1. Panels
  2. Early-onset Parkinson disease
  3. KIF5A
Regions in panel
Prev Next

Early-onset Parkinson disease

Gene: KIF5A

Amber List (moderate evidence)
KIF5A (kinesin family member 5A)
EnsemblGeneIds (GRCh38): ENSG00000155980
EnsemblGeneIds (GRCh37): ENSG00000155980
OMIM: 602821, Gene2Phenotype
KIF5A is in 12 panels

1 review

Bryony Thompson (Royal Melbourne Hospital)

I don't know

Parkinsonism is reported in two families with complicated SPG10.
Created: 26 Mar 2020, 3:29 a.m. | Last Modified: 26 Mar 2020, 3:29 a.m.
Panel Version: 0.19

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Phenotypes
Spastic paraplegia 10, autosomal dominant MIM#604187

Publications

Created: 26 Mar 2020, 3:29 a.m.
Last Modified: 26 Mar 2020, 3:29 a.m.
Panel version: 0.19

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Amber
  • Melbourne Genomics Health Alliance Complex Neurology Flagship
  • Victorian Clinical Genetics Services
Phenotypes
  • Spastic paraplegia 10, autosomal dominant MIM#604187
OMIM
602821
Clinvar variants
Variants in KIF5A
Penetrance
None
Publications
Panels with this gene

History Filter Activity

20 Apr 2024, Gel status: 2

Set Phenotypes

Bryony Thompson (Royal Melbourne Hospital)

Phenotypes for gene: KIF5A were changed from to Spastic paraplegia 10, autosomal dominant MIM#604187

20 Apr 2024, Gel status: 2

Set publications

Bryony Thompson (Royal Melbourne Hospital)

Publications for gene: KIF5A were set to

20 Apr 2024, Gel status: 2

Set mode of inheritance

Bryony Thompson (Royal Melbourne Hospital)

Mode of inheritance for gene: KIF5A was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

26 Mar 2020, Gel status: 2

Entity classified by Genomics England curator

Bryony Thompson (Royal Melbourne Hospital)

Gene: kif5a has been classified as Amber List (Moderate Evidence).

26 Mar 2020, Gel status: 2

Entity classified by Genomics England curator

Bryony Thompson (Royal Melbourne Hospital)

Gene: kif5a has been classified as Amber List (Moderate Evidence).

17 Nov 2019, Gel status: 3

Created, Added New Source, Set mode of inheritance

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

gene: KIF5A was added gene: KIF5A was added to Early onset Parkinson disease_MelbourneGenomics_VCGS. Sources: Expert Review Green,Victorian Clinical Genetics Services,Melbourne Genomics Health Alliance Complex Neurology Flagship Mode of inheritance for gene: KIF5A was set to Unknown