNC:14581													
PINK1	gene	PINK1	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Parkinson disease 6, early onset MIM#605909				28980524		False	3	100;0;0	3.65	True		ENSG00000158828	ENSG00000158828	HGNC:14581													
PLA2G6	gene	PLA2G6	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Parkinson disease 14, autosomal recessive 612953;PLA2G6-associated neurodegeneration;Neurodegeneration with brain iron accumulation 2B 610217;Infantile neuroaxonal dystrophy 1 256600						False	3	0;0;0	3.65	False		ENSG00000184381	ENSG00000184381	HGNC:9039													
PLA2G6	gene	PLA2G6	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	autosomal recessive Parkinson disease 14 MONDO:0013060				20301718		False	3	100;0;0	3.65	True		ENSG00000184381	ENSG00000184381	HGNC:9039													
PNKD	gene	PNKD	Expert Review Green;Royal Children's Hospital Neurology Department;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Paroxysmal nonkinesigenic dyskinesia 1, MIM# 118800						False	3	100;0;0	3.65	True		ENSG00000127838	ENSG00000127838	HGNC:9153													
PNKD	gene	PNKD	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Paroxysmal nonkinesigenic dyskinesia 1, MIM# 118800;MONDO:0007326				15262732;15496428;15824259;19124534;21487022		False	3	100;0;0	3.65	True		ENSG00000127838	ENSG00000127838	HGNC:9153													
PNKP	gene	PNKP	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	"Ataxia-oculomotor apraxia 4, MIM#	616267"				28552035;25728773		False	3	100;0;0	3.65	True		ENSG00000039650	ENSG00000039650	HGNC:9154													
PNPLA8	gene	PNPLA8	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Complex neurodevelopmental disorder, MONDO:0100038, PNPLA8-related				PMID: 39082157		False	3	100;0;0	3.65	True		ENSG00000135241	ENSG00000135241	HGNC:28900													
POLG	gene	POLG	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	autosomal dominant progressive external ophthalmoplegia MONDO:0008003				20301791;15351195		False	3	100;0;0	3.65	True		ENSG00000140521	ENSG00000140521	HGNC:9179													
POLR3A	gene	POLR3A	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	"Leukodystrophy, hypomyelinating, 7, with or without oligodontia and/or hypogonadotropic hypogonadism, MIM#	607694;Striatal abnormalities;Dystonia"				32600288;32373668;31940116;31932101;29618326		False	3	100;0;0	3.65	True		ENSG00000148606	ENSG00000148606	HGNC:30074													
POLR3A	gene	POLR3A	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Leukodystrophy, hypomyelinating, 7, with or without oligodontia and/or hypogonadotropic hypogonadism, MIM# 607694;POLR3A Leukoencephalopathy;Parkinsonism;Ocular and dental abnormality;Hypogonadism				PMID: 33652360		False	3	100;0;0	3.65	True		ENSG00000148606	ENSG00000148606	HGNC:30074													
PPP2R5D	gene	PPP2R5D	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Early onset Parkinsonism;Houge-Janssens syndrome 1, MIM#616355				33338668;32743835		False	3	100;0;0	3.65	True		ENSG00000112640	ENSG00000112640	HGNC:9312													
PRKCG	gene	PRKCG	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Spinocerebellar ataxia 14, MIM# 605361;Myoclonus;Parkinsonism				PMID: 29603387		False	3	100;0;0	3.65	True		ENSG00000126583	ENSG00000126583	HGNC:9402													
PRKN	gene	PRKN	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	autosomal recessive juvenile Parkinson disease 2 MONDO:0010820						False	3	100;0;0	3.65	True		ENSG00000185345	ENSG00000185345	HGNC:8607													
PRKN	gene	PRKN	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	juvenile parkinsonism/dystonia;Parkinson disease, juvenile, type 2;Dystonia						False	3	0;0;0	3.65	False		ENSG00000185345	ENSG00000185345	HGNC:8607													
PRKRA	gene	PRKRA	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Dystonia 16, MIM# 612067;MONDO:0012789				18243799;25142429;29279192		False	3	100;0;0	3.65	True		ENSG00000180228	ENSG00000180228	HGNC:9438													
PRKRA	gene	PRKRA	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	dystonia 16 MONDO:0012789				33502045		False	3	100;0;0	3.65	True		ENSG00000180228	ENSG00000180228	HGNC:9438													
PRNP	gene	PRNP	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	inherited Creutzfeldt-Jakob disease MONDO:0007403;Gerstmann-Straussler-Scheinker syndrome MONDO:0007656				20301407		False	3	100;0;0	3.65	True		ENSG00000171867	ENSG00000171867	HGNC:9449													
PRRT2	gene	PRRT2	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Episodic kinesigenic dyskinesia 1, MIM# 128200;MONDO:0007494				22101681;22120146;22744660;22399141		False	3	100;0;0	3.65	True		ENSG00000167371	ENSG00000167371	HGNC:30500													
PRRT2	gene	PRRT2	Expert Review Green;Royal Children's Hospital Neurology Department;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Convulsions, familial infantile, with paroxysmal choreoathetosis 602066;Episodic kinesigenic dyskinesia 1 128200;Seizures, benign familial infantile, 2 605751				33126500		False	3	100;0;0	3.65	True		ENSG00000167371	ENSG00000167371	HGNC:30500													
PSAP	gene	PSAP	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Parkinson disease 24, autosomal dominant, susceptibility to, MIM# 619491				32201884		False	3	100;0;0	3.65	True		ENSG00000197746	ENSG00000197746	HGNC:9498													
PSEN1	gene	PSEN1	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Alzheimer disease 3 MONDO:0011913				3548932;34843019;36825052		False	3	100;0;0	3.65	True		ENSG00000080815	ENSG00000080815	HGNC:9508													
PSEN1	gene	PSEN1	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Frontotemporal dementia, MIM# 600274;Dystonia				28664294;12810495;15159497;29316780		False	3	100;0;0	3.65	True		ENSG00000080815	ENSG00000080815	HGNC:9508													
