Susceptibility to Viral Infections
Gene: IFNAR1
Seven children from five unrelated kindredsCreated: 11 Jul 2022, 4:10 a.m. | Last Modified: 11 Jul 2022, 4:10 a.m.
Panel Version: 0.83
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Severe Viral disease
Publications
Two unrelated individuals reported with bi-allelic LoF variants, some functional data.
Sources: Expert listCreated: 5 Apr 2020, 7:45 a.m.
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Severe disease caused by Yellow Fever vaccine and Measles vaccine
Publications
Phenotypes for gene: IFNAR1 were changed from Severe disease caused by Yellow Fever vaccine and Measles vaccine to Immunodeficiency 106, susceptibility to viral infections, MIM# 619935; Severe disease caused by Yellow Fever vaccine and Measles vaccine
Gene: ifnar1 has been classified as Green List (High Evidence).
Gene: ifnar1 has been classified as Amber List (Moderate Evidence).
Gene: ifnar1 has been classified as Amber List (Moderate Evidence).
gene: IFNAR1 was added gene: IFNAR1 was added to Susceptibility to Viral Infections. Sources: Expert list Mode of inheritance for gene: IFNAR1 was set to BIALLELIC, autosomal or pseudoautosomal Publications for gene: IFNAR1 were set to 31270247 Phenotypes for gene: IFNAR1 were set to Severe disease caused by Yellow Fever vaccine and Measles vaccine Review for gene: IFNAR1 was set to AMBER