Entity Name	Entity type	Gene Symbol	Sources(; separated)	Level4	Level3	Level2	Model_Of_Inheritance	Phenotypes	Omim	Orphanet	HPO	Publications	Description	Flagged	GEL_Status	UserRatings_Green_amber_red	version	ready	Mode of pathogenicity	EnsemblId(GRch37)	EnsemblId(GRch38)	HGNC	Position Chromosome	Position GRCh37 Start	Position GRCh37 End	Position GRCh38 Start	Position GRCh38 End	STR Repeated Sequence	STR Normal Repeats	STR Pathogenic Repeats	Region Haploinsufficiency Score	Region Triplosensitivity Score	Region Required Overlap Percentage	Region Variant Type	Region Verbose Name
ALPL	gene	ALPL	Expert Review Red;Literature	Early-onset Parkinson disease		Neurology and neurodevelopmental disorders	BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal	Hypophosphatasia, adult, MIM# 146300;Osteomalacia;Parkinsonism			Abnormality of extrapyramidal motor function;HP:0002071	PMID: 32956941		False	1	50;0;50	2.10	True		ENSG00000162551	ENSG00000162551	HGNC:438													
ANG	gene	ANG	Expert Review Red;Literature	Early-onset Parkinson disease		Neurology and neurodevelopmental disorders	Unknown	Parkinson disease MONDO:0005180			Abnormality of extrapyramidal motor function;HP:0002071	33875291;25386690		False	1	0;0;100	2.10	True		ENSG00000214274	ENSG00000214274	HGNC:483													
DCAF17	gene	DCAF17	Expert Review Red;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Early-onset Parkinson disease		Neurology and neurodevelopmental disorders	Unknown				Abnormality of extrapyramidal motor function;HP:0002071			False	1	0;0;100	2.10	True		ENSG00000115827	ENSG00000115827	HGNC:25784													
DNAJC13	gene	DNAJC13	Expert list;Expert Review Red	Early-onset Parkinson disease		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted				Abnormality of extrapyramidal motor function;HP:0002071	30788857;24218364;29309590;31082451;29887357;27270108		False	1	0;100;0	2.10	True		ENSG00000138246	ENSG00000138246	HGNC:30343													
FUS	gene	FUS	Expert Review Red;Literature	Early-onset Parkinson disease		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	"tremor, hereditary essential, 4	MONDO:0013888"			Abnormality of extrapyramidal motor function;HP:0002071	22863194;23834483;23825177;38626532		False	1	0;0;100	2.10	True		ENSG00000089280	ENSG00000089280	HGNC:4010													
GIGYF2	gene	GIGYF2	Expert Review Red;Literature	Early-onset Parkinson disease		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	{Parkinson disease 11} , OMIM # 607688			Abnormality of extrapyramidal motor function;HP:0002071	18358451;33239198;25279164;20060621;19250854;26152800;19449032		False	1	0;50;50	2.10	True		ENSG00000204120	ENSG00000204120	HGNC:11960													
HEXA	gene	HEXA	Expert Review Red;Literature	Early-onset Parkinson disease		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	GM2 Gangliosidosis;Tay-Sachs disease;Parkinsonism;OMIM 272800			Abnormality of extrapyramidal motor function;HP:0002071	PMID: 33069254		False	1	50;0;50	2.10	True		ENSG00000213614	ENSG00000213614	HGNC:4878													
OPA3	gene	OPA3	Expert Review Red;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Early-onset Parkinson disease		Neurology and neurodevelopmental disorders	Unknown				Abnormality of extrapyramidal motor function;HP:0002071			False	1	0;0;100	2.10	True		ENSG00000125741	ENSG00000125741	HGNC:8142													
PODXL	gene	PODXL	Literature	Early-onset Parkinson disease		Neurology and neurodevelopmental disorders	Unknown	juvenile-onset Parkinson disease			Abnormality of extrapyramidal motor function;HP:0002071	26864383;20706633		False	1	0;100;0	2.10	False		ENSG00000128567	ENSG00000128567	HGNC:9171													
PSEN2	gene	PSEN2	Expert Review Red;Other	Early-onset Parkinson disease		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Parkinsonism;Alzheimer disease-4 MIM#606889			Abnormality of extrapyramidal motor function;HP:0002071	22118943;26422362;18427071;29692703		False	1	0;0;100	2.10	True		ENSG00000143801	ENSG00000143801	HGNC:9509													
RIC3	gene	RIC3	Expert Review Red;Other	Early-onset Parkinson disease		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Parkinson disease			Abnormality of extrapyramidal motor function;HP:0002071	27055476;28153381;28606768;32794657		False	1	0;0;100	2.10	True		ENSG00000166405	ENSG00000166405	HGNC:30338													
TMEM230	gene	TMEM230	Expert list	Early-onset Parkinson disease		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Parkinson disease 21, MIM#616361			Abnormality of extrapyramidal motor function;HP:0002071	30804554;27270108;28115417;28017548;30804555;30804556;31323517		False	1	0;100;0	2.10	False		ENSG00000089063	ENSG00000089063	HGNC:15876													
TUBB4A	gene	TUBB4A	Expert Review Red;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Early-onset Parkinson disease		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted				Abnormality of extrapyramidal motor function;HP:0002071			False	1	0;0;100	2.10	True		ENSG00000104833	ENSG00000104833	HGNC:20774													
WASL	gene	WASL	Expert Review Red;Literature	Early-onset Parkinson disease		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Parkinson's disease, MONDO:0005180, WASL-related			Abnormality of extrapyramidal motor function;HP:0002071	PMID: 33571872		False	1	50;0;50	2.10	True		ENSG00000106299	ENSG00000106299	HGNC:12735