PSMF1	gene	PSMF1	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Complex neurodevelopmental disorder with motor features, MONDO:0100516, PSMF1-related				https://www.medrxiv.org/content/10.1101/2024.06.19.24308302v1		False	3	100;0;0	3.65	True		ENSG00000125818	ENSG00000125818	HGNC:9571													
PTRHD1	gene	PTRHD1	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Neurodevelopmental disorder with early-onset parkinsonism and behavioral abnormalities, MIM# 620747				27753167;27134041;30398675;29143421		False	3	100;0;0	3.65	True		ENSG00000184924	ENSG00000184924	HGNC:33782													
PTS	gene	PTS	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal							False	3	100;0;0	3.65	True		ENSG00000150787	ENSG00000150787	HGNC:9689													
PTS	gene	PTS	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Hyperphenylalaninemia, BH4-deficient, A, 261640;6-Pyruvoyltetrahydropterin Synthase Deficiency;Dystonia						False	3	0;0;0	3.65	False		ENSG00000150787	ENSG00000150787	HGNC:9689													
QDPR	gene	QDPR	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Hyperphenylalaninemia, BH4-deficient, C, MIM#261630;Dehydropteridin reductase deficiency, Infantile-onset dystonia;Parkinsonism;Epilepsy;Autonomic dysfunction;Hyperphenylalaninemia				PMID: 28413401		False	3	100;0;0	3.65	True		ENSG00000151552	ENSG00000151552	HGNC:9752													
QDPR	gene	QDPR	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Hyperphenylalaninemia, BH4-deficient, C, 261630;Dihydropteridine reductase deficiency;Dystonia						False	3	0;0;0	3.65	False		ENSG00000151552	ENSG00000151552	HGNC:9752													
RAB39B	gene	RAB39B	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	X-LINKED: hemizygous mutation in males, biallelic mutations in females	Early-onset parkinsonism-intellectual disability syndrome MONDO:0010709				25434005;26399558;26739247		False	3	100;0;0	3.65	True		ENSG00000155961	ENSG00000155961	HGNC:16499													
RHOBTB2	gene	RHOBTB2	Expert Review Green;Other	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	"Epileptic encephalopathy, early infantile, 64, MIM#	618004;Paroxysmal movement disorder"				PMID 29276004		False	3	100;0;0	3.65	True		ENSG00000008853	ENSG00000008853	HGNC:18756													
RHOBTB2	gene	RHOBTB2	Expert Review Green;Other	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	"Epileptic encephalopathy, early infantile, 64, MIM#	618004;Dystonia, hypertonia, movement disorder;truncal hypotonia;hemiparesis;developmental and epileptic encephalopathy"				PMID: 29276004		False	3	0;0;0	3.65	True		ENSG00000008853	ENSG00000008853	HGNC:18756													
RNASEH2B	gene	RNASEH2B	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Aicardi-Goutieres syndrome 2 MIM#610181				20131292;26860721		False	3	100;0;0	3.65	True		ENSG00000136104	ENSG00000136104	HGNC:25671													
RNASEH2C	gene	RNASEH2C	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Aicardi-Goutieres syndrome 3 MIM#610329				20131292;23322642		False	3	100;0;0	3.65	True		ENSG00000172922	ENSG00000172922	HGNC:24116													
RNU7-1	gene	RNU7-1	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Aicardi-Goutieres syndrome 9, MIM# 619487				33230297		False	3	100;0;0	3.65	True		ENSG00000238923	ENSG00000238923	HGNC:34033													
SCN1A	gene	SCN1A	Royal Children's Hospital Neurology Department;Expert Review Green;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	Unknown							False	3	0;0;0	3.65	False		ENSG00000144285	ENSG00000144285	HGNC:10585													
SCN1A	gene	SCN1A	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Dravet syndrome, MIM# 607208;Epilepsy, Paekinsonism				PMID: 28186331;24850485		False	3	100;0;0	3.65	True		ENSG00000144285	ENSG00000144285	HGNC:10585													
SCN2A	gene	SCN2A	Royal Children's Hospital Neurology Department;Expert Review Green;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	Unknown							False	3	0;0;0	3.65	False		ENSG00000136531	ENSG00000136531	HGNC:10588													
SCN4A	gene	SCN4A	Royal Children's Hospital Neurology Department;Expert Review Green;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	Unknown							False	3	0;0;0	3.65	False		ENSG00000007314	ENSG00000007314	HGNC:10591													
SCN8A	gene	SCN8A	Expert Review Green;Royal Children's Hospital Neurology Department;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Complex neurodevelopmental disorder MONDO:0100038				26677014;29356177;25799905		False	3	100;0;0	3.65	True		ENSG00000196876	ENSG00000196876	HGNC:10596													
SERAC1	gene	SERAC1	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	3-MEthylGlutaconic aciduria, Dystonia-Deafness, Hepatopathy, Encephalopathy, Leigh-like syndrome;3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome, 614739;Lesions in the basal ganglia						False	3	0;0;0	3.65	False		ENSG00000122335	ENSG00000122335	HGNC:21061													
SERAC1	gene	SERAC1	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome, MIM# 614739;Parkinsonism				PMID: 29332177;16527507		False	3	100;0;0	3.65	True		ENSG00000122335	ENSG00000122335	HGNC:21061													
SETX	gene	SETX	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	"Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2, MIM#	606002"				19696032		False	3	100;0;0	3.65	True		ENSG00000107290	ENSG00000107290	HGNC:445													
SGCE	gene	SGCE	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, maternally imprinted (paternal allele expressed)	Dystonia-11, myoclonic, MIM# 159900;MONDO:0008044				11528394;12821748;16227522		False	3	100;0;0	3.65	True		ENSG00000127990	ENSG00000127990	HGNC:10808													
