Entity Name	Entity type	Gene Symbol	Sources(; separated)	Level4	Level3	Level2	Model_Of_Inheritance	Phenotypes	Omim	Orphanet	HPO	Publications	Description	Flagged	GEL_Status	UserRatings_Green_amber_red	version	ready	Mode of pathogenicity	EnsemblId(GRch37)	EnsemblId(GRch38)	HGNC	Position Chromosome	Position GRCh37 Start	Position GRCh37 End	Position GRCh38 Start	Position GRCh38 End	STR Repeated Sequence	STR Normal Repeats	STR Pathogenic Repeats	Region Haploinsufficiency Score	Region Triplosensitivity Score	Region Required Overlap Percentage	Region Variant Type	Region Verbose Name
APC	gene	APC	Expert Review Green;SA Pathology	Medulloblastoma		Cancer Predisposition	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Medulloblastoma, MONDO:0007959;Familial adenomatous polyposis 1, MONDO:0021056;Adenomatous polyposis coli, MIM#175100			Medulloblastoma;HP:0002885			False	3	100;0;0	1.1	True		ENSG00000134982	ENSG00000134982	HGNC:583													
BRCA2	gene	BRCA2	Expert list;Expert Review;Expert Review Green	Medulloblastoma		Cancer Predisposition	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Medulloblastoma, MONDO:0007959;BRCA2-related cancer predisposition, MONDO:0700269;Breast-ovarian cancer, familial, 2, MIM#612555			Medulloblastoma;HP:0002885			False	3	100;0;0	1.1	True		ENSG00000139618	ENSG00000139618	HGNC:1101													
ELP1	gene	ELP1	Expert Review;Expert Review Green	Medulloblastoma		Cancer Predisposition	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Medulloblastoma, MONDO:0007959;Medulloblastoma predisposition syndrome, MIM#155255			Medulloblastoma;HP:0002885	32296180;39184053		False	3	100;0;0	1.1	True		ENSG00000070061	ENSG00000070061	HGNC:5959													
EPCAM	gene	EPCAM	Expert list;Expert Review;Expert Review Green	Medulloblastoma		Cancer Predisposition	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Medulloblastoma, MONDO:0007959;Lynch syndrome 8, MONDO:0013196;Lynch syndrome 8, MIM#613244			Medulloblastoma;HP:0002885			False	3	100;0;0	1.1	True		ENSG00000119888	ENSG00000119888	HGNC:11529													
GPR161	gene	GPR161	Expert Review;Expert Review Green	Medulloblastoma		Cancer Predisposition	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Medulloblastoma, MONDO:0007959;Medulloblastoma predisposition syndrome, MIM#155255			Medulloblastoma;HP:0002885	31609649;39184053		False	3	100;0;0	1.1	True		ENSG00000143147	ENSG00000143147	HGNC:23694													
MLH1	gene	MLH1	Expert list;Expert Review;Expert Review Green	Medulloblastoma		Cancer Predisposition	BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal	Medulloblastoma, MONDO:0007959;Lynch syndrome 2, MONDO:0012249;Mismatch repair cancer syndrome 1, MONDO:0010159;Lynch syndrome 2, MIM#609310;Mismatch repair cancer syndrome 1, MIM#276300			Medulloblastoma;HP:0002885			False	3	100;0;0	1.1	True		ENSG00000076242	ENSG00000076242	HGNC:7127													
MSH2	gene	MSH2	Expert list;Expert Review;Expert Review Green	Medulloblastoma		Cancer Predisposition	BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal	Medulloblastoma, MONDO:0007959;Lynch syndrome 1, MONDO:0007356;Mismatch repair cancer syndrome 2, MONDO:0030840;Lynch syndrome 1, MIM#120435;Mismatch repair cancer syndrome 2, MIM#619096			Medulloblastoma;HP:0002885			False	3	100;0;0	1.1	True		ENSG00000095002	ENSG00000095002	HGNC:7325													
MSH6	gene	MSH6	Expert list;Expert Review;Expert Review Green	Medulloblastoma		Cancer Predisposition	BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal	Medulloblastoma, MONDO:0007959;Lynch syndrome 5, MONDO:0013710;Mismatch repair cancer syndrome 3, MONDO:0030841;Lynch syndrome 5, MIM#614350;Mismatch repair cancer syndrome 3, MIM#619097			Medulloblastoma;HP:0002885			False	3	100;0;0	1.1	True		ENSG00000116062	ENSG00000116062	HGNC:7329													
PMS2	gene	PMS2	Expert list;Expert Review;Expert Review Green	Medulloblastoma		Cancer Predisposition	BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal	Medulloblastoma, MONDO:0007959;Lynch syndrome 4, MONDO:0013699;Mismatch repair cancer syndrome 4, MONDO:0030843;Lynch syndrome 4, MIM#614337;Mismatch repair cancer syndrome 4, MIM#619101			Medulloblastoma;HP:0002885			False	3	100;0;0	1.1	True		ENSG00000122512	ENSG00000122512	HGNC:9122													
PTCH1	gene	PTCH1	Expert Review Green;SA Pathology	Medulloblastoma		Cancer Predisposition	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Medulloblastoma, MONDO:0007959;Basal cell nevus syndrome 1, MONDO:0958174;Basal cell nevus syndrome 1, MIM#109400			Medulloblastoma;HP:0002885			False	3	100;0;0	1.1	True		ENSG00000185920	ENSG00000185920	HGNC:9585													
SUFU	gene	SUFU	Expert Review Green;SA Pathology	Medulloblastoma		Cancer Predisposition	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Medulloblastoma, MONDO:0007959;Basal cell nevus syndrome 2, MONDO:0958189;Basal cell nevus syndrome 2, MIM#620343;Meningioma, familial, susceptibility to, MIM#607174;Medulloblastoma predisposition syndrome, MIM#155255			Medulloblastoma;HP:0002885			False	3	100;0;0	1.1	True		ENSG00000107882	ENSG00000107882	HGNC:16466													
TP53	gene	TP53	Expert Review Green;SA Pathology	Medulloblastoma		Cancer Predisposition	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Medulloblastoma, MONDO:0007959;Li-Fraumeni syndrome, MONDO:0018875;Li-Fraumeni syndrome, MIM#151623			Medulloblastoma;HP:0002885			False	3	100;0;0	1.1	True		ENSG00000141510	ENSG00000141510	HGNC:11998