1. Panels
  2. Primary Ovarian Insufficiency_Premature Ovarian Failure
  3. STAG3
STRs in panel
Prev Next
Regions in panel
Prev Next

Primary Ovarian Insufficiency_Premature Ovarian Failure

Gene: STAG3

Green List (high evidence)
STAG3 (stromal antigen 3)
EnsemblGeneIds (GRCh38): ENSG00000066923
EnsemblGeneIds (GRCh37): ENSG00000066923
OMIM: 608489, Gene2Phenotype
STAG3 is in 2 panels

1 review

Bryony Thompson (Royal Melbourne Hospital)

Green List (high evidence)

At least four unrelated families with ovarian failure and a supporting null mouse model.
Created: 17 Jun 2020, 11:43 p.m. | Last Modified: 17 Jun 2020, 11:43 p.m.
Panel Version: 0.4

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Phenotypes
Premature ovarian failure 8 MIM#615723

Publications

Created: 17 Jun 2020, 11:43 p.m.
Last Modified: 17 Jun 2020, 11:43 p.m.
Panel version: 0.4

Details

Mode of Inheritance
BIALLELIC, autosomal or pseudoautosomal
Sources
  • Genetic Health QLD
  • Expert Review Green
  • NHS GMS
Phenotypes
  • Premature ovarian failure 8 MIM#615723
OMIM
608489
Clinvar variants
Variants in STAG3
Penetrance
None
Publications
Panels with this gene

History Filter Activity

22 Dec 2021, Gel status: 3

Set Phenotypes

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Phenotypes for gene: STAG3 were changed from Premature ovarian failure 8 MIM#615723; Spermatogenic failure 61, MIM# 619672 to Premature ovarian failure 8 MIM#615723

22 Dec 2021, Gel status: 3

Set publications

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Publications for gene: STAG3 were set to 24597867; 26059840; 31803224; 31363903; 31125047; 31682730; 32634216

22 Dec 2021, Gel status: 3

Set Phenotypes

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Phenotypes for gene: STAG3 were changed from Premature ovarian failure 8 MIM#615723 to Premature ovarian failure 8 MIM#615723; Spermatogenic failure 61, MIM# 619672

22 Dec 2021, Gel status: 3

Set publications

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Publications for gene: STAG3 were set to 24597867; 26059840; 31803224; 31363903

22 Dec 2021, Gel status: 3

Set mode of inheritance

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Mode of inheritance for gene: STAG3 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal

11 Dec 2020, Gel status: 3

Added New Source, Set mode of inheritance

Bryony Thompson (Royal Melbourne Hospital)

Source Genetic Health QLD was added to STAG3. Mode of inheritance for gene STAG3 was changed from BIALLELIC, autosomal or pseudoautosomal to Unknown

17 Jun 2020, Gel status: 3

Entity classified by Genomics England curator

Bryony Thompson (Royal Melbourne Hospital)

Gene: stag3 has been classified as Green List (High Evidence).

17 Jun 2020, Gel status: 3

Set Phenotypes

Bryony Thompson (Royal Melbourne Hospital)

Phenotypes for gene: STAG3 were changed from to Premature ovarian failure 8 MIM#615723

17 Jun 2020, Gel status: 3

Set publications

Bryony Thompson (Royal Melbourne Hospital)

Publications for gene: STAG3 were set to

17 Jun 2020, Gel status: 3

Created, Added New Source, Set mode of inheritance

Bryony Thompson (Royal Melbourne Hospital)

gene: STAG3 was added gene: STAG3 was added to Amenorrhoea. Sources: NHS GMS,Expert Review Green Mode of inheritance for gene: STAG3 was set to BIALLELIC, autosomal or pseudoautosomal