SHQ1	gene	SHQ1	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Dystonia 35, childhood-onset , MIM# 619921;Neurodevelopmental disorder with dystonia and seizures, MIM# 619922				34542157;29178645;36847845;37475611		False	3	100;0;0	3.65	True		ENSG00000144736	ENSG00000144736	HGNC:25543													
SHQ1	gene	SHQ1	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Dystonia 35, childhood-onset , MIM# 619921				34542157;37475611		False	3	100;0;0	3.65	True		ENSG00000144736	ENSG00000144736	HGNC:25543													
SLC16A2	gene	SLC16A2	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	X-LINKED: hemizygous mutation in males, biallelic mutations in females	Allan-Herndon-Dudley syndrome, MIM# 300523;paroxysmal dyskinesia (passive movement trigger);neurodevelopmental disability, hypotonia				15980113;31410843;20301789		False	3	100;0;0	3.65	True		ENSG00000147100	ENSG00000147100	HGNC:10923													
SLC16A2	gene	SLC16A2	Expert Review Green;Expert Review	Tremors_Superpanel		Neurology and neurodevelopmental disorders	X-LINKED: hemizygous mutation in males, biallelic mutations in females	Allan-Herndon-Dudley syndrome, MIM# 300523				15980113;31410843;20301789		False	3	100;0;0	3.65	True		ENSG00000147100	ENSG00000147100	HGNC:10923													
SLC18A2	gene	SLC18A2	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Parkinsonism-dystonia, infantile, 2 , MIM# 618049;Brain dopamine-serotonin transport disease, Childhood-onset parkinsonism				33983693;23363473;31240161;26497564		False	3	100;0;0	3.65	True		ENSG00000165646	ENSG00000165646	HGNC:10935													
SLC18A2	gene	SLC18A2	Expert Review Green;Expert Review	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	"Parkinsonism-dystonia, infantile, 2, MIM#	618049"				23363473;31240161;26497564		False	3	100;0;0	3.65	True		ENSG00000165646	ENSG00000165646	HGNC:10935													
SLC19A3	gene	SLC19A3	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Thiamine metabolism dysfunction syndrome 2 (biotin- or thiamine-responsive encephalopathy type 2), MIM# 607483;Childhood onset Dystonia and Parkinsonism				PMID: 24260777		False	3	100;0;0	3.65	True		ENSG00000135917	ENSG00000135917	HGNC:16266													
SLC19A3	gene	SLC19A3	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Thiamine metabolism dysfunction syndrome 2 (biotin- or thiamine-responsive encephalopathy type 2) 607483;Dystonia						False	3	0;0;0	3.65	False		ENSG00000135917	ENSG00000135917	HGNC:16266													
SLC1A3	gene	SLC1A3	Expert Review Green;Royal Children's Hospital Neurology Department;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Episodic ataxia, type 6, MIM# 612656				19139306;16116111;29208948;27829685		False	3	100;0;0	3.65	True		ENSG00000079215	ENSG00000079215	HGNC:10941													
SLC20A2	gene	SLC20A2	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Basal ganglia calcification, idiopathic, 1 213600;Dystonia				22327515;23334463;24411498		False	3	100;0;0	3.65	True		ENSG00000168575	ENSG00000168575	HGNC:10947													
SLC20A2	gene	SLC20A2	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Basal ganglia calcification, idiopathic, 1, MIM# 213600				22327515;23334463		False	3	100;0;0	3.65	True		ENSG00000168575	ENSG00000168575	HGNC:10947													
SLC2A1	gene	SLC2A1	Expert Review Green;Royal Children's Hospital Neurology Department;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	GLUT1 deficiency syndrome MONDO:0000188				18451999;34279792;18577546;34305802;27098784		False	3	100;0;0	3.65	True		ENSG00000117394	ENSG00000117394	HGNC:11005													
SLC2A1	gene	SLC2A1	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Dystonia 9, MIM# 601042;MONDO:0010983						False	3	100;0;0	3.65	True		ENSG00000117394	ENSG00000117394	HGNC:11005													
SLC30A10	gene	SLC30A10	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	cirrhosis - dystonia - polycythemia - hypermanganesemia syndrome MONDO:0013208				22341971;22341972		False	3	100;0;0	3.65	True		ENSG00000196660	ENSG00000196660	HGNC:25355													
SLC30A10	gene	SLC30A10	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Dystonia/Parkinsonism, Hypermanganesemia, Polycythemia, and Chronic Liver Disease;Hypermanganesemia with dystonia, polycythemia, and cirrhosis, 613280						False	3	0;0;0	3.65	False		ENSG00000196660	ENSG00000196660	HGNC:25355													
SLC30A9	gene	SLC30A9	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	"Birk-Landau-Perez syndrome	(MIM#617595)"				37041080		False	3	100;0;0	3.65	True		ENSG00000014824	ENSG00000014824	HGNC:1329													
SLC39A14	gene	SLC39A14	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Hypermanganesemia with dystonia 2 (MIM# 617013)				27231142;32626807;29685658;30232769		False	3	100;0;0	3.65	True		ENSG00000104635	ENSG00000104635	HGNC:20858													
SLC39A14	gene	SLC39A14	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Hypermanganesemia with dystonia 2 617013						False	3	0;0;0	3.65	False		ENSG00000104635	ENSG00000104635	HGNC:20858													
SLC6A3	gene	SLC6A3	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Parkinsonism-dystonia, infantile, 1, MIM# 613135				21112253		False	3	100;0;0	3.65	True		ENSG00000142319	ENSG00000142319	HGNC:11049													
SLC6A3	gene	SLC6A3	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Dopamine transporter deficiency;Parkinsonism-dystonia, infantile, 613135						False	3	0;0;0	3.65	False		ENSG00000142319	ENSG00000142319	HGNC:11049													
