1. Panels
  2. Cardiomyopathy_Paediatric
  3. TNNT2
Genes in panel
Prev Next
STRs in panel
Prev Next
Regions in panel
Prev Next

Cardiomyopathy_Paediatric

Gene: TNNT2

Green List (high evidence)
TNNT2 (troponin T2, cardiac type)
EnsemblGeneIds (GRCh38): ENSG00000118194
EnsemblGeneIds (GRCh37): ENSG00000118194
OMIM: 191045, Gene2Phenotype
TNNT2 is in 9 panels

1 review

Ivan Macciocca (Victorian Clinical Genetics Services)

Green List (high evidence)

DEFINITIVE by ClinGen HCM working group PMID: 30681346
Created: 19 Jun 2020, 2:36 p.m. | Last Modified: 19 Jun 2020, 2:36 p.m.
Panel Version: 0.28

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Phenotypes
HCM; LVNC; RCM; DCM

Publications

Created: 19 Jun 2020, 2:36 p.m.
Last Modified: 19 Jun 2020, 2:36 p.m.
Panel version: Imported from Hypertrophic cardiomyopathy_HCM panel version 0.28

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Green
  • London South GLH
  • South West GLH
  • NHS GMS
Phenotypes
  • Cardiomyopathy, dilated, 1D
  • Cardiomyopathy, familial hypertrophic, 2
  • Hypertrophic cardiomyopathy
  • Left ventricular noncompaction 6,
OMIM
191045
Clinvar variants
Variants in TNNT2
Penetrance
None
Panels with this gene

History Filter Activity

28 Jul 2020, Gel status: 3

Created, Added New Source, Set mode of inheritance, Set Phenotypes

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

gene: TNNT2 was added gene: TNNT2 was added to Cardiomyopathy_Paediatric. Sources: NHS GMS,South West GLH,London South GLH,Expert Review Green Mode of inheritance for gene: TNNT2 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Phenotypes for gene: TNNT2 were set to Cardiomyopathy, dilated, 1D; Cardiomyopathy, familial hypertrophic, 2; Hypertrophic cardiomyopathy; Left ventricular noncompaction 6,