1. Panels
  2. Ectodermal Dysplasia
  3. WNT10A
STRs in panel
Prev Next
Regions in panel
Prev Next

Ectodermal Dysplasia

Gene: WNT10A

Green List (high evidence)
WNT10A (Wnt family member 10A)
EnsemblGeneIds (GRCh38): ENSG00000135925
EnsemblGeneIds (GRCh37): ENSG00000135925
OMIM: 606268, Gene2Phenotype
WNT10A is in 6 panels

1 review

Elena Savva (Victorian Clinical Genetics Services)

Green List (high evidence)

Appears to be fully penetrant in PTC homozygotes, however missense compound heterozygotes and heterozygote carriers may be unaffected, or display only some phenotypic manifestation
Created: 7 Feb 2020, 4:50 a.m. | Last Modified: 7 Feb 2020, 4:50 a.m.
Panel Version: 0.1285

Mode of inheritance
BOTH monoallelic and biallelic, autosomal or pseudoautosomal

Phenotypes
Odontoonychodermal dysplasia; Schopf-Schulz-Passarge syndrome; Tooth agenesis, selective, 4

Publications

Variants in this GENE are reported as part of current diagnostic practice

Created: 7 Feb 2020, 4:50 a.m.
Last Modified: 7 Feb 2020, 4:50 a.m.
Panel version: Imported from Mendeliome panel version 0.1285

Details

Mode of Inheritance
BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Royal Melbourne Hospital
Phenotypes
  • Odontoonychodermal dysplasia, Tooth agenesis, selective, Schopf-Schulz-Passarge syndrome
OMIM
606268
Clinvar variants
Variants in WNT10A
Penetrance
None
Panels with this gene

History Filter Activity

14 Jan 2020, Gel status: 3

Created, Added New Source, Set mode of inheritance, Set Phenotypes

Bryony Thompson (Royal Melbourne Hospital)

gene: WNT10A was added gene: WNT10A was added to Ectodermal Dysplasia_RMH. Sources: Royal Melbourne Hospital,Expert Review Green Mode of inheritance for gene: WNT10A was set to BOTH monoallelic and biallelic, autosomal or pseudoautosomal Phenotypes for gene: WNT10A were set to Odontoonychodermal dysplasia, Tooth agenesis, selective, Schopf-Schulz-Passarge syndrome