SLC6A5	gene	SLC6A5	Expert Review Green;Royal Children's Hospital Neurology Department;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Hyperekplexia 3, MIM# 614618				31604777;30847549;29859229;16751771		False	3	100;0;0	3.65	True		ENSG00000165970	ENSG00000165970	HGNC:11051													
SNCA	gene	SNCA	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Dementia, Lewy body (MIM#127750);Parkinson disease 1 (MIM#168601);Parkinson disease 4 (MIM#605543)				32849182;26858591;32740728		False	3	100;0;0	3.65	True		ENSG00000145335	ENSG00000145335	HGNC:11138													
SNORD118	gene	SNORD118	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Leukoencephalopathy, brain calcifications, and cysts MIM#614561				27571260		False	3	100;0;0	3.65	True		ENSG00000200463	ENSG00000200463	HGNC:32952													
SOX6	gene	SOX6	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	"Tolchin-Le Caignec syndrome, MIM#	618971;Developmental delay;ID;ASD;ADHD;Parkinsonism;Syringomyelia"				24453155;25127144		False	3	100;0;0	3.65	True		ENSG00000110693	ENSG00000110693	HGNC:16421													
SPATA5L1	gene	SPATA5L1	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Neurodevelopmental disorder with hearing loss and spasticity, MIM# 619616				34626583		False	3	100;0;0	3.65	True		ENSG00000171763	ENSG00000171763	HGNC:28762													
SPG11	gene	SPG11	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	hereditary spastic paraplegia 11 MONDO:0011445				35036589;23121729;21381113;27217339		False	3	100;0;0	3.65	True		ENSG00000104133	ENSG00000104133	HGNC:11226													
SPG7	gene	SPG7	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	"Spastic paraplegia 7, autosomal recessive, MIM#	607259;Ataxia;Progressive external opthalmoplegia;Parkinsonism"				PMID: 31433872		False	3	100;0;0	3.65	True		ENSG00000197912	ENSG00000197912	HGNC:11237													
SPR	gene	SPR	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Dystonia, dopa-responsive, due to sepiapterin reductase deficiency, MIM# 612716;MONDO:0012994				11443547;18502672;22522443;16532389;31777525;29147684;28189489		False	3	100;0;0	3.65	True		ENSG00000116096	ENSG00000116096	HGNC:11257													
SPR	gene	SPR	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Dopa-responsive dystonia due to sepiapterin reductase deficiency MONDO:0012994				22522443;11920285;14663042;16443856;21782285;32813147		False	3	0;100;0	3.65	True		ENSG00000116096	ENSG00000116096	HGNC:11257													
SQSTM1	gene	SQSTM1	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Neurodegeneration with ataxia, dystonia, and gaze palsy, childhood-onset, MIM# 617145				PMID: 27545679		False	3	100;0;0	3.65	True		ENSG00000161011	ENSG00000161011	HGNC:11280													
STUB1	gene	STUB1	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Spinocerebellar Ataxia 48, OMIM 618093;Parkinsonism				30381368;32285148;32337344		False	3	100;0;0	3.65	True		ENSG00000103266	ENSG00000103266	HGNC:11427													
STXBP1	gene	STXBP1	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Developmental and epileptic encephalopathy 4, MIM# 612164;Juvenile onset Parkinsonism				25418441;32643187;29929108		False	3	100;0;0	3.65	True		ENSG00000136854	ENSG00000136854	HGNC:11444													
SUCLA2	gene	SUCLA2	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Mitochondrial DNA depletion syndrome 5 (encephalomyopathic with or without methylmalonic aciduria);Dystonia						False	3	0;0;0	3.65	False		ENSG00000136143	ENSG00000136143	HGNC:11448													
SUOX	gene	SUOX	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Sulfite oxidase deficiency MIM#272300				9600976;28933809;16140720		False	3	100;0;0	3.65	True		ENSG00000139531	ENSG00000139531	HGNC:11460													
SURF1	gene	SURF1	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	"Leigh syndrome, due to COX IV deficiency, MIM#	256000"				19780766		False	3	100;0;0	3.65	True		ENSG00000148290	ENSG00000148290	HGNC:11474													
SYNJ1	gene	SYNJ1	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Parkinson disease 20, early-onset, MIM# 615530				23804563;23804577;27496670;33841314		False	3	100;0;0	3.65	True		ENSG00000159082	ENSG00000159082	HGNC:11503													
SYNJ1	gene	SYNJ1	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	juvenile Parkinsonism;Parkinson disease 20, early-onset						False	3	0;0;0	3.65	False		ENSG00000159082	ENSG00000159082	HGNC:11503													
SYT1	gene	SYT1	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Baker-Gordon syndrome MIM#618218				30107533		False	3	100;0;0	3.65	True		ENSG00000067715	ENSG00000067715	HGNC:11509													
TBC1D24	gene	TBC1D24	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Epilepsy, rolandic, with proxysmal exercise-induce dystonia and writer's cramp, MIM# 608105;Episodic dystonia (Exercise induced or without clear trigger);epilepsy;myoclonus;hearing loss				PMID 31257402;PMID 31226716;PMID 25719194		False	3	100;0;0	3.65	True		ENSG00000162065	ENSG00000162065	HGNC:29203													
TBC1D24	gene	TBC1D24	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Developmental and epileptic encephalopathy 16, MIM# 615338;Intellectual disability;Parkinsonism;Seizures;Psychosis				PMID: 28663785;21087195		False	3	100;0;0	3.65	True		ENSG00000162065	ENSG00000162065	HGNC:29203													
TH	gene	TH	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Tyrosine hydroxylase deficiency MONDO:0100064				20301334;20301610		False	3	100;0;0	3.65	True		ENSG00000180176	ENSG00000180176	HGNC:11782													
TH	gene	TH	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Segawa syndrome, recessive, MIM# 605407;MONDO:0011551						False	3	100;0;0	3.65	True		ENSG00000180176	ENSG00000180176	HGNC:11782													
