Early-onset Parkinson disease
Gene: FTL

FTL (ferritin light chain)
EnsemblGeneIds (GRCh38): ENSG00000087086
EnsemblGeneIds (GRCh37): ENSG00000087086
OMIM: 134790, Gene2Phenotype
FTL is in 12 panels

2 reviews

Bryony Thompson (Royal Melbourne Hospital)

Comment on list classification: Parkinsonism can be a presenting feature of the condition
Created: 22 Feb 2024, 5:18 a.m. | Last Modified: 22 Feb 2024, 5:18 a.m.

Panel Version: 0.291

Comment on list classification: Parkinsonism can be a presenting feature of the condition
Created: 22 Feb 2024, 5:17 a.m. | Last Modified: 22 Feb 2024, 5:17 a.m.

Panel Version: 0.291

Created: 22 Feb 2024, 5:17 a.m.
Last Modified: 22 Feb 2024, 5:17 a.m.
Panel version: 0.291

Kaitlyn Dianna Weldon (University of Melbourne)

Green List (high evidence)

This is a well-established Parkinson disease gene
Created: 25 Aug 2023, 1:39 a.m. | Last Modified: 25 Aug 2023, 1:39 a.m.

Panel Version: 0.243

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Phenotypes
neuroferritinopathy MONDO:0011638

Publications

Created: 25 Aug 2023, 1:39 a.m.
Last Modified: 25 Aug 2023, 1:39 a.m.
Panel version: 0.243

Details

Mode of Inheritance

MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Sources

Expert Review Green
Melbourne Genomics Health Alliance Complex Neurology Flagship
Victorian Clinical Genetics Services

OMIM

134790

Clinvar variants

Variants in FTL

Penetrance

None

Publications

Panels with this gene