Primary Ovarian Insufficiency_Premature Ovarian Failure
Gene: HS6ST1
Postulated to exert an effect under a polygenic susceptibility, rather than Mendelian, model.Created: 18 Jul 2020, 7:41 a.m. | Last Modified: 18 Jul 2020, 7:41 a.m.
Panel Version: 0.3387
Mode of inheritance
Other
Phenotypes
{Hypogonadotropic hypogonadism 15 with or without anosmia} 614880
Publications
Inconclusive evidence of a monogenic association with disease. There are a limited number of reports linking HS6ST1 to hypotropic hypogonadism, however most of the variants are either co-inherited with variants from other candidate genes or common in gnomAD.Created: 6 Jul 2020, 5:07 a.m. | Last Modified: 6 Jul 2020, 5:07 a.m.
Panel Version: 0.19
Mode of inheritance
Unknown
Gene: hs6st1 has been classified as Red List (Low Evidence).
Gene: hs6st1 has been classified as Red List (Low Evidence).
gene: HS6ST1 was added gene: HS6ST1 was added to Amenorrhoea. Sources: Expert Review Green,Royal Melbourne Hospital Mode of inheritance for gene: HS6ST1 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Phenotypes for gene: HS6ST1 were set to {Hypogonadotropic hypogonadism 15 with or without anosmia} 614880