THAP1	gene	THAP1	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal	Dystonia 6, torsion, 602629;Dystonia;MONDO:0011264				21793105;22377579;36205328;21425335;20211909		False	3	100;0;0	3.65	True		ENSG00000131931	ENSG00000131931	HGNC:20856													
TIMM8A	gene	TIMM8A	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	X-LINKED: hemizygous mutation in males, biallelic mutations in females	Deafness-Dystonia-Optic Neuronopathy Syndrome;Mohr-Tranebjaerg syndrome, MIM# 304700				11803487;11405816;32820032		False	3	100;0;0	3.65	True		ENSG00000126953	ENSG00000126953	HGNC:11817													
TMEM151A	gene	TMEM151A	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Paroxysmal Kinesigenic Dyskinesia;episodic kinesigenic dyskinesia MONDO:0044202				34820915;34518509		False	3	100;0;0	3.65	False		ENSG00000179292	ENSG00000179292	HGNC:28497													
TNPO2	gene	TNPO2	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	"Intellectual developmental disorder with hypotonia, impaired speech, and dysmorphic facies, MIM#	619556"				34314705		False	3	100;0;0	3.65	True		ENSG00000105576	ENSG00000105576	HGNC:19998													
TOR1A	gene	TOR1A	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Autosomal dominant or sporadic dystonia (DYT1);Early-Onset Primary Dystonia;Dystonia-1, torsion, 128100				9288096;19955557;18477710;32243914;31583275;31347572		False	3	100;0;0	3.65	True		ENSG00000136827	ENSG00000136827	HGNC:3098													
TPK1	gene	TPK1	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Thiamine metabolism dysfunction syndrome 5 (episodic encephalopathy type);Dystonia						False	3	0;0;0	3.65	False		ENSG00000196511	ENSG00000196511	HGNC:17358													
TPP1	gene	TPP1	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Ceroid lipofuscinosis, neuronal, 2, MIM# 204500;Parkinsonism				PMID: 21940688		False	3	100;0;0	3.65	True		ENSG00000166340	ENSG00000166340	HGNC:2073													
TREX1	gene	TREX1	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Aicardi-Goutieres syndrome 1, dominant and recessive MIM#225750				20131292		False	3	100;0;0	3.65	True		ENSG00000213689	ENSG00000213689	HGNC:12269													
TRPM3	gene	TRPM3	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Neurodevelopmental disorder with hypotonia, dysmorphic facies, and skeletal anomalies, with or without seizures, MIM# 620224				31278393;35146895		False	3	100;0;0	3.65	True		ENSG00000083067	ENSG00000083067	HGNC:17992													
TSPOAP1	gene	TSPOAP1	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Dystonia 22, MIM# 620453				33539324		False	3	100;0;0	3.65	True		ENSG00000005379	ENSG00000005379	HGNC:16831													
TUBB4A	gene	TUBB4A	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	hereditary whispering dysphonia;Dystonia 4, torsion, autosomal dominant, 128101;Dystonia				23424103;23595291;33084096;32943487		False	3	100;0;0	3.65	True		ENSG00000104833	ENSG00000104833	HGNC:20774													
TWNK	gene	TWNK	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal dominant 3 MIM#609286				24076137;22949510;22580846;19353676		False	3	100;0;0	3.65	True		ENSG00000107815	ENSG00000107815	HGNC:1160													
UBTF	gene	UBTF	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Neurodegeneration, childhood-onset, with brain atrophy, MIM# 617672;MONDO:0044701				28777933;29300972		False	3	100;0;0	3.65	True	Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments	ENSG00000108312	ENSG00000108312	HGNC:12511													
UBTF	gene	UBTF	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Neurodegeneration, childhood-onset, with brain atrophy, MIM# 617672;Parkinsonism;Dystonia;Chorea;Brain atrophy				PubMed: 28777933;29300972		False	3	100;0;0	3.65	True		ENSG00000108312	ENSG00000108312	HGNC:12511													
VAC14	gene	VAC14	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Striatonigral degeneration, childhood-onset 617054						False	3	0;0;0	3.65	False		ENSG00000103043	ENSG00000103043	HGNC:25507													
VAC14	gene	VAC14	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Striatonigral degeneration, childhood-onset, MIM# 617054;Dystonia;Parkinsonism				PMID: 31392254;28502045		False	3	100;0;0	3.65	True		ENSG00000103043	ENSG00000103043	HGNC:25507													
VAMP2	gene	VAMP2	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Neurodevelopmental disorder with hypotonia and autistic features with or without hyperkinetic movements 618760;Dystonia;Cortical visual impairment;Seizures;Stereotypic behaviour;Generalized hypotonia;Intellectual disability				30929742		False	3	100;0;0	3.65	True		ENSG00000220205	ENSG00000220205	HGNC:12643													
VCP	gene	VCP	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Inclusion body myopathy with Paget disease of bone and frontotemporal dementia MONDO:0000507				38283104;38145206		False	3	100;0;0	3.65	True	Other	ENSG00000165280	ENSG00000165280	HGNC:12666													
VPS13A	gene	VPS13A	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	complex parkinsonism;Choreoacanthocytosis 200150						False	3	0;0;0	3.65	False		ENSG00000197969	ENSG00000197969	HGNC:1908													
VPS13A	gene	VPS13A	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	chorea-acanthocytosis MONDO:0008695				20301561;37636221		False	3	100;0;0	3.65	True		ENSG00000197969	ENSG00000197969	HGNC:1908													
VPS13C	gene	VPS13C	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Parkinson disease 23, autosomal recessive, early onset MIM#616840				26942284;30452786;28862745		False	3	100;0;0	3.65	True		ENSG00000129003	ENSG00000129003	HGNC:23594													
