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Intellectual disability syndromic and non-syndromic

Gene: GMNN

Amber List (moderate evidence)

GMNN (geminin, DNA replication inhibitor)
EnsemblGeneIds (GRCh38): ENSG00000112312
EnsemblGeneIds (GRCh37): ENSG00000112312
OMIM: 602842, Gene2Phenotype
GMNN is in 5 panels

1 review

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

I don't know

Two of the three reported individuals had ID.
Sources: Expert list
Created: 6 Feb 2020, 1:24 a.m.

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Phenotypes
Meier-Gorlin syndrome 6, MIM# 616835

Publications

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Amber
  • Expert list
Phenotypes
  • Meier-Gorlin syndrome 6, MIM# 616835
OMIM
602842
Clinvar variants
Variants in GMNN
Penetrance
None
Publications
Panels with this gene

History Filter Activity

6 Feb 2020, Gel status: 2

Entity classified by Genomics England curator

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Gene: gmnn has been classified as Amber List (Moderate Evidence).

6 Feb 2020, Gel status: 2

Entity classified by Genomics England curator

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Gene: gmnn has been classified as Amber List (Moderate Evidence).

6 Feb 2020, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set publications, Set Phenotypes

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

gene: GMNN was added gene: GMNN was added to Intellectual disability syndromic and non-syndromic. Sources: Expert list Mode of inheritance for gene: GMNN was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Publications for gene: GMNN were set to 26637980 Phenotypes for gene: GMNN were set to Meier-Gorlin syndrome 6, MIM# 616835 Review for gene: GMNN was set to AMBER