Entity Name	Entity type	Gene Symbol	Sources(; separated)	Level4	Level3	Level2	Model_Of_Inheritance	Phenotypes	Omim	Orphanet	HPO	Publications	Description	Flagged	GEL_Status	UserRatings_Green_amber_red	version	ready	Mode of pathogenicity	EnsemblId(GRch37)	EnsemblId(GRch38)	HGNC	Position Chromosome	Position GRCh37 Start	Position GRCh37 End	Position GRCh38 Start	Position GRCh38 End	STR Repeated Sequence	STR Normal Repeats	STR Pathogenic Repeats	Region Haploinsufficiency Score	Region Triplosensitivity Score	Region Required Overlap Percentage	Region Variant Type	Region Verbose Name
ANG	gene	ANG	Expert Review Amber;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Motor Neurone Disease		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Amyotrophic Lateral Sclerosis 9 (MONDO: 0012753;MIM#611895)				17886298;16501576;18087731;20301623		False	2	100;0;0	1.27	True		ENSG00000214274	ENSG00000214274	HGNC:483													
CCNF	gene	CCNF	Expert list;Expert Review Amber	Motor Neurone Disease		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Frontotemporal dementia and/or amyotrophic lateral sclerosis 5, MIM# 619141				29102476;31577344;27080313;28105640;31445393;28852778		False	2	0;100;0	1.27	True		ENSG00000162063	ENSG00000162063	HGNC:1591													
CYLD	gene	CYLD	Expert Review Amber;Literature;Victorian Clinical Genetics Services	Motor Neurone Disease		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Frontotemporal dementia and/or amytrophic lateral sclerosis 8, MIM# 619132				32666117;32666099;32185393		False	2	25;50;25	1.27	True	Other	ENSG00000083799	ENSG00000083799	HGNC:2584													
DNAJC7	gene	DNAJC7	Expert Review Amber;Literature	Motor Neurone Disease		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	amyotrophic lateral sclerosis				31768050		False	2	33;67;0	1.27	True		ENSG00000168259	ENSG00000168259	HGNC:12392													
ERBB4	gene	ERBB4	Expert list;Expert Review Amber;Victorian Clinical Genetics Services	Motor Neurone Disease		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Amyotrophic lateral sclerosis 19 MIM#615515				24119685;28889094		False	2	100;0;0	1.27	True		ENSG00000178568	ENSG00000178568	HGNC:3432													
FIG4	gene	FIG4	Expert Review Amber;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Motor Neurone Disease		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Amyotrophic Lateral Sclerosis Type 11 (MONDO: 0012945;MIM#612577)						False	2	100;0;0	1.27	True		ENSG00000112367	ENSG00000112367	HGNC:16873													
GLT8D1	gene	GLT8D1	Expert list;Expert Review Amber	Motor Neurone Disease		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Amyotrophic lateral sclerosis				30811981		False	2	50;50;0	1.27	True		ENSG00000016864	ENSG00000016864	HGNC:24870													
HNRNPA2B1	gene	HNRNPA2B1	ClinGen;Expert Review Amber	Motor Neurone Disease		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	amyotrophic lateral sclerosis MONDO:0004976				25299611		False	2	0;0;100	1.27	True		ENSG00000122566	ENSG00000122566	HGNC:5033													
LGALSL	gene	LGALSL	ClinGen;Expert Review Amber	Motor Neurone Disease		Neurology and neurodevelopmental disorders	Unknown	amyotrophic lateral sclerosis MONDO:0004976				30940688		False	2	0;100;0	1.27	True		ENSG00000119862	ENSG00000119862	HGNC:25012													
PRPH	gene	PRPH	Expert list;Expert Review Amber;Melbourne Genomics Health Alliance Complex Neurology Flagship;Victorian Clinical Genetics Services	Motor Neurone Disease		Neurology and neurodevelopmental disorders	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	{Amyotrophic lateral sclerosis, susceptibility to}, 105400				20363051;15322088;15446584		False	2	0;100;0	1.27	True		ENSG00000135406	ENSG00000135406	HGNC:9461													
RNF13	gene	RNF13	Expert Review Amber;Expert Review Green;Literature	Motor Neurone Disease		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Amyotrophic lateral sclerosis				PMID: 35879052		False	2	50;50;0	1.27	True		ENSG00000082996	ENSG00000082996	HGNC:10057													
SQSTM1	gene	SQSTM1	Expert Review Amber;Melbourne Genomics Health Alliance Complex Neurology Flagship;Royal Melbourne Hospital;Victorian Clinical Genetics Services	Motor Neurone Disease		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	"Frontotemporal dementia and/or amyotrophic lateral sclerosis 3	MONDO:0014640"						False	2	100;0;0	1.27	True		ENSG00000161011	ENSG00000161011	HGNC:11280													
SS18L1	gene	SS18L1	Expert list;Expert Review Amber	Motor Neurone Disease		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	amyotrophic lateral sclerosis (MONDO:0004976)				25888396;24360741;23708140;30976389		False	2	50;50;0	1.27	True		ENSG00000184402	ENSG00000184402	HGNC:15592													
TAF15	gene	TAF15	Expert list;Expert Review Amber	Motor Neurone Disease		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Amyotrophic lateral sclerosis				21438137;22065782;27810362;28889094		False	2	0;100;0	1.27	True		ENSG00000172660	ENSG00000270647	HGNC:11547													
TIA1	gene	TIA1	Expert list;Expert Review Amber	Motor Neurone Disease		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	"Amyotrophic lateral sclerosis 26 with or without frontotemporal dementia	619133"				29235362;29886022;29773329;29699721;29216908;24659297;29457785;28817800		False	2	0;100;0	1.27	True		ENSG00000116001	ENSG00000116001	HGNC:11802													
UBQLN4	gene	UBQLN4	Expert list;Expert Review Amber	Motor Neurone Disease		Neurology and neurodevelopmental disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Amyotrophic lateral sclerosis				28463112;30804504		False	2	0;100;0	1.27	False		ENSG00000160803	ENSG00000160803	HGNC:1237													
VRK1	gene	VRK1	Expert Review Amber;Melbourne Genomics Health Alliance Complex Neurology Flagship;Royal Melbourne Hospital;Victorian Clinical Genetics Services	Motor Neurone Disease		Neurology and neurodevelopmental disorders	BIALLELIC, autosomal or pseudoautosomal	Adult-onset spinal muscular atrophy without pontocerebellar hypoplasia;Distal hereditary motor neuropathy;dHMN/dSMA				31560180;32242460;31178479;31837156;30847374;34169149;26583493		False	2	0;50;50	1.27	True		ENSG00000100749	ENSG00000100749	HGNC:12718