Early-onset Dementia
Gene: FUS

FUS (FUS RNA binding protein)
EnsemblGeneIds (GRCh38): ENSG00000089280
EnsemblGeneIds (GRCh37): ENSG00000089280
OMIM: 137070, Gene2Phenotype
FUS is in 7 panels

1 review

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Green List (high evidence)

Predominantly associated with ALS phenotype, but dementia reported.
Created: 25 Sep 2020, 1:56 a.m. | Last Modified: 25 Sep 2020, 1:56 a.m.

Panel Version: 0.100

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Phenotypes
Amyotrophic lateral sclerosis 6, with or without frontotemporal dementia, MIM# 608030

Publications

Created: 25 Sep 2020, 1:56 a.m.
Last Modified: 25 Sep 2020, 1:56 a.m.
Panel version: 0.100

Details

Mode of Inheritance

MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Sources

Expert Review Green
Melbourne Genomics Health Alliance Complex Neurology Flagship
Victorian Clinical Genetics Services

Phenotypes

Amyotrophic lateral sclerosis 6, with or without frontotemporal dementia, MIM# 608030

OMIM

137070

Clinvar variants

Variants in FUS

Penetrance

None

Publications

Panels with this gene