VPS13D	gene	VPS13D	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	"Spinocerebellar ataxia, autosomal recessive 4, MIM#	607317"				29604224;29518281		False	3	100;0;0	3.65	True		ENSG00000048707	ENSG00000048707	HGNC:23595													
VPS16	gene	VPS16	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Dystonia 30, MIM#619291				32808683		False	3	100;0;0	3.65	True		ENSG00000215305	ENSG00000215305	HGNC:14584													
VPS16	gene	VPS16	Expert Review Green;Expert Review	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Dystonia 30, MIM#619291				33482438;33497487		False	3	100;0;0	3.65	True		ENSG00000215305	ENSG00000215305	HGNC:14584													
VPS35	gene	VPS35	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Parkinson disease 17, MIM# 614203				21763482;21763483;22801713;34704029		False	3	100;0;0	3.65	True		ENSG00000069329	ENSG00000069329	HGNC:13487													
VPS41	gene	VPS41	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Spinocerebellar ataxia-29 (SCAR29), MIM#619389;Progressive neurodevelopmental disorder with ataxia, hypotonia, dystonia, intellectual disability and speech delay				32808683;33764426		False	3	100;0;0	3.65	True		ENSG00000006715	ENSG00000006715	HGNC:12713													
VPS4A	gene	VPS4A	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	CIMDAG syndrome MIM# 619273				33186543;33186545		False	3	100;0;0	3.65	True	Other	ENSG00000132612	ENSG00000132612	HGNC:13488													
WARS2	gene	WARS2	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Parkinsonism-dystonia 3, childhood-onset, MIM# 619738;Neurodevelopmental disorder, mitochondrial, with abnormal movements and lactic acidosis, with or without seizures, MIM# 617710				29120065;31970218;34890876;28236339;28650581;28905505;30920170		False	3	100;0;0	3.65	True		ENSG00000116874	ENSG00000116874	HGNC:12730													
WARS2	gene	WARS2	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Parkinsonism-dystonia 3, childhood-onset, MIM# 619738				PMID: 29120065;34890876;31970218		False	3	100;0;0	3.65	True		ENSG00000116874	ENSG00000116874	HGNC:12730													
WDR45	gene	WDR45	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)	X-linked complex neurodevelopmental disorder MONDO:0100148				28211668		False	3	100;0;0	3.65	True		ENSG00000196998	ENSG00000196998	HGNC:28912													
WDR45	gene	WDR45	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)	Neurodegeneration with brain iron accumulation 5 300894;beta-propeller protein-associated neurodegeneration;Dystonia						False	3	0;0;0	3.65	False		ENSG00000196998	ENSG00000196998	HGNC:28912													
WDR73	gene	WDR73	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Galloway-Mowat syndrome 1, 251300						False	3	0;0;0	3.65	False		ENSG00000177082	ENSG00000177082	HGNC:25928													
XK	gene	XK	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)	McLeod syndrome with or without chronic granulomatous disease MIM#300842				11761473		False	3	100;0;0	3.65	True		ENSG00000047597	ENSG00000047597	HGNC:12811													
XPR1	gene	XPR1	Expert Review Green;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Basal ganglia calcification, idiopathic, 6, MIM# 616413				25938945		False	3	100;0;0	3.65	True		ENSG00000143324	ENSG00000143324	HGNC:12827													
YIF1B	gene	YIF1B	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Kaya-Barakat-Masson syndrome, MIM# 619125;Central hypotonia;Failure to thrive;Microcephaly;Global developmental delay;Intellectual disability;Seizures;Spasticity;Abnormality of movement				32006098;26077767		False	3	100;0;0	3.65	True		ENSG00000167645	ENSG00000167645	HGNC:30511													
YY1	gene	YY1	Expert Review Green;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Gabriele-de Vries syndrome 617557						False	3	0;0;0	3.65	False		ENSG00000100811	ENSG00000100811	HGNC:12856													
ZFYVE26	gene	ZFYVE26	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	"Spastic paraplegia 15, autosomal recessive, MIM#	270700;Spastic paraplegia and retinal degeneration;Kjellin syndrome;Parkinsonism"				PMID: 33033739;21462267		False	3	100;0;0	3.65	True		ENSG00000072121	ENSG00000072121	HGNC:20761													
ZNF526	gene	ZNF526	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Dentici-Novelli neurodevelopmental syndrome, MIM# 619877				21937992;25558065;33397746		False	3	100;0;0	3.65	True		ENSG00000167625	ENSG00000167625	HGNC:29415													
ABAT	gene	ABAT	Expert Review Amber;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	GABA-transaminase deficiency, MIM# 613163;intellectual disability;autism;DEE;epilepsy;paroxysmal dyskinesia				30617166		False	2	0;100;0	3.65	True		ENSG00000183044	ENSG00000183044	HGNC:23													
AFG3L2	gene	AFG3L2	Expert Review Amber;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Spinocerebellar ataxia 28, MIM# 610246;optic atrophy;spastic ataxia;L-dopa-responsive parkinsonism				30252181;36110148		False	2	33;33;33	3.65	True		ENSG00000141385	ENSG00000141385	HGNC:315													
AFG3L2	gene	AFG3L2	Expert Review Amber;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Spastic ataxia 5, autosomal recessive MIM#614487;Early-onset dystonia				22964162;16541453;32219868;36110148		False	2	33;0;67	3.65	True		ENSG00000141385	ENSG00000141385	HGNC:315													
ALK	gene	ALK	Expert Review Amber;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Spastic-dystonic diplegia				PMID: 32989326		False	2	0;100;0	3.65	True		ENSG00000171094	ENSG00000171094	HGNC:427													
APP	gene	APP	Expert Review Amber;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Alzheimer disease 1, familial, MIM# 104300						False	2	0;100;0	3.65	True		ENSG00000142192	ENSG00000142192	HGNC:620													
