Entity Name	Entity type	Gene Symbol	Sources(; separated)	Level4	Level3	Level2	Model_Of_Inheritance	Phenotypes	Omim	Orphanet	HPO	Publications	Description	Flagged	GEL_Status	UserRatings_Green_amber_red	version	ready	Mode of pathogenicity	EnsemblId(GRch37)	EnsemblId(GRch38)	HGNC	Position Chromosome	Position GRCh37 Start	Position GRCh37 End	Position GRCh38 Start	Position GRCh38 End	STR Repeated Sequence	STR Normal Repeats	STR Pathogenic Repeats	Region Haploinsufficiency Score	Region Triplosensitivity Score	Region Required Overlap Percentage	Region Variant Type	Region Verbose Name
CD28	gene	CD28	Expert Review Amber;Literature	Susceptibility to Viral Infections		Immunological disorders	BIALLELIC, autosomal or pseudoautosomal	Immunodeficiency-123 with HPV-related verrucosis (IMD123), MIM#620901;isolated susceptibility to cutaneous  - and  -HPVs			Recurrent viral infections;HP:0004429; Severe viral infection;HP:0031691	PMID: 34214472		False	2	0;50;50	0.131	True		ENSG00000178562	ENSG00000178562	HGNC:1653													
FCGR3A	gene	FCGR3A	Expert Review Amber;Melbourne Genomics Health Alliance Immunology Flagship;Victorian Clinical Genetics Services	Susceptibility to Viral Infections		Immunological disorders	BIALLELIC, autosomal or pseudoautosomal	Immunodeficiency 20, MIM# 615707			Recurrent viral infections;HP:0004429; Severe viral infection;HP:0031691	8874200;23006327;8608639		False	2	0;100;0	0.131	True		ENSG00000203747	ENSG00000203747	HGNC:3619													
IKBKE	gene	IKBKE	Expert Review Amber;Literature	Susceptibility to Viral Infections		Immunological disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Encephalitis, acute, infection-induced, susceptibility to, MONDO:0800174, IKBKE-related			Recurrent viral infections;HP:0004429; Severe viral infection;HP:0031691	PMID: 37937644		False	2	0;100;0	0.131	True		-	-	HGNC:14552													
IL27RA	gene	IL27RA	Expert Review Amber;Literature	Susceptibility to Viral Infections		Immunological disorders	BIALLELIC, autosomal or pseudoautosomal	Epstein-Barr virus infection MONDO:0005111  , IL27RA-related			Recurrent viral infections;HP:0004429; Severe viral infection;HP:0031691	38509369		False	2	0;100;0	0.131	True		ENSG00000104998	ENSG00000104998	HGNC:17290													
IRF3	gene	IRF3	Expert list;Expert Review Amber	Susceptibility to Viral Infections		Immunological disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	"{Encephalopathy, acute, infection-induced (herpes-specific), susceptibility to, 7}, MIM#	616532"			Recurrent viral infections;HP:0004429; Severe viral infection;HP:0031691	26216125;20660188;26513235		False	2	0;100;0	0.131	True		ENSG00000126456	ENSG00000126456	HGNC:6118													
IRF9	gene	IRF9	Expert list;Expert Review Amber	Susceptibility to Viral Infections		Immunological disorders	BIALLELIC, autosomal or pseudoautosomal	"Immunodeficiency 65, susceptibility to viral infections	618648"			Recurrent viral infections;HP:0004429; Severe viral infection;HP:0031691	30826365;30143481		False	2	0;100;0	0.131	True		ENSG00000213928	ENSG00000213928	HGNC:6131													
MCM10	gene	MCM10	Expert Review Amber;Literature	Susceptibility to Viral Infections		Immunological disorders	BIALLELIC, autosomal or pseudoautosomal	Immunodeficiency-80 with or without congenital cardiomyopathy (IMD80), MIM#619313;Susceptibility to CMV			Recurrent viral infections;HP:0004429; Severe viral infection;HP:0031691	32865517;33712616		False	2	0;50;50	0.131	True		ENSG00000065328	ENSG00000065328	HGNC:18043													
NFATC2	gene	NFATC2	Expert Review Amber;Literature	Susceptibility to Viral Infections		Immunological disorders	BIALLELIC, autosomal or pseudoautosomal	Lymphoproliferative syndrome, MONDO:0016537, NFATC2-related			Recurrent viral infections;HP:0004429; Severe viral infection;HP:0031691	35789258;38427060		False	2	0;33;67	0.131	True		ENSG00000101096	ENSG00000101096	HGNC:7776													
POLR3A	gene	POLR3A	Expert list;Expert Review Amber	Susceptibility to Viral Infections		Immunological disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Severe VZV infection			Recurrent viral infections;HP:0004429; Severe viral infection;HP:0031691	28783042;29728610		False	2	0;100;0	0.131	True		ENSG00000148606	ENSG00000148606	HGNC:30074													
POLR3C	gene	POLR3C	Expert list;Expert Review Amber	Susceptibility to Viral Infections		Immunological disorders	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Severe VZV infection			Recurrent viral infections;HP:0004429; Severe viral infection;HP:0031691	28783042		False	2	0;100;0	0.131	True		ENSG00000186141	ENSG00000186141	HGNC:30076													
RIPK3	gene	RIPK3	Expert Review Amber;Literature	Susceptibility to Viral Infections		Immunological disorders	BIALLELIC, autosomal or pseudoautosomal	Hereditary susceptibility to infections, MONDO:0015979, RIPK3-related;Recurrent HSV encephalitis			Recurrent viral infections;HP:0004429; Severe viral infection;HP:0031691	PMID: 37083451		False	2	0;100;0	0.131	True		ENSG00000129465	ENSG00000129465	HGNC:10021													
RNASEL	gene	RNASEL	Expert Review Amber;Literature	Susceptibility to Viral Infections		Immunological disorders	BIALLELIC, autosomal or pseudoautosomal	Multisystem inflammatory syndrome, MONDO:0035375, RNASEL-related			Recurrent viral infections;HP:0004429; Severe viral infection;HP:0031691	PMID: 36538032		False	2	0;100;0	0.131	True		ENSG00000135828	ENSG00000135828	HGNC:10050													
UNC93B1	gene	UNC93B1	Expert Review Amber;Melbourne Genomics Health Alliance Immunology Flagship;Victorian Clinical Genetics Services	Susceptibility to Viral Infections		Immunological disorders	BIALLELIC, autosomal or pseudoautosomal	Encephalopathy, acute, infection-induced (herpes-specific), susceptibility to, 1			Recurrent viral infections;HP:0004429; Severe viral infection;HP:0031691	16973841;29768176		False	2	0;100;0	0.131	True		ENSG00000110057	ENSG00000110057	HGNC:13481