Primary Ovarian Insufficiency_Premature Ovarian Failure

Gene: NOG

Red List (low evidence)

NOG (noggin)
EnsemblGeneIds (GRCh38): ENSG00000183691
EnsemblGeneIds (GRCh37): ENSG00000183691
OMIM: 602991, Gene2Phenotype
NOG is in 7 panels

1 review

Bryony Thompson (Royal Melbourne Hospital)

Red List (low evidence)

Premature ovarian failure is not a prominent or common feature of proximal symphalangism. Only 2 cases have been reported with POI.
Created: 11 Dec 2020, 6:02 a.m. | Last Modified: 11 Dec 2020, 6:02 a.m.
Panel Version: 0.153

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Phenotypes
Symphalangism, proximal, 1A MIM#185800

Publications

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Red
  • Genetic Health QLD
Phenotypes
  • Symphalangism, proximal, 1A MIM#185800
OMIM
602991
Clinvar variants
Variants in NOG
Penetrance
None
Publications
Panels with this gene

History Filter Activity

11 Dec 2020, Gel status: 1

Entity classified by Genomics England curator

Bryony Thompson (Royal Melbourne Hospital)

Gene: nog has been classified as Red List (Low Evidence).

11 Dec 2020, Gel status: 1

Set Phenotypes

Bryony Thompson (Royal Melbourne Hospital)

Phenotypes for gene: NOG were changed from to Symphalangism, proximal, 1A MIM#185800

11 Dec 2020, Gel status: 1

Set publications

Bryony Thompson (Royal Melbourne Hospital)

Publications for gene: NOG were set to

11 Dec 2020, Gel status: 1

Set mode of inheritance

Bryony Thompson (Royal Melbourne Hospital)

Mode of inheritance for gene: NOG was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

11 Dec 2020, Gel status: 1

Created, Added New Source, Set mode of inheritance

Bryony Thompson (Royal Melbourne Hospital)

gene: NOG was added gene: NOG was added to Primary Ovarian Insufficiency_Premature Ovarian Failure. Sources: Genetic Health QLD Mode of inheritance for gene: NOG was set to Unknown