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  2. Primary Ovarian Insufficiency_Premature Ovarian Failure
  3. SGO2
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Primary Ovarian Insufficiency_Premature Ovarian Failure

Gene: SGO2

Red List (low evidence)
SGO2 (shugoshin 2)
EnsemblGeneIds (GRCh38): ENSG00000163535
EnsemblGeneIds (GRCh37): ENSG00000163535
OMIM: 612425, Gene2Phenotype
SGO2 is in 2 panels

1 review

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Red List (low evidence)

Single affected individual reported, though deafness was thought to be explained by a CLDN14 variant. Protein is known to be involved in meiosis.
Created: 11 Dec 2020, 4:53 a.m. | Last Modified: 11 Dec 2020, 4:53 a.m.
Panel Version: 0.127

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Phenotypes
Perrault syndrome

Publications

Created: 11 Dec 2020, 4:53 a.m.
Last Modified: 11 Dec 2020, 4:53 a.m.
Panel version: 0.127

Details

Mode of Inheritance
BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Red
  • Genetic Health QLD
Phenotypes
  • Perrault syndrome
OMIM
612425
Clinvar variants
Variants in SGO2
Penetrance
None
Publications
Panels with this gene

History Filter Activity

11 Dec 2020, Gel status: 1

Entity classified by Genomics England curator

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Gene: sgo2 has been classified as Red List (Low Evidence).

11 Dec 2020, Gel status: 1

Set Phenotypes

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Phenotypes for gene: SGO2 were changed from to Perrault syndrome

11 Dec 2020, Gel status: 1

Set publications

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Publications for gene: SGO2 were set to

11 Dec 2020, Gel status: 1

Set mode of inheritance

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Mode of inheritance for gene: SGO2 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal

11 Dec 2020, Gel status: 1

Created, Added New Source, Set mode of inheritance

Bryony Thompson (Royal Melbourne Hospital)

gene: SGO2 was added gene: SGO2 was added to Primary Ovarian Insufficiency_Premature Ovarian Failure. Sources: Genetic Health QLD Mode of inheritance for gene: SGO2 was set to Unknown