ATP5B	gene	ATP5B	Expert Review Amber;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Inherited dystonia, MONDO:0044807, ATP5B-related				36860166		False	2	50;50;0	3.65	True		ENSG00000110955	ENSG00000110955	HGNC:830													
ATP7B	gene	ATP7B	Expert Review Amber;Royal Children's Hospital Neurology Department;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Wilson disease, MIM# 277900				32662046		False	2	0;100;0	3.65	True		ENSG00000123191	ENSG00000123191	HGNC:870													
CACNB4	gene	CACNB4	Expert Review Amber;Royal Children's Hospital Neurology Department;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Episodic ataxia, type 5, MIM#613855				10762541;9628818;27003325		False	2	0;100;0	3.65	True		ENSG00000182389	ENSG00000182389	HGNC:1404													
CHD8	gene	CHD8	Expert Review Amber;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Neurodevelopmental disorder, CHD8-related, MIM#615032;Dystonia				34415117		False	2	0;100;0	3.65	True		ENSG00000100888	ENSG00000100888	HGNC:20153													
CIZ1	gene	CIZ1	Expert Review Amber;Royal Melbourne Hospital	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Dystonia 23, 614860				27163549;29154038;22447717		False	2	0;100;0	3.65	True		ENSG00000148337	ENSG00000148337	HGNC:16744													
COASY	gene	COASY	Expert Review Amber;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Neurodegeneration with brain iron accumulation 6, MIM# 615643				28489334;24360804		False	2	0;100;0	3.65	True		ENSG00000068120	ENSG00000068120	HGNC:29932													
COL6A3	gene	COL6A3	Expert Review Amber;Royal Melbourne Hospital;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Dystonia 27, MIM#616411				26004199;32037012;26872670;32037012		False	2	50;50;0	3.65	True		ENSG00000163359	ENSG00000163359	HGNC:2213													
DDC	gene	DDC	Expert Review Amber;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Aromatic L-amino acid decarboxylase deficiency, MIM# 608643;Infantile-onset parkinsonism & dystonia;Bulbar dysfunction;Oculogyric crisis;Autonomic dysfunction;Intellectual disability				PMID: 33983693		False	2	50;50;0	3.65	True		ENSG00000132437	ENSG00000132437	HGNC:2719													
DHDDS	gene	DHDDS	Expert Review Amber;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Developmental delay and seizures with or without movement abnormalities, MIM# 617836;Myoclonic Epilepsy;Parkinsonism;Ataxia;Intellectual disability				PMID: 34837344;29100083		False	2	50;50;0	3.65	True		ENSG00000117682	ENSG00000117682	HGNC:20603													
EPM2A	gene	EPM2A	Expert Review Amber;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Epilepsy, progressive myoclonic 2A (Lafora), MIM# 254780;Progressive Myoclonic Epilepsy;Parkinsonism				27574708;28818698		False	2	50;50;0	3.65	True		ENSG00000112425	ENSG00000112425	HGNC:3413													
FBXL4	gene	FBXL4	Expert Review Amber;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Mitochondrial DNA depletion syndrome 13 (encephalomyopathic type) MIM#615471						False	2	0;100;0	3.65	True		ENSG00000112234	ENSG00000112234	HGNC:13601													
GSX2	gene	GSX2	Expert Review Amber;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	"Diencephalic-mesencephalic junction dysplasia syndrome 2	618646;Intellectual disability;Dystonia;Spastic tetra paresis"				31412107		False	2	0;100;0	3.65	True		ENSG00000180613	ENSG00000180613	HGNC:24959													
HACE1	gene	HACE1	Expert Review Amber;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Spastic paraplegia and psychomotor retardation with or without seizures MIM#616756				26424145;26437029		False	2	0;100;0	3.65	True		ENSG00000085382	ENSG00000085382	HGNC:21033													
JPH3	gene	JPH3	Expert Review Amber;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	paroxysmal dystonia, intellectual disability				PMID: 36273396		False	2	50;50;0	3.65	True		ENSG00000154118	ENSG00000154118	HGNC:14203													
KCNQ2	gene	KCNQ2	Expert Review Amber;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Epileptic encephalopathy, early infantile, 7 MIM#613720				12742592;32585800		False	2	0;100;0	3.65	True		ENSG00000075043	ENSG00000075043	HGNC:6296													
KIF1C	gene	KIF1C	Expert Review Amber;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	"Spastic ataxia 2, autosomal recessive, MIM#	611302"				31413903		False	2	0;100;0	3.65	True		ENSG00000129250	ENSG00000129250	HGNC:6317													
KIF5A	gene	KIF5A	Expert Review Amber;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Spastic paraplegia 10, autosomal dominant MIM#604187				18853458		False	2	0;100;0	3.65	True		ENSG00000155980	ENSG00000155980	HGNC:6323													
MAPT	gene	MAPT	Expert Review Amber;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Dementia, frontotemporal, with or without parkinsonism MIM#600274				17319286;15883319		False	2	0;100;0	3.65	True		ENSG00000186868	ENSG00000186868	HGNC:6893													
NBEA	gene	NBEA	Expert Review Amber;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Neurodevelopmental disorder with or without early-onset generalized epilepsy, MIM# 619157;Paroxysmal Kinesigenic Dyskinesia;DEE;autism;intellectual disability				33692494		False	2	0;100;0	3.65	True		ENSG00000172915	ENSG00000172915	HGNC:7648													
NHLRC1	gene	NHLRC1	Expert Review Amber;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Epilepsy, progressive myoclonic 2B (Lafora), MIM# 254780;Lafora disease;Progressive Myoclonic Epilepsy;Parkinsonism				22425593;32301727		False	2	50;50;0	3.65	True		ENSG00000187566	ENSG00000187566	HGNC:21576													
