Ataxia - adult onset
Gene: ANO10

ANO10 (anoctamin 10)
EnsemblGeneIds (GRCh38): ENSG00000160746
EnsemblGeneIds (GRCh37): ENSG00000160746
OMIM: 613726, Gene2Phenotype
ANO10 is in 6 panels

2 reviews

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Green List (high evidence)

At least 5 unrelated families reported.
Created: 30 Apr 2022, 7:16 a.m. | Last Modified: 30 Apr 2022, 7:16 a.m.

Panel Version: 0.13464

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Phenotypes
Spinocerebellar ataxia, autosomal recessive 10, MIM#613728

Publications

Created: 30 Apr 2022, 7:16 a.m.
Last Modified: 30 Apr 2022, 7:16 a.m.
Panel version: Imported from Mendeliome panel version 0.13464

Bryony Thompson (Royal Melbourne Hospital)

Green List (high evidence)

Onset of ataxia is in adolescence or adulthood.
Sources: Expert list
Created: 16 Apr 2020, 10:23 p.m.

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Phenotypes
Spinocerebellar ataxia, autosomal recessive 10 MIM#613728

Created: 16 Apr 2020, 10:23 p.m.

Panel version: Imported from Mendeliome panel version Imported from Ataxia - paediatric panel version 0.79

Details

Mode of Inheritance

BIALLELIC, autosomal or pseudoautosomal

Sources

Expert list
Royal Melbourne Hospital
Expert Review Green
Victorian Clinical Genetics Services

Phenotypes

Spinocerebellar ataxia autosomal recessive type 10, 613728
Spinocerebellar ataxia, autosomal recessive 10

OMIM

613726

Clinvar variants

Variants in ANO10

Penetrance

None

Panels with this gene

History Filter Activity

19 Dec 2019, Gel status: 3

Created, Added New Source, Set mode of inheritance, Set Phenotypes

Bryony Thompson (Royal Melbourne Hospital)

gene: ANO10 was added gene: ANO10 was added to Ataxia - adult onset_RMH. Sources: Expert Review Green,Royal Melbourne Hospital Mode of inheritance for gene: ANO10 was set to BIALLELIC, autosomal or pseudoautosomal Phenotypes for gene: ANO10 were set to Spinocerebellar ataxia autosomal recessive type 10, 613728; Spinocerebellar ataxia, autosomal recessive 10

Ataxia - adult onset Gene: ANO10