Early-onset Dementia
Gene: ANG
ANG (angiogenin)
EnsemblGeneIds (GRCh38): ENSG00000214274
EnsemblGeneIds (GRCh37): ENSG00000214274
OMIM: 105850, Gene2Phenotype
ANG is in 4 panels
EnsemblGeneIds (GRCh38): ENSG00000214274
EnsemblGeneIds (GRCh37): ENSG00000214274
OMIM: 105850, Gene2Phenotype
ANG is in 4 panels
1 review
Bryony Thompson (Royal Melbourne Hospital)
Comment on list classification: Not a prominent ALS-FTD phenotypeCreated: 6 Feb 2020, 8:54 a.m. | Last Modified: 6 Feb 2020, 8:54 a.m.
Panel Version: 0.18
Only one report of dementia in one case in a large familial ALS pedigree. Dementia or cognitive decline is not a prominent feature of the condition.Created: 5 Feb 2020, 6:27 a.m. | Last Modified: 5 Feb 2020, 6:27 a.m.
Panel Version: 0.1
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
Amyotrophic lateral sclerosis 9 MIM#611895
Publications
Details
- Mode of Inheritance
- Unknown
- Sources
-
- Expert Review Red
- Melbourne Genomics Health Alliance Complex Neurology Flagship
- Victorian Clinical Genetics Services
- OMIM
- 105850
- Clinvar variants
- Variants in ANG
- Penetrance
- None
- Panels with this gene
History Filter Activity
21 Aug 2023, Gel status: 1
Entity classified by Genomics England curator
Bryony Thompson (Royal Melbourne Hospital)Gene: ang has been classified as Red List (Low Evidence).
6 Feb 2020, Gel status: 1
Entity classified by Genomics England curator
Bryony Thompson (Royal Melbourne Hospital)Gene: ang has been classified as Red List (Low Evidence).
17 Nov 2019, Gel status: 3
Created, Added New Source, Set mode of inheritance
Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)gene: ANG was added gene: ANG was added to Early-onset Dementia_MGHA_VCGS. Sources: Expert Review Green,Victorian Clinical Genetics Services,Melbourne Genomics Health Alliance Complex Neurology Flagship Mode of inheritance for gene: ANG was set to Unknown