NUP54	gene	NUP54	Expert Review Amber;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Dystonia 37, early-onset, with striatal lesions, MIM# 620427;Early onset dystonia;progressive neurological deterioration;ataxia;dysarthria;dysphagia;hypotonia				36333996		False	2	0;100;0	3.65	True		ENSG00000138750	ENSG00000138750	HGNC:17359													
PNPLA6	gene	PNPLA6	Expert Review Amber;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	PNPLA6-related spastic paraplegia with or without ataxia MONDO:0100149				32623594;36825042		False	2	0;100;0	3.65	True		ENSG00000032444	ENSG00000032444	HGNC:16268													
PRKN	gene	PRKN	Expert Review Amber;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Parkinson disease, juvenile, type 2 MIM#600116;paroxysmal exercise induced dyskinesia;fasting induced dyskinesia;early onset parkinsonism				37205242		False	2	0;100;0	3.65	True		ENSG00000185345	ENSG00000185345	HGNC:8607													
PTPA	gene	PTPA	Expert Review Amber;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Intellectual disability, MONDO: 36073231, PTPA-related;Parkisonism				36073231;37448355		False	2	0;100;0	3.65	True		ENSG00000119383	ENSG00000119383	HGNC:9308													
RAB32	gene	RAB32	Expert Review Amber;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	{Parkinson disease 26, autosomal dominant, susceptibility to}, MIM# 620923				38614108;38858457		False	2	0;50;50	3.65	True	Other	ENSG00000118508	ENSG00000118508	HGNC:9772													
SAMHD1	gene	SAMHD1	Expert Review Amber;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Aicardi-Goutieres syndrome 5 MIM#612952				20131292		False	2	0;100;0	3.65	True		ENSG00000101347	ENSG00000101347	HGNC:15925													
SHQ1	gene	SHQ1	Expert Review Amber;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Neurodevelopmental disorder with dystonia and seizures, MIM# 619922				36847845		False	2	50;50;0	3.65	True		ENSG00000144736	ENSG00000144736	HGNC:25543													
SPR	gene	SPR	Expert Review Amber;Royal Children's Hospital Neurology Department;Victorian Clinical Genetics Services	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Dopa-responsive dystonia due to sepiapterin reductase deficiency MONDO:0012994				32591469		False	2	0;100;0	3.65	True		ENSG00000116096	ENSG00000116096	HGNC:11257													
UQCRC1	gene	UQCRC1	Expert Review Amber;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Parkinsonism with polyneuropathy, MIM# 619279				33141179;33248804		False	2	0;100;0	3.65	True		ENSG00000010256	ENSG00000010256	HGNC:12585													
VAMP1	gene	VAMP1	Expert Review Amber;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	"Spastic ataxia 1, autosomal dominant, MIM#	108600"				22958904		False	2	0;100;0	3.65	True		ENSG00000139190	ENSG00000139190	HGNC:12642													
XPR1	gene	XPR1	Expert Review Amber;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Basal ganglia calcification, idiopathic, 6, MIM# 616413;brain calcification;basal ganglia calcification;paroxysmal dyskinesia;epilepsy;DEE				33433330		False	2	0;100;0	3.65	True		ENSG00000143324	ENSG00000143324	HGNC:12827													
ATXN1_CAG	str	ATXN1	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Spinocerebellar Ataxia type 1;Parkinsonism;OMIM 164400				" 	PMID: 24602359"		False	3	100;0;0	3.65	True		ENSG00000124788	ENSG00000124788	HGNC:10548	6	16327867	16327953	16327636	16327722	CAG	36	45					
FTDALS	str	C9orf72	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Frontotemporal dementia and/or amyotrophic lateral sclerosis 1 MIM#105550				25577942;21944779;21944778;31779815		False	3	100;0;0	3.65	True		ENSG00000147894	ENSG00000147894	HGNC:28337	9	27573427	27573544	27573529	27573546	GGGGCC	25	60					
FTDALS	str	C9orf72	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Frontotemporal dementia and/or amyotrophic lateral sclerosis 1 MIM#105550				26166205;24363131;26187722;25577942;21944779;21944778		False	3	100;0;0	3.65	True		ENSG00000147894	ENSG00000147894	HGNC:28337	9	27573427	27573544	27573529	27573546	GGGGCC	25	60					
FXTAS	str	FMR1	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)	Fragile X tremor/ataxia syndrome MIM#300623				27340021;28176767;20301558;23765048;25227148;11445641		False	3	100;0;0	3.65	True		ENSG00000102081	ENSG00000102081	HGNC:3775	X	146993569	146993628	147912051	147912110	CGG	44	55					
HD	str	HTT	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Huntington disease MIM#143100				20301482;29325606		False	3	100;0;0	3.65	False		ENSG00000197386	ENSG00000197386	HGNC:4851	4	3076604	3076666	3074877	3074939	CAG	26	40					
NIID	str	NOTCH2NL	Expert Review Green;Literature	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Neuronal intranuclear inclusion disease MIM#603472;Oculopharyngodistal myopathy 3 MIM#619473;Tremor, hereditary essential, 6 MIM#618866				31178126;31332381;31819945;33887199;33943039;32250060;31332380;32852534;32989102;34333668		False	3	100;0;0	3.65	True		ENSG00000213240	ENSG00000264343	HGNC:31862	1	145209324	145209344	149390803	149390829	GGC	40	60					
XDP	str	TAF1	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	X-LINKED: hemizygous mutation in males, biallelic mutations in females	Dystonia-Parkinsonism, X-linked MIM#314250				17273961;29229810		False	3	100;0;0	3.65	True		ENSG00000147133	ENSG00000147133	HGNC:11535	X	70672905	70672979	71453055	71453129	CCCTCT	13	30					
XDP	str	TAF1	Expert Review Green;Expert list	Tremors_Superpanel		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Dystonia-Parkinsonism, X-linked MIM#314250				17273961;29229810		False	3	100;0;0	3.65	True		ENSG00000147133	ENSG00000147133	HGNC:11535	X	70672905	70672979	71453055	71453129	CCCTCT	13	30